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1.发明授权Method for producing a time-resolved series of 3D magnetic resonance angiograms during the first passage of contrast agent 失效在造影剂第一次通过期间产生时间分辨系列的3D磁共振血管造影的方法
公开(公告)号：US5713358A
公开(公告)日：1998-02-03
申请号：US622718
申请日：1996-03-26
IPC分类号： G01R33/28 , A61B5/055 , G01R33/48 , G01R33/54 , G01R33/561 , G01R33/563
CPC分类号： G01R33/5619 , G01R33/5635 , G01R33/56325
摘要： A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions.
摘要翻译： 使用3D快速梯度回波脉冲序列进行受试者的动态MRA研究。 通过以比k空间的外围区域更高的速率对k空间的中心区域进行采样来增加所得到的一系列重构图像的帧速率。 使用来自外围k空间区域的时间上最近的采样，在中心k空间区域的每个采样处重构图像帧。
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2.发明授权
公开(公告)号：US5285158A
公开(公告)日：1994-02-08
申请号：US926658
申请日：1992-08-06
IPC分类号： A61B5/055 , G01R33/48 , G01R33/563 , G01R33/70
CPC分类号： G01R33/563
摘要： An angiogram is produced using NMR fast pulse sequences in which the views are acquired in shots preceded by a preparatory pulse sequence. Each shot is acquired twice with differing preparatory pulse sequences and the resulting NMR data is subtracted to null the stationary tissues in the reconstructed image.
摘要翻译： 使用NMR快速脉冲序列产生血管造影图像，其中在预备脉冲序列之前的拍摄中获取视图。 每个镜头用不同的准备脉冲序列获得两次，并且所得到的NMR数据被减去以使重建图像中的静止组织无效。
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3.发明授权Digital subtraction magnetic resonance angiography with image artifact suppression 失效数字减影磁共振血管造影与图像伪影抑制
公开(公告)号：US5881728A
公开(公告)日：1999-03-16
申请号：US686795
申请日：1996-07-26
IPC分类号： G01R33/28 , A61B5/055 , G01R33/561 , G01R33/563
CPC分类号： G01R33/561 , G01R33/563 , G01R33/281 , G01R33/5619 , G01R33/56308
摘要： A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Artifacts caused by variations in signal strength as the contrast agent enters the region of interest are reduced by renormalizing the acquired data. 2D image frames are reconstructed using planes passing near the center of k-space to enable the operator to select which 3D data sets should be used to reconstruct diagnostic images.
摘要翻译： 使用3D快速梯度回波脉冲序列进行受试者的动态MRA研究。 通过以比k空间的外围区域更高的速率对k空间的中心区域进行采样来增加所得到的一系列重构图像的帧速率。 造影剂进入感兴趣区域的信号强度变化引起的人造物通过重新归一化所获取的数据而减少。 使用通过k空间中心附近的平面来重构2D图像帧，以使操作者能够选择哪些3D数据集应用于重构诊断图像。
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公开(公告)号：US5204627A
公开(公告)日：1993-04-20
申请号：US669143
申请日：1991-03-14
IPC分类号： G01R33/56 , G01R33/563
CPC分类号： G01R33/563 , G01R33/56
摘要： A magnetic resonance angiogram is produced by projecting a 3D array of motion sensitized NMR data. A mask which locates the vessels in the 3D array is produced by thresholding the NMR data, and this mask is combined with the 3D NMR data set to exclude signals produced by surrounding stationary tissues. An integration projection technique is used to produce the angiogram from the masked data set.
