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公开(公告)号：US12116188B2
公开(公告)日：2024-10-15
申请号：US17346647
申请日：2021-06-14
CPC分类号： B65D51/002 , A61J1/1406 , A61J1/1412
摘要： A sealing cap for a container for holding a medical liquid comprises a cap body and a connection device having a sealing element arranged on the cap body. The sealing element is arranged at the opening and is retained in the cap body in a clamped manner by a, preferably annular, flanged rim. The connection device has a break-off piece, which is firmly connected to the cap body and covers an outer face of the sealing element in the outward direction. The break-off piece is integral with the cap body, is connected to the cap body by a predetermined breaking point where the break-off piece can be detached from the cap body. The sealing element outer face is substantially flat and is accessible for wiping to provide a sealing cap having a sealing element arranged that can be simply and reliably disinfected.
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公开(公告)号：US20240252399A1
公开(公告)日：2024-08-01
申请号：US18629644
申请日：2024-04-08
申请人： ICU Medical, Inc.
发明人： John M. Seifert , Thomas F. Fangrow
CPC分类号： A61J1/2048 , A61J1/1406 , A61J1/1412 , A61J1/201 , A61J1/2065 , A61J1/2072 , A61J1/2075 , A61J1/2079 , A61J1/2082 , A61J1/2089 , A61J1/2096 , A61J1/2055 , A61J1/2086 , A61J1/22 , A61J2200/10 , A61J2200/76 , Y10T29/49826 , Y10T29/49885 , Y10T137/0402
摘要： In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.
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3.发明授权公开(公告)号：US12023340B2
公开(公告)日：2024-07-02
申请号：US17184463
申请日：2021-02-24
发明人： Carl David Tierney , Andrew John Gardner , Jan Paul Pick-Katolik , Stacey Elaine Powell , Mark Foley , Laurence Charles Ramsey , Andrew George Hardeman
CPC分类号： A61K31/554 , A61J1/1412 , A61J1/1468 , A61K9/0095 , A61K9/107 , A61K45/06 , A61K47/24 , B65B3/003 , B65B7/28
摘要： A quetiapine fumarate composition for oral administration is provided comprising a pharmaceutically acceptable salt or solvate of quetiapine existing as a suspension in an aqueous carrier agent. The inventive liquid formulation demonstrates high bioavailability consistent with approved dosage forms, low agglomeration, reduced content of excipients commonly used in solid oral dosage forms and extended shelf life stability. Also provided is a method of manufacturing a liquid quetiapine suspension composition for oral administration and methods of administering therapeutically effective dosages of an oral liquid quetiapine suspension composition to patients in need thereof.
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4.发明授权公开(公告)号：US12006126B2
公开(公告)日：2024-06-11
申请号：US17011518
申请日：2020-09-03
申请人： BioTillion, LLC
发明人： Hananel Davidowitz , Theodore N. Altman , Ke Wang , Zhengyan Zhai , Jeremy Basch , Ron Or
CPC分类号： B65D81/3825 , A61J1/1412 , A61J2200/44 , A61J2200/50 , A61J2200/72 , A61J2205/60
摘要： A technique for tracking, for example, the temperature of one or more sample vials containing biological material stored in a low-temperature shipping vessel. Each sample vial has vial electronics that senses temperature and transmits temperature data to the reader head of a reader device, which has a controller that is not at the low temperature. In some implementations, the shipping vessel has a cap with a recess that houses the controller and a hollow plug that houses a cable that connects the controller to the reader head that is located in the vessel's cold interior sufficiently close to the sample vial to enable interaction with the vial electronics. In some implementations, the reader head transmits electrical power to the vial electronics. By tracking the temperature of individual sample vials rather than the temperature of the vessel interior, more-relevant temperature data is available.
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公开(公告)号：US11992461B2
公开(公告)日：2024-05-28
申请号：US17333173
申请日：2021-05-28
发明人： Marcus Rainer Rahmel , Guido Endert , Jonas Ruf , Horst Wergen
CPC分类号： A61J1/2051 , A61J1/1412 , A61J1/2027 , A61J1/2048 , A61J1/2089 , B65D21/0231 , B65D43/02 , B65D81/3211 , A61J1/16
摘要： A connecting system for providing a fluidic connection between containers, the connecting system having at least two connecting arrangements configured to produce the fluidic connection. Each container has an initial state in which the two containers are fluidically separated from one another and a connected state in which the two containers have been fluidically connected together by a relative movement of the containers. A securing device prevents relative movement of the containers in the initial state, and a receptacle is provided in which the securing device can be accommodated for enabling said relative movement. The system is usable in a method for preparing a mixture of substances in which the containers are placed in a connecting orientation with the securing device arranged between the containers in a manner preventing fluidic connection of the containers, and releasing the securing device for enabling fluidic connection the containers by a relative connecting movement.
