公开(公告)号：US20200157102A1

公开(公告)日：2020-05-21

申请号：US16692518

申请日：2019-11-22

Applicant: California Institute of Technology

Inventor： Brian M. Stoltz ,  Eric R. Welin ,  Scott C. Virgil ,  Pamela Tadross ,  Gerit M. Pototschnig ,  Aurapat (Fa) Ngamnithiporn ,  Kenji Negoro ,  Guillaume Lapointe ,  Max Klatte ,  Christopher Haley ,  Christian Gruenanger ,  Emil Glibstrup ,  Christopher Gilmore ,  Kevin McCormack Allan

IPC: C07D471/18 ,  C07D401/04 ,  A61P35/00

Abstract: (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.

公开(公告)号：US10526334B2

公开(公告)日：2020-01-07

申请号：US16038968

申请日：2018-07-18

Applicant: California Institute of Technology

Inventor： Brian M. Stoltz ,  Eric R. Welin ,  Scott C. Virgil ,  Pamela Tadross ,  Gerit Maria Pototschnig ,  Aurapat (Fa) Ngamnithiporn ,  Kenji Negoro ,  Guillaume Lapointe ,  Max Klatte ,  Christopher Haley ,  Christian Gruenanger ,  Emil Glibstrup ,  Christopher Gilmore ,  Kevin McCormack Allan

IPC: C07D471/18 ,  A61P35/00 ,  C07D401/04

Abstract: (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.

公开(公告)号：US10781213B2

公开(公告)日：2020-09-22

申请号：US16692518

申请日：2019-11-22

Applicant: California Institute of Technology

Inventor： Brian M. Stoltz ,  Eric R. Welin ,  Scott C. Virgil ,  Pamela Tadross ,  Gerit M. Pototschnig ,  Aurapat (Fa) Ngamnithiporn ,  Kenji Negoro ,  Guillaume Lapointe ,  Max Klatte ,  Christopher Haley ,  Christian Gruenanger ,  Emil Glibstrup ,  Christopher Gilmore ,  Kevin McCormack Allan

IPC: C07D471/18 ,  A61P35/00 ,  C07D401/04

Abstract: (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.

公开(公告)号：US20190048009A1

公开(公告)日：2019-02-14

申请号：US16038968

申请日：2018-07-18

Applicant: California Institute of Technology

Inventor： Brian M. Stoltz ,  Eric R. Welin ,  Scott C. Virgil ,  Pamela Tadross ,  Gerit Maria Pototschnig ,  Aurapat (Fa) Ngamnithiporn ,  Kenji Negoro ,  Guillaume Lapointe ,  Max Klatte ,  Christopher Haley ,  Christian Gruenanger ,  Emil Glibstrup ,  Christopher Gilmore ,  Kevin McCormack Allan

IPC: C07D471/18 ,  C07D401/04 ,  A61P35/00

CPC classification number: C07D471/18 ,  A61P35/00 ,  C07D401/04

Abstract: (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.