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公开(公告)号:US20090074715A1
公开(公告)日:2009-03-19
申请号:US12180994
申请日:2008-07-28
IPC分类号: A61K38/20 , C07D223/16 , A61K31/55 , A61P31/14 , A61K38/21
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US20090042860A1
公开(公告)日:2009-02-12
申请号:US12184791
申请日:2008-08-01
申请人: Carl P. Bergstrom , Scott W. Martin
发明人: Carl P. Bergstrom , Scott W. Martin
IPC分类号: A61K31/55 , C07D223/32 , A61P31/00
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07652004B2
公开(公告)日:2010-01-26
申请号:US12180994
申请日:2008-07-28
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US20090275561A1
公开(公告)日:2009-11-05
申请号:US12369222
申请日:2009-02-11
IPC分类号: A61K31/55 , C07D403/04 , C07D413/14 , C07D401/14 , C07D487/04 , A61K31/551
CPC分类号: C07D487/04 , C07D401/14 , C07D403/04 , C07D409/04 , C07D413/04 , C07D413/14
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07521441B2
公开(公告)日:2009-04-21
申请号:US11745090
申请日:2007-05-07
申请人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
发明人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
IPC分类号: A61P31/00 , A61K31/407 , C07D487/00
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07473688B2
公开(公告)日:2009-01-06
申请号:US11516435
申请日:2006-09-06
申请人: Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
发明人: Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
IPC分类号: A61K31/55 , A61P31/00 , C07D223/14
CPC分类号: C07D491/14 , C07D487/04
摘要: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I,II,III和IV的化合物和盐以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US08133884B2
公开(公告)日:2012-03-13
申请号:US12434748
申请日:2009-05-04
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04 , C07D471/08 , C07D487/08 , C07D498/08
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07642251B2
公开(公告)日:2010-01-05
申请号:US12184791
申请日:2008-08-01
申请人: Carl P. Bergstrom , Scott W. Martin
发明人: Carl P. Bergstrom , Scott W. Martin
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07348425B2
公开(公告)日:2008-03-25
申请号:US11347765
申请日:2006-02-03
申请人: Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
发明人: Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
IPC分类号: A61K31/55 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/425 , A61K31/427 , A61K31/403 , C07D233/32 , C07D413/14 , C07D409/14
CPC分类号: C07D471/04 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/13 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K45/06 , C07D471/14 , C07D487/04 , C07D487/14 , C07D491/14 , C07D498/14 , C07D513/14 , A61K2300/00
摘要: Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds
摘要翻译: 描述式I的吲哚化合物。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。 还描述了包含化合物的不同形式和组合物以及制备化合物的方法
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公开(公告)号:US08143243B2
公开(公告)日:2012-03-27
申请号:US12369222
申请日:2009-02-11
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04 , C07D401/14 , C07D403/04 , C07D409/04 , C07D413/04 , C07D413/14
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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