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公开(公告)号：US08133884B2
公开(公告)日：2012-03-13
申请号：US12434748
申请日：2009-05-04
IPC分类号： A61P31/00 , A61K31/55 , C07D223/14
CPC分类号： C07D487/04 , C07D471/08 , C07D487/08 , C07D498/08
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US07521441B2
公开(公告)日：2009-04-21
申请号：US11745090
申请日：2007-05-07
申请人： Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
发明人： Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
IPC分类号： A61P31/00 , A61K31/407 , C07D487/00
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US07348425B2
公开(公告)日：2008-03-25
申请号：US11347765
申请日：2006-02-03
申请人： Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
发明人： Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
IPC分类号： A61K31/55 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/425 , A61K31/427 , A61K31/403 , C07D233/32 , C07D413/14 , C07D409/14
CPC分类号： C07D471/04 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/13 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K45/06 , C07D471/14 , C07D487/04 , C07D487/14 , C07D491/14 , C07D498/14 , C07D513/14 , A61K2300/00
摘要： Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds
摘要翻译： 描述式I的吲哚化合物。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。 还描述了包含化合物的不同形式和组合物以及制备化合物的方法
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公开(公告)号：US20090280083A1
公开(公告)日：2009-11-12
申请号：US12434748
申请日：2009-05-04
IPC分类号： A61K31/55 , C07D405/14 , A61K38/20 , A61K38/21 , A61K38/13 , A61P31/14 , C07D417/14 , C07D405/04
CPC分类号： C07D487/04 , C07D471/08 , C07D487/08 , C07D498/08
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US20070270406A1
公开(公告)日：2007-11-22
申请号：US11745090
申请日：2007-05-07
申请人： Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
发明人： Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
IPC分类号： A61K31/55 , C07D487/04
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US07153848B2
公开(公告)日：2006-12-26
申请号：US11181639
申请日：2005-07-14
申请人： Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
发明人： Thomas W. Hudyma , Xiaofan Zheng , Feng He , Min Ding , Carl P. Bergstrom , Piyasena Hewawasam , Scott W. Martin , Robert G. Gentles
IPC分类号： A61K31/55 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/425 , A61K31/427 , A61K31/4178 , A61K31/4184 , A61K31/4025 , A61K31/403 , C07D233/32 , C07D413/14 , C07D409/14
CPC分类号： C07D471/04 , C07D471/14 , C07D487/04 , C07D487/14 , C07D491/14 , C07D513/14
摘要： Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.
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公开(公告)号：US07473688B2
公开(公告)日：2009-01-06
申请号：US11516435
申请日：2006-09-06
申请人： Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
发明人： Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
IPC分类号： A61K31/55 , A61P31/00 , C07D223/14
CPC分类号： C07D491/14 , C07D487/04
摘要： The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I，II，III和IV的化合物和盐以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US20090074715A1
公开(公告)日：2009-03-19
申请号：US12180994
申请日：2008-07-28
IPC分类号： A61K38/20 , C07D223/16 , A61K31/55 , A61P31/14 , A61K38/21
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US07652004B2
公开(公告)日：2010-01-26
申请号：US12180994
申请日：2008-07-28
IPC分类号： A61P31/00 , A61K31/55 , C07D223/14
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US20090275561A1
公开(公告)日：2009-11-05
申请号：US12369222
申请日：2009-02-11
IPC分类号： A61K31/55 , C07D403/04 , C07D413/14 , C07D401/14 , C07D487/04 , A61K31/551
CPC分类号： C07D487/04 , C07D401/14 , C07D403/04 , C07D409/04 , C07D413/04 , C07D413/14
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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