公开(公告)号：US11634384B2

公开(公告)日：2023-04-25

申请号：US16427182

申请日：2019-05-30

申请人： Concentric Analgesics, Inc.

发明人： Craig Husfeld ,  John F. Donovan

IPC分类号： C07D211/26 ,  C07C271/52 ,  C07D207/09 ,  C07D295/185

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US10821105B2

公开(公告)日：2020-11-03

申请号：US16303082

申请日：2017-05-24

申请人： CONCENTRIC ANALGESICS, INC.

发明人： John F. Donovan ,  Craig Husfeld

IPC分类号： A61K31/445 ,  A61K45/06 ,  A61K31/165 ,  A61K31/137 ,  A61P29/00

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US09359316B1

公开(公告)日：2016-06-07

申请号：US14743375

申请日：2015-06-18

申请人： Concentric Analgesics, Inc.

发明人： Craig Husfeld ,  John F. Donovan

IPC分类号： C07C271/52 ,  C07D295/195 ,  C07D211/26 ,  C07D207/09

CPC分类号： C07D295/195 ,  C07C271/52 ,  C07D207/09 ,  C07D211/26 ,  C07D295/185

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

摘要翻译： 本文描述了包括这些化合物的化合物，药物组合物和药物，以及使用这些化合物调节瞬时受体潜在的香草素1受体（TRPV1）活性的方法。

公开(公告)号：US11464767B2

公开(公告)日：2022-10-11

申请号：US17031729

申请日：2020-09-24

申请人： Concentric Analgesics, Inc.

发明人： John F. Donovan ,  Craig Husfeld

IPC分类号： A61K31/445 ,  A61K45/06 ,  A61K31/165 ,  A61K31/137 ,  A61P29/00

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US10851123B2

公开(公告)日：2020-12-01

申请号：US16078585

申请日：2017-02-22

申请人： CONCENTRIC ANALGESICS, INC.

发明人： Craig Husfeld ,  Andrei W. Konradi

IPC分类号： A61P29/00 ,  C07F9/09 ,  C07D233/64 ,  C07D207/16 ,  C07C259/06 ,  C07C271/48 ,  C07C271/54 ,  C07C275/42 ,  C07C279/14 ,  C07C305/10 ,  C07C307/02 ,  C07C307/10 ,  C07C323/12 ,  C07C323/44 ,  C07C323/60 ,  C07C233/20 ,  C07C233/27 ,  C07C233/51 ,  C07F9/12 ,  C07F9/24 ,  C07F9/59 ,  C07D211/26 ,  C07D213/81 ,  C07D211/28 ,  C07D295/185 ,  C07D207/09

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US10717712B2

公开(公告)日：2020-07-21

申请号：US16522564

申请日：2019-07-25

申请人： CONCENTRIC ANALGESICS, INC.

发明人： John F. Donovan ,  Craig Husfeld

IPC分类号： C07D241/04

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US11242325B2

公开(公告)日：2022-02-08

申请号：US16895735

申请日：2020-06-08

申请人： CONCENTRIC ANALGESICS, INC.

发明人： John F. Donovan ,  Craig Husfeld

IPC分类号： C07D241/04

摘要： Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.