摘要翻译： 通过投影运动敏化NMR数据的3D阵列产生磁共振血管造影。 通过对NMR数据进行阈值产生定位3D阵列中的血管的掩模，并将该掩模与3D NMR数据组合以排除由周围的静止组织产生的信号。 使用积分投影技术从掩蔽的数据集中产生血管造影。
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公开(公告)号：US5031624A
公开(公告)日：1991-07-16
申请号：US568938
申请日：1990-08-17
IPC分类号： A61B5/055 , G01R33/48 , G01R33/563 , G01R33/567
CPC分类号： G01R33/56316 , G01R33/5673
摘要： An NMR angiogram is produced using a line scan data acquisition. Each line of NMR data is acquired twice, once with a velocity sensitizing gradient having a positive first moment and once with a velocity sensitizing gradient having a negative first moment. The two signals from the acquisition are subtracted to cancel signals from stationary spins while enhancing signals from flowing spins. The magnitude of the velocity sensitizing gradient moment is changed during the cardiac cycle so that aliasing does not occur at high blood velocities and the signal strength does not drop too low at low blood velocities. An angiogram is produced by reconstructing an image from line scan data acquired from a series of slices.
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6.发明授权Measurement of flow using a complex difference method of magnetic resonance imaging 失效使用磁共振成像的复差法进行流量测量
公开(公告)号：US5408180A
公开(公告)日：1995-04-18
申请号：US107110
申请日：1993-08-13
IPC分类号： A61B5/055 , G01F1/716 , G01N24/00 , G01R33/563 , G01V3/00
CPC分类号： G01R33/56308 , G01F1/716 , G01R33/56316
摘要： NMR image data is acquired with velocity encoding gradients applied and both a phase difference image array and a complex difference image array are produced. A flow image is produced from the complex difference image array after it is corrected for spin saturation effects and calibrated using information derived from the phase difference image array. Total blood flow through vessels can be measured from the flow image.
摘要翻译： 利用应用速度编码梯度获得NMR图像数据，并且产生相位差图像阵列和复差分图像阵列。 在对自旋饱和效应进行校正之后，从复差分图像阵列产生流动图像，并使用从相位差图像阵列导出的信息进行校准。 可以从流动图像中测量通过血管的总血流量。
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7.发明授权Contrast enhanced MRA with highly constrained backprojection reconstruction using phase contrast composite image 有权使用相位对比合成图像对比增强MRA和高度受限的反投影重建公开(公告)号：US07991452B2
公开(公告)日：2011-08-02
申请号：US11966237
申请日：2007-12-28
IPC分类号： A61B5/055
CPC分类号： G01R33/561 , G01R33/4824 , G01R33/5601 , G01R33/56308 , G01R33/56316 , G01R33/5635 , G01R33/56509
摘要： Mask projection views are obtained prior to the arrival of a contrast agent during a dynamic contrast enhanced MRA study. After the arrival of the contrast agent, a set of undersampled contrast enhanced projection views are obtained for each of a plurality of time frames. Corresponding mask projection views are subtracted from the contrast enhanced projection views to provide sparse contrast enhanced projection view sets. A phase contrast scan of a region of interest is performed prior to or after the arrival of the contrast agent. The phase contrast image is used as a composite image in a HYPR reconstruction of the sparse projection view sets to produce first pass contrast enhanced images. Iterative HYPR reconstructions can also be performed to remove venous information from the reconstructed images.
