公开(公告)号：US20230055359A1

公开(公告)日：2023-02-23

申请号：US17821093

申请日：2022-08-19

Applicant: Cepheid

Inventor： Amish Shah ,  Marissa Lee ,  Jessica Koay ,  Richard J Casler, JR.

IPC: G01R31/26 ,  G01N21/76 ,  B01L7/00 ,  G01N35/00

Abstract: Systems and methods for monitoring, characterizing and controlling operation of LEDs are provided herein. Methods includes measuring a voltage across the LED, and correlating the voltage to a junction temperature of the LED. This correlation can be used to improve operation of the LED by increasing the signal to noise ratio of the LED signal, characterize the LED by comparing to an I-V curve, control LED operation to compensate for LED degradation and avoid crosstalk, and/or to generally improve performance and life expectancy of the LED. Improved performance of the LED can include stabilizing the photon output during performance of an assay to provide a desired dye reporter signal required for the assay and/or reducing an intra-shot during of the LED output during the assay. System and device with control units configured to perform these methods are also described herein.