IMPLANTABLE LEADS WITH TOPOGRAPHIC FEATURES FOR CELLULAR MODULATION AND RELATED METHODS

    公开(公告)号:US20170326358A1

    公开(公告)日:2017-11-16

    申请号:US15667254

    申请日:2017-08-02

    Abstract: An implantable lead including a lead body, an electrode coupled to the lead body, and at least one cellular modulation segment. The lead body has a proximal end and a distal end. The lead body includes an outer layer defining a lumen. The outer layer has an outside surface. The electrical conductor is disposed within the lumen of the outer layer. The electrode is coupled to the lead body. The electrode is in electrical communication with the electrical conductor. The at least one cellular modulation segment is on the outside surface of the outer layer. The at least one cellular modulation segment includes topographic surface features configured to modulate cellular responses. The topographic surface features include a plurality of raised nodes and a plurality of raised ridges interconnecting the plurality of nodes and forming a lattice structure.

    IMPLANTABLE DEVICES AND METHODS FOR CONTROL OF BACTERIAL INFECTIONS

    公开(公告)号:US20210121683A1

    公开(公告)日:2021-04-29

    申请号:US17076313

    申请日:2020-10-21

    Abstract: An implantable antibacterial barrier device for an elongated medical device, the elongated medical device configured to extend from a first site, through a second site, to a third site. The implantable antibacterial barrier device includes a housing configured to be disposed at the first site, a working electrode configured to be disposed at the second site, and a reference electrode configured to be disposed at the first site. The housing includes barrier circuitry. The working electrode electrically is coupled to the barrier circuitry. The reference electrode is electrically coupled to the barrier circuitry. The barrier circuitry is configured to selectively maintain the working electrode at a negative electrical potential relative to the reference electrode to form an antibacterial barrier.

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