公开(公告)号：US20210386410A1

公开(公告)日：2021-12-16

申请号：US16902579

申请日：2020-06-16

Applicant: Case Western Reserve University

Inventor： Amitabh Chak ,  Sanford Markowitz ,  Dennis Siedlak ,  Joseph Willis ,  Lishan Aklog ,  Michael Boutillette ,  Richard Yazbeck

IPC: A61B10/02 ,  A61M25/10

Abstract: A device for collecting a biological sample in a subject, the device including an inflatable portion attached to a tubular member, and designed to expand from within the tubular member when inflated and to retract within the tubular member, a surface on the inflatable portion provided with varied thickness to facilitate movement of the inflatable portion between an expanded state and a retracted state, and a plurality of projections on the surface to allow collection of the biological sample when the inflatable portion is in the expanded state.

公开(公告)号：US20210369256A1

公开(公告)日：2021-12-02

申请号：US17331375

申请日：2021-05-26

Applicant: Case Western Reserve University

Inventor： Sanford Markowitz ,  Amitabh Chak ,  Joseph Willis ,  Lishan Aklog ,  Richard Yazbeck ,  Michael Boutillette ,  Brian deGuzman ,  David Wurtman

IPC: A61B10/04

Abstract: A method for collecting a cell sample, including eosinophil white blood cells in a patient is provided. The method includes advancing to a location in an esophagus associated with eosinophilic esophagitis (EoE), a device provided with a collection portion having a first axial end portion and an inflatable second axial end portion. Thereafter, axially moving the second axial end portion, relative to the first axial end portion, from a collapsed position within the first axial end portion into an expanded position out from the first axial end portion. Once the second axial end portion is in the expanded position, allowing it to engage the location associated with EoE to collect a sample of cells.

公开(公告)号：US12262879B2

公开(公告)日：2025-04-01

申请号：US16902579

申请日：2020-06-16

Applicant: Case Western Reserve University

Inventor： Amitabh Chak ,  Sanford Markowitz ,  Dennis Siedlak ,  Joseph Willis ,  Lishan Aklog ,  Michael Boutillette ,  Richard Yazbeck

IPC: A61B10/02 ,  A61B10/04 ,  A61M25/10

Abstract: A device for collecting a biological sample in a subject, the device including an inflatable portion attached to a tubular member, and designed to expand from within the tubular member when inflated and to retract within the tubular member, a surface on the inflatable portion provided with varied thickness to facilitate movement of the inflatable portion between an expanded state and a retracted state, and a plurality of projections on the surface to allow collection of the biological sample when the inflatable portion is in the expanded state.

公开(公告)号：US20230000475A1

公开(公告)日：2023-01-05

申请号：US17855530

申请日：2022-06-30

Applicant: Case Western Reserve University

Inventor： Sanford Markowitz ,  Amitabh Chak ,  Joseph Willis ,  Lishan Aklog ,  Richard Yazbeck ,  Michael Boutillette ,  Brian deGuzman ,  David Wurtman

IPC: A61B10/04

Abstract: Provided herein are methods and a device for collecting biological samples. In particular, the present disclosure relates to a device designed to specifically capture samples within the target areas of a patient for specific cell collection for particular diagnosis.