公开(公告)号：US20150047064A1

公开(公告)日：2015-02-12

申请号：US14522335

申请日：2014-10-23

Applicant: Cancer Research Technology Limited

Inventor： Magdalena Zernicka-Goetz ,  Florence Wianny ,  Martin John Evans ,  David Moore Glover

IPC: C12N15/113 ,  A01K67/027

CPC classification number: C12N15/113 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2217/058 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/03 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N15/1138 ,  C12N15/63 ,  C12N15/8509 ,  C12N2015/8527 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30 ,  C12N2330/50 ,  C12Y207/11001 ,  C12Y302/01031

Abstract: The present invention relates to the specific inhibition of gene expression in mammals by bringing the target gene into contact with double stranded RNA (dsRNA).

Abstract translation: 本发明涉及通过使靶基因与双链RNA（dsRNA）接触来对哺乳动物中基因表达的特异性抑制。

公开(公告)号：US20180355352A1

公开(公告)日：2018-12-13

申请号：US15660556

申请日：2017-07-26

Applicant: Cancer Research Technology Limited

Inventor： Magdalena Zernicka-Goetz ,  Florence Wianny ,  Martin John Evans ,  David Moore Glover

IPC: C12N15/113 ,  C12N15/63 ,  C12N15/85 ,  C12N15/11 ,  A01K67/027 ,  A61K38/00

CPC classification number: C12N15/113 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2217/058 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/03 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N15/1138 ,  C12N15/63 ,  C12N15/8509 ,  C12N2015/8527 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30 ,  C12N2330/50 ,  C12Y207/11001 ,  C12Y302/01031

Abstract: The present invention relates to the specific inhibition of gene expression in mammals by bringing the target gene into contact with double stranded RNA (dsRNA).

公开(公告)号：US20170096667A1

公开(公告)日：2017-04-06

申请号：US15294181

申请日：2016-10-14

Applicant: Cancer Research Technology Limited

Inventor： Magdalena Zernicka-Goetz ,  Florence Wianny ,  Martin John Evans ,  David Moore Glover

IPC: C12N15/113 ,  A01K67/027 ,  C12N15/85

CPC classification number: C12N15/113 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2217/058 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/03 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N15/1138 ,  C12N15/63 ,  C12N15/8509 ,  C12N2015/8527 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30 ,  C12N2330/50 ,  C12Y207/11001 ,  C12Y302/01031

Abstract: The present invention relates to the specific inhibition of gene expression in mammals by bringing the target gene into contact with double stranded RNA (dsRNA).