公开(公告)号：US20180087059A1

公开(公告)日：2018-03-29

申请号：US15833890

申请日：2017-12-06

Applicant: CALYSTA, INC.

Inventor： Joshua A. SILVERMAN ,  Effendi LEONARD ,  Renee M. SAVILLE

IPC: C12N15/52 ,  C12N1/20 ,  C12N9/12 ,  C12N9/04 ,  C12N9/00

CPC classification number: C12N15/52 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/1205 ,  C12N9/93 ,  C12Y101/01008 ,  C12Y101/01027 ,  C12Y207/0103 ,  C12Y602/01001

Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glycerol) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.

公开(公告)号：US20170211102A1

公开(公告)日：2017-07-27

申请号：US15311080

申请日：2015-05-14

Applicant: CALYSTA, INC.

Inventor： Lorraine Joan GIVER ,  Joshua A. SILVERMAN ,  John H GRATE

IPC: C12P11/00 ,  C12N1/20 ,  C12N15/52

CPC classification number: C12P11/00 ,  C12N1/20 ,  C12N15/52 ,  C12P7/64 ,  Y02E50/343

Abstract: The present disclosure provides compositions and methods for biologically producing very long carbon chain compounds (longer than C24), such as fatty acyl-CoA, fatty aldehydes, fatty alcohols, fatty ester waxes, alkanes and ketones, from recombinant C1 metabolizing microorganisms that utilize C1 substrates, such as methane or natural gas as a feedstock.

公开(公告)号：US20240228942A1

公开(公告)日：2024-07-11

申请号：US18430443

申请日：2024-02-01

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Joshua A. SILVERMAN ,  Graham Ian AYLEN

IPC: C12M1/00 ,  B01D19/00 ,  C12M1/107 ,  C12M1/12

CPC classification number: C12M45/04 ,  B01D19/00 ,  B01D19/0042 ,  C12M21/04 ,  C12M21/12 ,  C12M23/06 ,  C12M29/18 ,  C12M29/20

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US20210261906A1

公开(公告)日：2021-08-26

申请号：US17199981

申请日：2021-03-12

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Joshua A. SILVERMAN ,  Graham Ian AYLEN

IPC: C12M1/00 ,  C12M1/107 ,  C12M1/12 ,  B01D19/00

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US20200263123A1

公开(公告)日：2020-08-20

申请号：US16862026

申请日：2020-04-29

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Joshua A. SILVERMAN ,  Graham Ian AYLEN

IPC: C12M1/00 ,  C12M1/107 ,  C12M1/12 ,  B01D19/00

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US20180112224A1

公开(公告)日：2018-04-26

申请号：US15821510

申请日：2017-11-22

Applicant: CALYSTA, INC.

Inventor： Joshua A. SILVERMAN ,  Effendi LEONARD ,  Renee M. SAVILLE

IPC: C12N15/52 ,  C12N1/20 ,  C12N9/00 ,  C12N9/12 ,  C12N9/04

CPC classification number: C12N15/52 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/1205 ,  C12N9/93 ,  C12Y101/01008 ,  C12Y101/01027 ,  C12Y207/0103 ,  C12Y602/01001

Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glucose) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.