公开(公告)号：US20170135337A1

公开(公告)日：2017-05-18

申请号：US15419678

申请日：2017-01-30

Applicant: CORNING INCORPORATED

Inventor： Jessica Monique Brown ,  Nicholas Michael Illsley ,  Gregory Roger Martin ,  Ana Marie del Pilar Pardo ,  Allison Jean Tanner

IPC: A01N1/02

CPC classification number: A01N1/0284 ,  A01N1/0242 ,  A01N1/0263 ,  A01N1/0268 ,  A01N1/0273 ,  A61J1/05 ,  A61J1/1412 ,  A61J1/16 ,  A61M5/145 ,  A61M5/2425 ,  C12M23/48 ,  C12M33/04 ,  C12M45/22

Abstract: An article including, either: a frame having an interior cavity, and a flexible liner situated within the interior cavity; or a deformable frame having an interior cavity, as defined herein. Either frame can receive a sample, such as liquid having suspended live cells, and cooling freezes the sample to a solid sample. The solid sample can be readily ejected from the article having either a frame with the flexible liner, or the deformable frame, without extensive thawing. The solid sample can be rapidly displaced from the article by the methods and apparatus disclosed herein.

公开(公告)号：US20150048085A1

公开(公告)日：2015-02-19

申请号：US14081326

申请日：2013-11-15

Applicant: CORNING INCORPORATED

Inventor： Jessica Monique Brown ,  Nicholas Michael Illsley ,  Gregory Roger Martin ,  Ana Maria del Pilar Pardo ,  Allison Jean Tanner

IPC: A01N1/02

CPC classification number: A01N1/0284 ,  A01N1/0242 ,  A01N1/0263 ,  A01N1/0268 ,  A01N1/0273 ,  A61J1/05 ,  A61J1/1412 ,  A61J1/16 ,  A61M5/145 ,  A61M5/2425 ,  C12M23/48 ,  C12M33/04 ,  C12M45/22

Abstract: An article including, either: a frame having an interior cavity, and a flexible liner situated within the interior cavity; or a deformable frame having an interior cavity, as defined herein. Either frame can receive a sample, such as liquid having suspended live cells, and cooling freezes the sample to a solid sample. The solid sample can be readily ejected from the article having either a frame with the flexible liner, or the deformable frame, without extensive thawing. The solid sample can be rapidly displaced from the article by the methods and apparatus disclosed herein.

Abstract translation: 一种制品，包括：具有内部空腔的框架和位于所述内部空腔内的柔性衬里; 或具有如本文所定义的内腔的可变形框架。 任一框架可以接收样品，例如具有悬浮活细胞的液体，并且冷却将样品冻结成固体样品。 固体样品可以容易地从具有柔性衬垫的框架或可变形框架的制品中排出，而无需大量解冻。 通过本文公开的方法和装置，固体样品可以快速地从制品中移位。

公开(公告)号：US11008157B2

公开(公告)日：2021-05-18

申请号：US15419678

申请日：2017-01-30

Applicant: CORNING INCORPORATED

Inventor： Jessica Monique Brown ,  Nicholas Michael Illsley ,  Gregory Roger Martin ,  Ana Marie del Pilar Pardo ,  Allison Jean Tanner

IPC: B65D83/00 ,  A01N1/02 ,  A61J1/14 ,  A61J1/05 ,  A61J1/16 ,  B65D81/32 ,  B65D21/02 ,  C12M1/26 ,  C12M1/00 ,  C12M3/00 ,  A61M5/145 ,  A61M5/24

Abstract: An article including either a frame having an interior cavity, and a flexible liner situated within the interior cavity; or a deformable frame having an interior cavity. Either frame can receive a sample, such as liquid having suspended live cells, and cooling freezes the sample to a solid sample. The solid sample can be readily ejected from the article having either a frame with the flexible liner, or the deformable frame, without extensive thawing. The solid sample can be rapidly displaced from the article.