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公开(公告)号：US4829001A
公开(公告)日：1989-05-09
申请号：US796272
申请日：1985-11-08
申请人： Arlene J. Mencke , Carol E. Hendrickson , Rosa Uy
发明人： Arlene J. Mencke , Carol E. Hendrickson , Rosa Uy
CPC分类号： A61L2/18 , A61L12/126 , C11D3/0078
摘要： A method for disinfecting a medical device comprising the steps of immersing a medical device in a hydrogen peroxide solution for a time sufficient to disinfect said device, decomposing any residual hydrogen peroxide by use of a catalytically effective amount of a protein capable of decomposing hydrogen peroxide, said protein being immobilized on a composite article, said composite article comprising in sequence a support, a layer of protein immobilizer compound, and a biologically active protein. The surface modification treatment is a gelled network of inorganic oxide particles or a plasma treatment.
摘要翻译： 一种消毒医疗装置的方法，包括以下步骤：将医疗装置浸入过氧化氢溶液中足以消毒所述装置的时间，通过使用催化有效量的能够分解过氧化氢的蛋白质分解任何残留的过氧化氢， 所述蛋白质被固定在复合制品上，所述复合制品依次包含支持物，蛋白质固定剂化合物层和生物活性蛋白质。 表面改性处理是无机氧化物颗粒的凝胶网络或等离子体处理。
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2.发明授权Immobilization of biologically active protein on a polymeric fibrous support 失效将生物活性蛋白质固定在聚合物纤维支持体上
公开(公告)号：US4757014A
公开(公告)日：1988-07-12
申请号：US796274
申请日：1985-11-08
申请人： Carol E. Hendrickson , Rosa Uy , Arlene J. Mencke
发明人： Carol E. Hendrickson , Rosa Uy , Arlene J. Mencke
CPC分类号： A61L12/126 , A61L2/18 , C11D3/0078 , Y10S530/811 , Y10S530/815
摘要： A composite article is prepared comprising in sequence a fibrous polymeric support which has been subjected to a surface treatment to provide binding sites thereon, a layer of a protein immobilizer compound, and a biologically active protein. The surface treatment comprises coating the support with a 2 to 500 nm thick layer of inorganic oxide or subjecting the support to a plasma treatment. The protein immobilizer can be a polymer or silane-functional compound. The biologically active protein can be the enzyme, catalase, which has use in decomposing hydrogen peroxide when disinfecting contact lenses.
摘要翻译： 制备复合制品，其中依次包含经过表面处理以提供结合位点的纤维聚合物载体，蛋白质固定化合物层和生物活性蛋白质层。 表面处理包括用2至500nm厚的无机氧化物层涂覆载体或使载体进行等离子体处理。 蛋白质固定剂可以是聚合物或硅烷官能化合物。 生物活性蛋白质可以是酶，过氧化氢酶，其在消毒隐形眼镜时用于分解过氧化氢。
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3.发明授权
公开(公告)号：US4855234A
公开(公告)日：1989-08-08
申请号：US169832
申请日：1988-03-17
申请人： Carol E. Hendrickson , Rosa Uy , Arlene J. Mencke
发明人： Carol E. Hendrickson , Rosa Uy , Arlene J. Mencke
CPC分类号： A61L12/126 , A61L2/18 , C11D3/0078 , Y10S530/811 , Y10S530/815
摘要： A composite article is prepared having in sequence a fibrous support which has been subjected to a surface treatment to provide binding sites thereon, a layer of a protein immobilizer compound, and a biologically active protein such as enzyme. The surface treatment can be carried out by coating the surface with an inorganic oxide or by subjecting the surface to plasma treatment.
摘要翻译： 制备复合制品，其中依次具有经过表面处理以提供结合位点的纤维状载体，蛋白质固定剂化合物层和生物活性蛋白质如酶。 表面处理可以通过用无机氧化物涂覆表面或通过对表面进行等离子体处理来进行。
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公开(公告)号：US4485029A
公开(公告)日：1984-11-27
申请号：US591043
申请日：1984-03-19
申请人： Kenneth H. Kato , Arlene J. Mencke
发明人： Kenneth H. Kato , Arlene J. Mencke
IPC分类号： C11D7/26 , A01N37/12 , A01N37/40 , A61L12/14 , G02C7/04 , G02C13/00 , A61K31/23 , A61K31/235 , A61L13/00 , C11D3/48
CPC分类号： A61L12/14 , A01N37/12 , A01N37/40 , Y10S514/912
摘要： A composition is disclosed which includes the use of glyceryl monolaurate in combination with one or more other anti-microbial agents and, optionally an organic surfactant as a cleaning, disinfecting and preserving system which must be non-irritating and non-allergenic to body tissues. The composition is effective against a variety of microorganisms within a reasonable period of time, at concentrations that, if desired, can result in a visually clear solution. It is useful in a solution for cleaning, disinfecting and preserving contact lenses.
摘要翻译： 公开了一种组合物，其包括将单月桂酸甘油酯与一种或多种其它抗微生物剂组合使用，以及任选的有机表面活性剂作为清洁，消毒和保存系统，其必须对身体组织无刺激性和非致敏性。 该组合物在合理的时间段内对多种微生物有效，如果需要，可以产生视觉上清澈的溶液。 它可用于清洁，消毒和保存隐形眼镜的解决方案。
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公开(公告)号：US4622258A
公开(公告)日：1986-11-11
申请号：US729288
申请日：1985-05-01
申请人： Arlene J. Mencke
发明人： Arlene J. Mencke
CPC分类号： G02C13/008 , Y10S428/903 , Y10T428/24603 , Y10T442/68 , Y10T442/697
摘要： An article and a method for cleaning a contact lens is disclosed, said method comprising providing a moistened non-woven fibrous web wherein the average fiber diameter is up to 50 microns, contacting and rubbing the lens with the fibrous web, and removing the lens from contact with the fibrous web.
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公开(公告)号：US4678698A
公开(公告)日：1987-07-07
申请号：US891865
申请日：1986-07-30
申请人： Arlene J. Mencke
发明人： Arlene J. Mencke
CPC分类号： G02C13/008 , Y10S206/812 , Y10S428/903 , Y10S428/913 , Y10T428/24603 , Y10T442/68
摘要： An article and a method for cleaning a contact lens is disclosed, said method comprising providing a moistened non-woven fibrous web wherein the average fiber diameter is up to 50 microns, contacting and rubbing the lens with the fibrous web, and removing the lens from contact with the fibrous web.
摘要翻译： 公开了一种用于清洁隐形眼镜的制品和方法，所述方法包括提供湿润的无纺纤维织物，其中平均纤维直径高达50微米，用纤维网接触和摩擦透镜，并将透镜从 与纤维网接触。
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公开(公告)号：US4533399A
公开(公告)日：1985-08-06
申请号：US484163
申请日：1983-04-12
申请人： Arlene J. Mencke
发明人： Arlene J. Mencke
CPC分类号： G02C13/008
摘要： An article and a method for cleaning a contact lens is disclosed, said method comprising providing a moistened non-woven fibrous web wherein the average fiber diameter is up to 50 microns, contacting and rubbing the lens with the fibrous web, and removing the lens from contact with the fibrous web.
摘要翻译： 公开了一种用于清洁隐形眼镜的制品和方法，所述方法包括提供湿润的无纺纤维织物，其中平均纤维直径高达50微米，用纤维网接触和摩擦透镜，并将透镜从 与纤维网接触。
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