IMPLANTABLE LEADS WITH TOPOGRAPHIC FEATURES FOR CELLULAR MODULATION AND RELATED METHODS

    公开(公告)号:US20170326358A1

    公开(公告)日:2017-11-16

    申请号:US15667254

    申请日:2017-08-02

    Abstract: An implantable lead including a lead body, an electrode coupled to the lead body, and at least one cellular modulation segment. The lead body has a proximal end and a distal end. The lead body includes an outer layer defining a lumen. The outer layer has an outside surface. The electrical conductor is disposed within the lumen of the outer layer. The electrode is coupled to the lead body. The electrode is in electrical communication with the electrical conductor. The at least one cellular modulation segment is on the outside surface of the outer layer. The at least one cellular modulation segment includes topographic surface features configured to modulate cellular responses. The topographic surface features include a plurality of raised nodes and a plurality of raised ridges interconnecting the plurality of nodes and forming a lattice structure.

    Fixation and strain relief element for temporary therapy delivery device
    7.
    发明授权
    Fixation and strain relief element for temporary therapy delivery device 有权
    用于临时治疗输送装置的固定和应变消除元件

    公开(公告)号:US09486622B2

    公开(公告)日:2016-11-08

    申请号:US14030741

    申请日:2013-09-18

    CPC classification number: A61N1/0558

    Abstract: A temporary neurostimulation lead may be secured relative to patient using a fixation device. The fixation device may include an attachment portion that is configured to be releasably fixated to the patient and a lead fixation portion that is configured to secure the temporary neurostimulation lead. The fixation device can be adhesively fixated to the patient via the attachment portion and the temporary neurostimulation lead can be fixated to the lead fixation portion of the fixation device.

    Abstract translation: 可以使用固定装置相对于患者来确保暂时的神经刺激引线。 固定装置可以包括被配置为可释放地固定到患者的附接部分和被配置为固定临时神经刺激引线的引导固定部分。 固定装置可以经由附接部分粘合固定在患者身上,临时神经刺激引线可以固定在固定装置的引导固定部分上。

    System and method for pacing rate control utilizing patient hemodynamic status information
    8.
    发明授权
    System and method for pacing rate control utilizing patient hemodynamic status information 失效
    使用患者血液动力学状态信息进行起搏速率控制的系统和方法

    公开(公告)号:US08583232B2

    公开(公告)日:2013-11-12

    申请号:US13858270

    申请日:2013-04-08

    CPC classification number: A61N1/36564 A61N1/36542 A61N1/36585

    Abstract: A system and method for pacing rate control in a cardiac rhythm management (CRM) system. The method includes acquiring a pressure signal representative of coronary venous pressure (CVP) from a pressure sensor implanted within a coronary vein of the patient and generating a CVP waveform from the pressure signal. A pacing stimulus is applied to the patient's heart, and the pacing rate is increased in response to increases in patient's metabolic demand. The CVP index is monitored during the pacing rate increase, and the CRM system detects a reduction in the patient's hemodymanic performance based on the CVP index and establishes a maximum rate setting based on the pacing rate corresponding to the reduction in the patient's hemodynamic performance.

    Abstract translation: 用于心律管理(CRM)系统中起搏速率控制的系统和方法。 该方法包括从植入患者冠状静脉内的压力传感器获取代表冠状静脉压(CVP)的压力信号,并从压力信号产生CVP波形。 对患者的心脏施加起搏刺激,并且响应于患者代谢需求的增加而起搏速率增加。 在起搏速率增加期间监测CVP指数,并且CRM系统基于CVP指数检测患者血液动力学性能的降低,并且基于与患者血液动力学性能的降低相对应的起搏速率来建立最大速率设定。

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