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公开(公告)号:US5821371A
公开(公告)日:1998-10-13
申请号:US470788
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
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公开(公告)号:US5672709A
公开(公告)日:1997-09-30
申请号:US470789
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08 , C07F7/10
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
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公开(公告)号:US5929247A
公开(公告)日:1999-07-27
申请号:US470790
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
摘要翻译: 本发明涉及治疗活性的氮杂环或氮杂双环化合物,其制备方法和包含该化合物的药物组合物。 新型化合物可用于治疗由毒蕈碱胆碱能系统功能障碍引起的中枢神经系统疾病。
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公开(公告)号:US5665745A
公开(公告)日:1997-09-09
申请号:US470791
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08 , C07D417/14
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
摘要翻译: 本发明涉及治疗活性的氮杂环或氮杂双环化合物,其制备方法和包含该化合物的药物组合物。 新型化合物可用于治疗由毒蕈碱胆碱能系统功能障碍引起的中枢神经系统疾病。
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公开(公告)号:US5646289A
公开(公告)日:1997-07-08
申请号:US468481
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward , Charles H. Mitch
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
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公开(公告)号:US5821370A
公开(公告)日:1998-10-13
申请号:US470787
申请日:1995-06-06
申请人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward
发明人: Charles A. Alt , Leander Merritt , Gary A. Rhodes , Roger L. Robey , Eldon E. Van Meter , John S. Ward
IPC分类号: C07D285/06 , A61K31/41 , A61K31/425 , A61K31/433 , A61K31/435 , A61K31/445 , A61K31/46 , A61P1/00 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D285/10 , C07D417/12 , C07D451/02 , C07D451/04 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
CPC分类号: C07D285/10 , C07D417/12 , C07D451/06 , C07D453/02 , C07D453/06 , C07D471/04 , C07D471/08 , C07D487/08
摘要: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
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公开(公告)号:US5292962A
公开(公告)日:1994-03-08
申请号:US989291
申请日:1992-12-11
IPC分类号: C07C43/23 , C07C217/48 , C07D317/54 , C07D317/50 , C07D317/52
CPC分类号: C07C43/23 , C07C217/48 , C07D317/54
摘要: Intermediates to 1-phenyl-3-naphthalenyloxypropanamines which selectively inhibit serotonin uptake and are useful for treating a variety of disorders linked to decreased neurotransmission of serotonin in mammals.
摘要翻译: 选择性抑制5-羟色胺摄取的1-苯基-3-萘氧基丙胺的中间体,可用于治疗与哺乳动物中5-羟色胺的神经传递减少有关的各种障碍。
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