公开(公告)号：US11998616B2

公开(公告)日：2024-06-04

申请号：US17215443

申请日：2021-03-29

Applicant: California Institute of Technology

Inventor： Mark E. Davis ,  Emily A. Wyent

IPC: A61K47/69 ,  A61K9/16 ,  A61K31/137 ,  A61K31/4045 ,  A61K31/4745 ,  B82Y5/00 ,  C07K16/32

CPC classification number: A61K47/6935 ,  A61K9/1641 ,  A61K31/137 ,  A61K31/4045 ,  A61K31/4745 ,  C07K16/32 ,  B82Y5/00 ,  Y10S977/773 ,  Y10S977/906

Abstract: The present application discloses nanoparticles carrying therapeutic agents, including chemotherapeutic agents, and targeting ligands suitable for delivering these therapeutic agents through the blood brain barrier and methods of using these patients on those patients in need of such treatment.