公开(公告)号：US09980935B2

公开(公告)日：2018-05-29

申请号：US15597200

申请日：2017-05-17

Applicant: Center Laboratories, Inc.

Inventor： Jui-Pao Hsu ,  Guang-Tzuu Shane ,  Meng-Ju Lee ,  Yi-Ping Liao ,  Yu-Yin Yeh

IPC: A61K31/277 ,  A61K31/155 ,  A61K45/06

CPC classification number: A61K31/277 ,  A61K31/155 ,  A61K45/06 ,  A61K2300/00

Abstract: Disclosed herein are methods for treating conditions and/or disorders related to hyperglycemia. Such conditions and/or disorders related to hyperglycemia include, but are not limited to, type I, II diabetes mellitus, gestational diabetes, other forms diabetes, and disorders related thereto. In particular, the present invention relates to methods of using (R)-(+)-verapamil or a pharmaceutically acceptable salt thereof in the treatment of conditions and/or disorders related to hyperglycemia.

公开(公告)号：US10278943B2

公开(公告)日：2019-05-07

申请号：US15957956

申请日：2018-04-20

Applicant: Center Laboratories, Inc.

Inventor： Jui-Pao Hsu ,  Guang-Tzuu Shane ,  Meng-Ju Lee ,  Yi-Ping Liao ,  Yu-Yin Yeh

IPC: A61K31/277 ,  A61K31/155 ,  A61K45/06

Abstract: Disclosed herein are methods for treating conditions and/or disorders related to hyperglycemia. Such conditions and/or disorders related to hyperglycemia include, but are not limited to, type I, II diabetes mellitus, gestational diabetes, other forms diabetes, and disorders related thereto. In particular, the present invention relates to methods of using (R)-(+)-verapamil or a pharmaceutically acceptable salt thereof in the treatment of conditions and/or disorders related to hyperglycemia.

公开(公告)号：US10144704B2

公开(公告)日：2018-12-04

申请号：US15917817

申请日：2018-03-11

Applicant: Center Laboratories, Inc.

Inventor： Jui-Pao Hsu ,  Guang-Tzuu Shane ,  Yu-Yin Yeh ,  Meng-Ju Lee

IPC: C07C253/34 ,  C07C255/43

Abstract: Novel crystal forms of (R)-(+)-verapamil hydrochloride are disclosed.

公开(公告)号：US09950995B2

公开(公告)日：2018-04-24

申请号：US15521304

申请日：2015-07-13

Applicant: Center Laboratories, Inc.

Inventor： Jui-Pao Hsu ,  Guang-Tzuu Shane ,  Yu-Yin Yeh ,  Meng-Ju Lee

IPC: C07C255/00 ,  C07C255/43 ,  C07C253/34

CPC classification number: C07C255/43 ,  C07B2200/13 ,  C07C253/34

Abstract: Novel crystal forms of (R)-(−)-verapamil hydrochloride are disclosed.