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    Implantable medical device with anti-infection agent
    1.
    发明授权
    Implantable medical device with anti-infection agent 失效
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US07596408B2

    公开(公告)日：2009-09-29

    申请号：US10837319

    申请日：2004-04-30

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device with anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 具有抗感染剂的可植入医疗器械。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT
    2.
    发明申请
    IMPLANTABLE MEDICAL DEVICE WITH ANTI-INFECTION AGENT 有权
    具有抗感染剂的可植入医疗器械

    公开(公告)号：US20090292327A1

    公开(公告)日：2009-11-26

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Implantable medical device with lubricious material
    3.
    发明授权
    Implantable medical device with lubricious material 有权
    具有光滑材料的植入式医疗器械

    公开(公告)号：US09162072B2

    公开(公告)日：2015-10-20

    申请号：US11526514

    申请日：2006-09-25

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/375 ,  A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/375 ,  A61B2560/0443 ,  A61N1/0526 ,  A61N1/3605

    摘要： An implantable medical device with lubricious material permits implantable medical devices to have a reduced friction between the device and at least a portion of the surrounding tissue. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the tissue. The lubricious material may be provided on or impregnated in the housing or the member. In some embodiments, the device is configured for implantation in the head of a human body. In other embodiments, the device is configured for implantation between the cranium and the scalp. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled together to provide a smaller profile.

    摘要翻译： 具有润滑材料的可植入医疗装置允许植入式医疗装置在装置与周围组织的至少一部分之间具有减小的摩擦。 可植入医疗装置可以具有壳体，或者可以具有壳体和用于在装置和组织之间提供平滑界面的构件。 润滑材料可以设置在或浸渍在壳体或构件中。 在一些实施例中，该装置被配置用于植入人体的头部。 在其他实施例中，该装置被配置用于在颅骨和头皮之间植入。 在一些实施例中，设备包括单个模块，而在其他实施例中，多个模块耦合在一起以提供较小的轮廓。

    Implantable medical device with anti-infection agent
    4.
    发明授权
    Implantable medical device with anti-infection agent 有权
    具有抗感染剂的植入式医疗器械

    公开(公告)号：US08086313B2

    公开(公告)日：2011-12-27

    申请号：US12536258

    申请日：2009-08-05

    申请人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    发明人： Ruchika Singhal ,  Darren A. Janzig ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Paulette C. Olson ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/02

    CPC分类号： A61N1/3754 ,  A61B5/076 ,  A61B2560/04 ,  A61L31/16 ,  A61L2300/404 ,  A61N1/3605 ,  A61N1/375

    摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

    摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。

    Concavity of an implantable medical device
    5.
    发明授权
    Concavity of an implantable medical device 有权
    可植入医疗器械的凹陷

    公开(公告)号：US07529586B2

    公开(公告)日：2009-05-05

    申请号：US10731867

    申请日：2003-12-09

    申请人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Ruchika Singhal ,  Robert M. Skime ,  Erik R. Scott ,  James E. Randall

    发明人： Carl D. Wahlstrand ,  Darren A. Janzig ,  Ruchika Singhal ,  Robert M. Skime ,  Erik R. Scott ,  James E. Randall

    IPC分类号： A61N1/36

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

    摘要： At least one surface of an implantable medical device is concave along at least one axis such that it substantially conforms to a surface within a patient, such as the cranium, when it is implanted on that surface. In some embodiments, the surface of the implantable medical device substantially conforms to an arc with a radius that is between 4.5 and 9.5 centimeters, and is preferably approximately equal to 7 centimeters. In some embodiments, the implantable medical device comprises a plurality of interconnected modules, and an overmold that at least partially encapsulates each of the modules. In such embodiments, at least one surface of the overmold is concave along at least one axis. Further, each of the modules of such an implantable medical device may comprise a housing, and at least one surface of at least one of the housings may be concave along at least one axis.

    摘要翻译： 可植入医疗装置的至少一个表面沿着至少一个轴线是凹形的，使得当植入在该表面上时，其基本上符合患者（例如颅骨）内的表面。 在一些实施例中，可植入医疗装置的表面基本上符合半径在4.5和9.5厘米之间的弧度，并且优选地大约等于7厘米。 在一些实施例中，可植入医疗装置包括多个互连的模块，以及至少部分地封装每个模块的包覆模制。 在这样的实施例中，包覆模制体的至少一个表面沿着至少一个轴线是凹形的。 此外，这种可植入医疗装置的每个模块可以包括壳体，并且至少一个壳体的至少一个表面沿着至少一个轴线可以是凹形的。

    Implantable medical device with a nonhermetic battery
    6.
    发明授权
    Implantable medical device with a nonhermetic battery 有权
    具有非密封电池的可植入医疗器械

    公开(公告)号：US07263401B2

    公开(公告)日：2007-08-28

    申请号：US10835233

    申请日：2004-04-29

    申请人： Erik R. Scott ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Craig L. Schmidt

    发明人： Erik R. Scott ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Craig L. Schmidt

    IPC分类号： A61N1/00 ,  H01J5/00

    CPC分类号： A61N1/375 ,  A61N1/378

    摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.

    摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。

    Implantable medical device with a nonhermetic battery
    7.
    发明授权
    Implantable medical device with a nonhermetic battery 有权
    具有非密封电池的可植入医疗器械

    公开(公告)号：US07881796B2

    公开(公告)日：2011-02-01

    申请号：US11831333

    申请日：2007-07-31

    申请人： Erik R. Scott ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Craig L. Schmidt

    发明人： Erik R. Scott ,  Carl D. Wahlstrand ,  Robert M. Skime ,  Craig L. Schmidt

    IPC分类号： A61N1/08

    CPC分类号： A61N1/375 ,  A61N1/378

    摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.

    摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。

    Variable recharge determination for an implantable medical device and method therefore
    8.
    发明授权
    Variable recharge determination for an implantable medical device and method therefore 有权
    因此，可植入式医疗装置的可变补充确定和方法

    公开(公告)号：US07616995B2

    公开(公告)日：2009-11-10

    申请号：US11414156

    申请日：2006-04-28

    申请人： Carl D. Wahlstrand ,  Robert M. Skime ,  Erik R. Scott ,  Craig L. Schmidt

    发明人： Carl D. Wahlstrand ,  Robert M. Skime ,  Erik R. Scott ,  Craig L. Schmidt

    IPC分类号： A61N1/378

    CPC分类号： A61N1/3787

    摘要： Implantable medical device adapted to provide a therapeutic output to a patient. A therapy module, operatively coupled to a battery, is adapted to provide the therapeutic output. A control circuit provides an action indicative of recharging the battery when the voltage of the battery reaches a recharge voltage wherein the recharge voltage is varied as the battery ages. Also a method of providing a therapeutic output to a patient using an implantable medical device having a battery having a voltage. An action indicative of recharging the battery is provided when the voltage of the battery reaches a recharge voltage. The recharge voltage is varied as the battery ages.

    摘要翻译： 适于向患者提供治疗输出的可植入医疗装置。 可操作地耦合到电池的治疗模块适于提供治疗输出。 当电池的电压达到再充电电压时，控制电路提供指示对电池再充电的动作，其中充电电压随电池老化而变化。 还有一种使用具有电压的电池的可植入医疗装置向患者提供治疗输出的方法。 当电池的电压达到充电电压时，提供指示对电池再充电的动作。 充电电压随电池老化而变化。