摘要翻译： 在动态造影增强MRA研究期间，在造影剂到达之前获得掩模投影视图。 在造影剂到达之后，对于多个时间帧中的每一个获得一组欠采样的对比度增强的投影视图。 从对比度增强的投影视图中减去相应的掩模投影视图，以提供稀疏对比度增强的投影视图集。 感兴趣区域的相位扫描在造影剂到达之前或之后进行。 相位对比图像用作稀疏投影视图集的HYPR重建中的合成图像，以产生第一遍对比度增强图像。 还可以进行迭代HYPR重建以从重建的图像中去除静脉信息。
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8.发明申请Contrast Enhanced MRA With Highly Constrained Backprojection Reconstruction Using Phase Contrast Composite Image 有权对比使用相位对比复合图像的高约束反投影重建的增强MRA公开(公告)号：US20100286504A1
公开(公告)日：2010-11-11
申请号：US11966237
申请日：2007-12-28
IPC分类号： A61B5/055
CPC分类号： G01R33/561 , G01R33/4824 , G01R33/5601 , G01R33/56308 , G01R33/56316 , G01R33/5635 , G01R33/56509
摘要： Mask projection views are obtained prior to the arrival of a contrast agent during a dynamic contrast enhanced MRA study. After the arrival of the contrast agent, a set of undersampled contrast enhanced projection views are obtained for each of a plurality of time frames. Corresponding mask projection views are subtracted from the contrast enhanced projection views to provide sparse contrast enhanced projection view sets. A phase contrast scan of a region of interest is performed prior to or after the arrival of the contrast agent. The phase contrast image is used as a composite image in a HYPR reconstruction of the sparse projection view sets to produce first pass contrast enhanced images. Iterative HYPR reconstructions can also be performed to remove venous information from the reconstructed images.
摘要翻译： 在动态造影增强MRA研究期间，在造影剂到达之前获得掩模投影视图。 在造影剂到达之后，对于多个时间帧中的每一个获得一组欠采样的对比度增强的投影视图。 从对比度增强的投影视图中减去相应的掩模投影视图，以提供稀疏对比度增强的投影视图集。 感兴趣区域的相位扫描在造影剂到达之前或之后进行。 相位对比图像用作稀疏投影视图集的HYPR重建中的合成图像，以产生第一遍对比度增强图像。 还可以进行迭代HYPR重建以从重建的图像中去除静脉信息。
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9.发明授权Dual resolution acquisition of magnetic resonance angiography data with vessel segmentation 有权双分辨率采集磁共振血管造影数据与血管分割公开(公告)号：US06556856B1
公开(公告)日：2003-04-29
申请号：US09664152
申请日：2000-09-18
申请人： Charles A. Mistretta , Thomas M. Grist , Yousef Mazahheri , Timothy J. Carroll , Jiang Du , Walter Block
发明人： Charles A. Mistretta , Thomas M. Grist , Yousef Mazahheri , Timothy J. Carroll , Jiang Du , Walter Block
IPC分类号： A61B5055
CPC分类号： G01R33/5635 , G01R33/5619
摘要： A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of low resolution NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Additional, high spatial resolution NMR image data is acquired in a subsequent steady-state phase of the examination. The low resolution NMR image is segmented and masked to depict only arteries, and the central k-space region of this data is combined with the peripheral k-space data portion of the high resolution NMR data to produce one or more images.
摘要翻译： 使用对比度增强方法获得磁共振血管造影（MRA），其中在检查的时间分辨阶段期间快速获取一系列低分辨NMR图像，其中对比剂推注首先通过动脉和静脉。 此外，在随后的检查的稳态阶段获取高空间分辨率NMR图像数据。 低分辨率NMR图像被分割和掩蔽以仅描绘动脉，并且该数据的中心k空间区域与高分辨率NMR数据的外围k空间数据部分组合以产生一个或多个图像。
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公开(公告)号：US06381486B1
公开(公告)日：2002-04-30
申请号：US09314227
申请日：1999-05-18
IPC分类号： A61B505
CPC分类号： G01R33/5635 , G01R33/5619
摘要： A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of low resolution NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Additional, high resolution NMR image data is acquired in a subsequent steady-state phase of the examination from which a high resolution NMR image is reconstructed. Segmentation of arteries, veins and background in the high resolution image is performed using information in the low resolution NMR images.
摘要翻译： 使用对比度增强方法获得磁共振血管造影（MRA），其中在检查的时间分辨阶段期间快速获取一系列低分辨NMR图像，其中对比剂推注首先通过动脉和静脉。 另外，高分辨率NMR图像数据在随后的重建的高分辨率NMR图像的检查的稳态阶段获得。 使用低分辨率NMR图像中的信息来执行高分辨率图像中的动脉，静脉和背景的分割。
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