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    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT
    1.
    发明申请
    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT 有权
    具有抗感染剂的可植入医疗器械

    公开(公告)号：US20090292327A1

    公开(公告)日：2009-11-26

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Low-profile implantable medical device
    2.
    发明授权
    Low-profile implantable medical device 有权
    低调植入式医疗器械

    公开(公告)号：US08457744B2

    公开(公告)日：2013-06-04

    申请号：US10730877

    申请日：2003-12-09

    申请人： Darren A. Janzig ,  Carl D. Wahlstrand ,  Paulette C. Olson ,  Robert M. Skime

    发明人： Darren A. Janzig ,  Carl D. Wahlstrand ,  Paulette C. Olson ,  Robert M. Skime

    IPC分类号： A61N1/08

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

    摘要： Components of an implantable medical device are arranged to facilitate a low-profile housing. A circuit board within the housing carries integrated circuits and discrete components. In some embodiments, the integrated circuits and discrete components are located on first and second opposing surfaces of the circuit board, respectively. In some embodiments, the implantable medical device is implanted on a cranium of a patient and the housing is concave such that it substantially conforms to the cranium. In such embodiments, the integrated circuits and/or discrete components can be arranged on the circuit board according to height to better conform to the concavity of the housing. In some embodiments, the implantable medical device includes a telemetry coil that is positioned within the housing such that it occupies space that cannot be practically occupied by the circuit board.

    摘要翻译： 可植入医疗装置的部件被布置成便于小型外壳。 外壳内的电路板承载集成电路和分立元件。 在一些实施例中，集成电路和分立元件分别位于电路板的第一和第二相对表面上。 在一些实施例中，将可植入医疗装置植入患者的颅骨上，并且所述外壳是凹形的，使得其基本上符合颅骨。 在这样的实施例中，集成电路和/或分立组件可以根据高度布置在电路板上，以更好地符合壳体的凹面。 在一些实施例中，可植入医疗装置包括位于壳体内的遥测线圈，使其占据不能被电路板实际占据的空间。

    Implantable medical device with anti-infection agent
    3.
    发明授权
    Implantable medical device with anti-infection agent 失效
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US07596408B2

    公开(公告)日：2009-09-29

    申请号：US10837319

    申请日：2004-04-30

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device with anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 具有抗感染剂的可植入医疗器械。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Reducing relative intermodule motion in a modular implantable medical device
    4.
    发明授权
    Reducing relative intermodule motion in a modular implantable medical device 失效
    在模块化可植入医疗设备中减少相对模块间运动

    公开(公告)号：US07392089B2

    公开(公告)日：2008-06-24

    申请号：US10731881

    申请日：2003-12-09

    申请人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Robert M. Skime

    发明人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Robert M. Skime

    IPC分类号： A61N1/36

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

    摘要： A modular implantable medical device includes a plurality of modules that are at least partially encapsulated by an overmold. The modules may be connected by coupling modules, which may be flexible to provide for one or more degrees of relative intermodular motion. The overmold may also be flexible. In order to reduce relative intermodule motion to acceptable direction and/or ranges, the overmold may include one or more motion reduction elements.

    摘要翻译： 模块化可植入医疗装置包括至少部分地由包覆成型包封的多个模块。 模块可以通过耦合模块连接，耦合模块可以是柔性的，以提供一个或多个相对的模块间运动程度。 包覆成型也可以是柔性的。 为了将相对模块间运动减小到可接受的方向和/或范围，包覆模具可以包括一个或多个运动减少元件。

    Overmold for a modular implantable medical device
    5.
    发明授权
    Overmold for a modular implantable medical device 有权
    用于模块化可植入医疗设备的包覆模型

    公开(公告)号：US07242982B2

    公开(公告)日：2007-07-10

    申请号：US10730873

    申请日：2003-12-09

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson

    IPC分类号： A61N1/36

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

    摘要： A modular implantable medical device permits implantable medical devices to have a smaller profile in order to better fit into locations within the human body. A modular implantable medical device separates various functional components of the implantable medical device into a set of interconnected modules. This distributed architecture of a modular implantable medical device may permit the device footprint to be distributed over a larger area while making the profile smaller, and may permit the overall shape of the implantable medical device to better match the body location into which it is to be implanted. An overmold integrates the modules of a modular implantable medical device into a single structure. In some embodiments the overmold is flexible and provides a biocompatible interface from the component modules and the patient, while restraining potentially harmful intermodule motion.

    摘要翻译： 模块化可植入医疗装置允许植入式医疗装置具有更小的外形，以便更好地适应人体内的位置。 模块化可植入医疗装置将可植入医疗装置的各种功能部件分离成一组互连的模块。 模块化可植入医疗设备的这种分布式架构可以允许设备占地面积分布在更大的区域上，同时使轮廓更小，并且可以允许可植入医疗设备的整体形状更好地匹配要被植入的医疗设备的身体位置 植入。 包覆模具将模块化可植入医疗设备的模块集成到单个结构中。 在一些实施方案中，包覆成型是柔性的并且提供来自组件模块和患者的生物相容性界面，同时限制潜在有害的模块间运动。

    Implantable medical device with lubricious material
    7.
    发明授权
    Implantable medical device with lubricious material 有权
    具有光滑材料的植入式医疗器械

    公开(公告)号：US09162072B2

    公开(公告)日：2015-10-20

    申请号：US11526514

    申请日：2006-09-25

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/375 ,  A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/375 ,  A61B2560/0443 ,  A61N1/0526 ,  A61N1/3605

    摘要： An implantable medical device with lubricious material permits implantable medical devices to have a reduced friction between the device and at least a portion of the surrounding tissue. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the tissue. The lubricious material may be provided on or impregnated in the housing or the member. In some embodiments, the device is configured for implantation in the head of a human body. In other embodiments, the device is configured for implantation between the cranium and the scalp. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled together to provide a smaller profile.

    摘要翻译： 具有润滑材料的可植入医疗装置允许植入式医疗装置在装置与周围组织的至少一部分之间具有减小的摩擦。 可植入医疗装置可以具有壳体，或者可以具有壳体和用于在装置和组织之间提供平滑界面的构件。 润滑材料可以设置在或浸渍在壳体或构件中。 在一些实施例中，该装置被配置用于植入人体的头部。 在其他实施例中，该装置被配置用于在颅骨和头皮之间植入。 在一些实施例中，设备包括单个模块，而在其他实施例中，多个模块耦合在一起以提供较小的轮廓。

    Implantable medical device with anti-infection agent
    9.
    发明授权
    Implantable medical device with anti-infection agent 有权
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US08086313B2

    公开(公告)日：2011-12-27

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。