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公开(公告)号:US20210113530A1
公开(公告)日:2021-04-22
申请号:US17015175
申请日:2020-09-09
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. LaBell , Piyush R. Patel
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
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公开(公告)号:US20150335750A1
公开(公告)日:2015-11-26
申请号:US14814570
申请日:2015-07-31
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. LaBell , Piyush R. Patel
IPC: A61K47/10 , A61K9/00 , A61K31/4184
CPC classification number: A61K31/4184 , A61K9/0019 , A61K9/08 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/40
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
Abstract translation: 描述了苯达莫司汀及其药学上可接受的盐和极性非质子溶剂的稳定液体制剂。
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公开(公告)号:US20170143640A1
公开(公告)日:2017-05-25
申请号:US15425421
申请日:2017-02-06
Applicant: Cephalon, Inc.
Inventor: Peter D. Brown , Anthony S. Drager
IPC: A61K9/51 , A61K9/50 , A61K31/4184 , A61K38/02 , A61K31/7088
CPC classification number: A61K9/5146 , A61K9/145 , A61K9/5031 , A61K9/5089 , A61K31/4184 , A61K31/7088 , A61K38/02 , A61K47/60 , A61K47/6935 , C07D235/16
Abstract: The present invention is directed to particles prepared via the polymerization of at least one surfactant and an isocyanate-containing compound. Pharmaceutical compositions prepared using these particles are also described.
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公开(公告)号:US20140128443A1
公开(公告)日:2014-05-08
申请号:US14151242
申请日:2014-01-09
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. LaBell , Piyush R. Patel
IPC: A61K9/08 , A61K31/4184
CPC classification number: A61K31/4184 , A61K9/0019 , A61K9/08 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/40
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
Abstract translation: 描述了苯达莫司汀及其药学上可接受的盐和极性非质子溶剂的稳定液体制剂。
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公开(公告)号:US11071789B2
公开(公告)日:2021-07-27
申请号:US16316451
申请日:2017-07-13
Applicant: CEPHALON, INC.
Inventor: Anthony S. Drager , Paritosh Wattamwar
IPC: A61K47/69 , A61K47/54 , C07H19/12 , C07H15/24 , C07H15/26 , A61K9/51 , A61K9/00 , A61K31/415 , A61K31/4184 , A61K31/704 , A61K38/00
Abstract: The disclosure provides compounds of Formula (I), wherein X, Y, and Z are defined herein. The disclosure also provides particles comprising one or more compounds described herein, compositions comprising one or more compounds or particles described herein and a pharmaceutically acceptable carrier, and methods of treating a subject in need thereof comprising administering one or more compounds, particles, or compositions described herein to the subject. X—Y—Z (I).
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公开(公告)号:US20210008035A1
公开(公告)日:2021-01-14
申请号:US16835562
申请日:2020-03-31
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. LaBell , Piyush R. Patel
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
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公开(公告)号:US10201506B2
公开(公告)日:2019-02-12
申请号:US15425421
申请日:2017-02-06
Applicant: Cephalon, Inc.
Inventor: Peter D. Brown , Anthony S. Drager
IPC: A61K9/51 , A61K38/02 , A61K9/50 , A61K31/7088 , A61K31/4184 , A61K9/14 , C07D235/16 , A61K47/60 , A61K47/69
Abstract: The present invention is directed to particles prepared via the polymerization of at least one surfactant and an isocyanate-containing compound. Pharmaceutical compositions prepared using these particles are also described.
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公开(公告)号:US09598377B2
公开(公告)日:2017-03-21
申请号:US14772540
申请日:2014-03-12
Applicant: CEPHALON, INC.
Inventor: Peter D. Brown , Anthony S. Drager
IPC: A61K9/50 , A61K47/48 , A61K31/4184 , A61K9/14 , C07D235/16
CPC classification number: A61K9/5146 , A61K9/145 , A61K9/5031 , A61K9/5089 , A61K31/4184 , A61K31/7088 , A61K38/02 , A61K47/60 , A61K47/6935 , C07D235/16
Abstract: The present invention is directed to particles prepared via the polymerization of at least one surfactant and an isocyanate-containing compound. Pharmaceutical compositions prepared using these particles are also described.
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公开(公告)号:US20140206733A1
公开(公告)日:2014-07-24
申请号:US14221422
申请日:2014-03-21
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. Labell , Piyush R. Patel
IPC: A61K31/4184 , A61K47/10
CPC classification number: A61K31/4184 , A61K9/0019 , A61K9/08 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/40
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
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公开(公告)号:US20140080881A1
公开(公告)日:2014-03-20
申请号:US14084768
申请日:2013-11-20
Applicant: Cephalon, Inc.
Inventor: Anthony S. Drager , Rachel Y. LaBell , Piyush R. Patel
IPC: A61K31/4184
CPC classification number: A61K31/4184 , A61K9/0019 , A61K9/08 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/40
Abstract: Stable liquid formulations of bendamustine, and pharmaceutically acceptable salts thereof, and polar aprotic solvents, are described.
Abstract translation: 描述了苯达莫司汀及其药学上可接受的盐和极性非质子溶剂的稳定液体制剂。
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