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公开(公告)号：US11969393B2
公开(公告)日：2024-04-30
申请号：US14306443
申请日：2014-06-17
申请人： Tokitae LLC
发明人： John Boomgard , Fong-Li Chou , Philip A. Eckhoff , Fridrik Larusson , Shieng Liu , Krishnan Natarajan , Nels R. Peterson , Lowell L. Wood, Jr.
CPC分类号： A61J1/16 , A61J1/065 , A61J1/1406 , A61J1/1412 , B65D1/095 , B65D21/0201 , A61J2205/10 , A61J2205/30 , A61J2205/60
摘要： In some embodiments, an affixed group of pharmaceutical vials with frangible connectors includes: a plurality of pharmaceutical vials arranged as a group of pharmaceutical vials, each of the plurality of pharmaceutical vials shaped and positioned to minimize a total volume of the group of pharmaceutical vials, each of the pharmaceutical vials including at least one external side with a surface configured to reversibly mate with a corresponding external side and a surface of an adjacent pharmaceutical vial; and a plurality of frangible connectors, wherein at least one frangible connector is affixed to the surface of at least two of the plurality of pharmaceutical vials within the group of pharmaceutical vials, and at least one frangible connector is affixed to each of the plurality of pharmaceutical vials.
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公开(公告)号：US11964282B2
公开(公告)日：2024-04-23
申请号：US18066666
申请日：2022-12-15
CPC分类号： B01L3/5082 , A61J1/1412 , B01L3/502 , B01L2200/023 , G01N33/80
摘要： A biological false bottom transport tube system includes a top section of a specimen tube body, the top section comprising a top, a semi-spherical interior floor, and a bottom below the interior floor, the top section manufactured from a material transparent to both visible and infrared light, wherein the top section may hold a sample on the interior floor; and a bottom section of the specimen tube body, the bottom section comprises a top of a diameter less than a dimeter defined by a remainder of the bottom section, the top of the bottom section fits into the bottom of the top section below the interior floor such that the top of the bottom section is secured within the bottom of the top section, the bottom section manufactured from a material that is not transparent to either visible or infrared light.
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公开(公告)号：US11911342B2
公开(公告)日：2024-02-27
申请号：US17058201
申请日：2019-05-24
发明人： Bo Yan , Longxiang Huang
CPC分类号： A61J1/2096 , A61J1/1412 , A61J1/201 , A61J1/2027
摘要： A connector for connecting a medical injection device, including a barrel and a needle extending from a distal tip of the barrel, to a container including a septum includes an inner deformable cover and an outer rigid cover. The inner deformable cover extends along a cover axis and includes a proximal connection part configured to engage the distal tip of the barrel and a distal portion. The outer rigid cover encloses the inner deformable cover and includes a distal adaptor configured to engage the container. The outer cover is configured so the needle tip extends into the distal adaptor when the proximal connection part of the inner deformable cover engages the distal tip of the barrel. The outer rigid cover is fixed to the inner deformable cover. The inner deformable cover is compressible between a relaxed configuration and a compressed configuration.
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公开(公告)号：US11911340B2
公开(公告)日：2024-02-27
申请号：US17255883
申请日：2019-06-28
发明人： Conny Jakobsson
CPC分类号： A61J1/1412 , A61J1/12 , B65D17/4011 , B65D23/06 , B65D47/066
摘要： A fluid container for holding a fluid, specifically adapted for improved user handling by reducing the risk of fluid spillage in combination with easy extraction of the fluid comprised in the container. The present disclosure also relates to a fluid container system.
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公开(公告)号：US11903902B2
公开(公告)日：2024-02-20
申请号：US18092235
申请日：2022-12-31
CPC分类号： A61J1/2089 , A61J1/1412 , A61J1/2058 , A61J1/2065 , A61J1/2096 , A61M39/10 , A61J1/1418 , A61M2039/1077
摘要： Fluid transfer couplings or connectors including dual function press-in bottle adaptors supporting different syringe types, connectors having a universal port for supporting different syringe types, transfer couplings compatible for use with different syringe types. Other caps and closures incorporating couplings for fluid transfer with different syringe types is also disclosed.
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