Tricuspid regurgitation model and methods of evaluating intraluminal medical devices

    公开(公告)号:US10022218B2

    公开(公告)日:2018-07-17

    申请号:US14622165

    申请日:2015-02-13

    Abstract: Animal models useful in the evaluation of medical devices, such as intraluminal medical devices, including intraluminal valve prostheses, are described. An example animal model comprises an animal in which a chordae tendineae attached to at least one of the leaflets of the tricuspid valve has been cut during an interventional procedure. Methods of evaluating intraluminal medical devices are also described. An example methods comprises cutting chordae tendineae attached to a leaflet of a tricuspid valve of an animal; allowing the animal to recover from the step of cutting the chordae tendineae; implanting an intraluminal medical device at a target site within a body vessel of the animal; allowing the animal to recover from the step of implanting an intraluminal medical device; and monitoring in vivo performance of the intraluminal medical device.

    Expandable support frame and medical device

    公开(公告)号:US11406495B2

    公开(公告)日:2022-08-09

    申请号:US15804049

    申请日:2017-11-06

    Abstract: Support frames and medical devices are described. An example medical device comprises an expandable support frame with first and second leaflets attached to the support frame. Each of the first and second leaflets defines a domed radius that is equal to or less than the radius of the expandable support frame when the expandable support frame is in an expanded configuration and the leaflets are subjected to fluid pressure sufficient to affect closure of the valve orifice.

    Tricuspid Regurgitation Model and Methods of Evaluating Intraluminal Medical Devices
    9.
    发明申请
    Tricuspid Regurgitation Model and Methods of Evaluating Intraluminal Medical Devices 有权
    三尖瓣回流模型和评估管腔内医疗器械的方法

    公开(公告)号:US20150230947A1

    公开(公告)日:2015-08-20

    申请号:US14622165

    申请日:2015-02-13

    CPC classification number: A61F2/24 A61F2/2475

    Abstract: Animal models useful in the evaluation of medical devices, such as intraluminal medical devices, including intraluminal valve prostheses, are described. An example animal model comprises an animal in which a chordae tendineae attached to at least one of the leaflets of the tricuspid valve has been cut during an interventional procedure. Methods of evaluating intraluminal medical devices are also described. An example methods comprises cutting chordae tendineae attached to a leaflet of a tricuspid valve of an animal; allowing the animal to recover from the step of cutting the chordae tendineae; implanting an intraluminal medical device at a target site within a body vessel of the animal; allowing the animal to recover from the step of implanting an intraluminal medical device; and monitoring in vivo performance of the intraluminal medical device.

    Abstract translation: 描述了可用于评价医疗装置的动物模型,例如管腔内医疗装置,包括腔内瓣膜假体。 示例性动物模型包括动物,其中在介入手术期间已经切割附着到三尖瓣的至少一个小叶的腱索腱。 还描述了评估管腔内医疗器械的方法。 一个示例性方法包括切割附着在动物三尖瓣瓣叶上的腱索; 允许动物从切割腱索的步骤恢复; 在动物的体内容器内的靶位置植入管腔内医疗装置; 允许动物从植入管腔内医疗装置的步骤中恢复; 并监测管腔内医疗器械的体内性能。

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