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    Signal Processing with Fast S-Transforms
    2.
    发明申请
    Signal Processing with Fast S-Transforms 有权
    信号处理与快速S变换

    公开(公告)号：US20100191792A1

    公开(公告)日：2010-07-29

    申请号：US12482237

    申请日：2009-06-10

    申请人： Robert Brown ,  M. Louis Lauzon ,  Richard Frayne

    发明人： Robert Brown ,  M. Louis Lauzon ,  Richard Frayne

    IPC分类号： G06F17/14

    CPC分类号： G06F17/148

    摘要： The ability to examine the frequency content of a signal is critical in a variety of fields, and many techniques have been proposed to fill this need, including the Fourier and wavelet family of transforms. One of these, the S-transform, is a Fourier based transform that provides simultaneous time and frequency information similar to the wavelet transform but uses sinusoidal basis functions to produce true frequency and globally referenced phase measurements. It has been shown to be useful in several medical imaging applications but its use is limited due to high computational requirements of the original, continuous form. The described embodiments include a general framework for describing linear time-frequency transforms, using the Fourier, wavelet and S-transforms as examples. As an illustration of the utility of this formalism, a fast discrete S-transform algorithm is developed that has the same computational complexity as the fast Fourier transform.

    摘要翻译： 检查信号的频率内容的能力在各种领域中是至关重要的，并且已经提出了许多技术来满足这种需要，包括傅里叶变换和小波变换族。 其中之一，S变换是基于傅立叶的变换，其提供类似于小波变换的同时时间和频率信息，但是使用正弦基函数来产生真实的频率和全局参考相位测量。 已经显示在几种医学成像应用中是有用的，但是由于原始连续形式的高计算要求，其使用受到限制。 所描述的实施例包括用于描述线性时间 - 频率变换的一般框架，使用傅立叶，小波和S变换作为示例。 作为这种形式主义效用的一个例证，开发了具有与快速傅立叶变换相同计算复杂度的快速离散S变换算法。

    Real time in vivo measurement of temperature changes with contrast enhanced NMR imaging
    3.
    发明授权
    Real time in vivo measurement of temperature changes with contrast enhanced NMR imaging 失效
    温度变化的实时体内测量与对比度增强的核磁共振成像

    公开(公告)号：US06377834B1

    公开(公告)日：2002-04-23

    申请号：US09557263

    申请日：2000-04-24

    申请人： Yong Zhou ,  Richard Frayne

    发明人： Yong Zhou ,  Richard Frayne

    IPC分类号： A61B5055

    CPC分类号： G01R33/4804 ,  A61B5/015 ,  A61B5/055 ,  G01R33/281

    摘要： NMR images indicative of thermal changes in tissues undergoing therapy are produced using a gradient-recalled echo pulse sequence. Prior to therapy a contrast agent which shortens spin T1 relaxation time is injected into the patient and a reference phase image indicative of proton chemical shift is acquired. Temperature maps are produced in real-time as the therapy is subsequently performed by repeatedly acquiring NMR data, reconstructing measurement phase images and subtracting the reference phase image. The temporal rate at which the temperature maps are produced is increased by segmenting k-space and acquiring less than all the segments during each repetition.

    摘要翻译： 使用梯度回波脉冲序列产生指示进行治疗的组织中热变化的NMR图像。 在治疗之前，将自旋T1弛豫时间缩短的造影剂注射到患者体内，并获得指示质子化学位移的参考相图像。 温度图实时产生，随后通过重复获取NMR数据，重建测量相位图像和减去参考相位图像进行治疗。 通过在每个重复期间分割k空间和获取小于所有段来增加产生温度映射的时间速率。

    Digital subtraction magnetic resonance angiography with image artifact suppression
    6.
    发明授权
    Digital subtraction magnetic resonance angiography with image artifact suppression 失效
    数字减影磁共振血管造影与图像伪影抑制

    公开(公告)号：US5881728A

    公开(公告)日：1999-03-16

    申请号：US686795

    申请日：1996-07-26

    申请人： Charles A. Mistretta ,  Thomas M. Grist ,  Richard Frayne ,  Frank Korosec

    发明人： Charles A. Mistretta ,  Thomas M. Grist ,  Richard Frayne ,  Frank Korosec

    IPC分类号： G01R33/28 ,  A61B5/055 ,  G01R33/561 ,  G01R33/563

    CPC分类号： G01R33/561 ,  G01R33/563 ,  G01R33/281 ,  G01R33/5619 ,  G01R33/56308

    摘要： A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Artifacts caused by variations in signal strength as the contrast agent enters the region of interest are reduced by renormalizing the acquired data. 2D image frames are reconstructed using planes passing near the center of k-space to enable the operator to select which 3D data sets should be used to reconstruct diagnostic images.

    摘要翻译： 使用3D快速梯度回波脉冲序列进行受试者的动态MRA研究。 通过以比k空间的外围区域更高的速率对k空间的中心区域进行采样来增加所得到的一系列重构图像的帧速率。 造影剂进入感兴趣区域的信号强度变化引起的人造物通过重新归一化所获取的数据而减少。 使用通过k空间中心附近的平面来重构2D图像帧，以使操作者能够选择哪些3D数据集应用于重构诊断图像。

    Signal processing with fast S-transforms
    7.
    发明授权
    Signal processing with fast S-transforms 有权
    信号处理快速S变换

    公开(公告)号：US08458240B2

    公开(公告)日：2013-06-04

    申请号：US12482237

    申请日：2009-06-10

    申请人： Robert Brown ,  M. Louis Lauzon ,  Richard Frayne

    发明人： Robert Brown ,  M. Louis Lauzon ,  Richard Frayne

    IPC分类号： G06F17/14 ,  G06F15/00

    CPC分类号： G06F17/148

    摘要： The ability to examine the frequency content of a signal is critical in a variety of fields, and many techniques have been proposed to fill this need, including the Fourier and wavelet family of transforms. One of these, the S-transform, is a Fourier based transform that provides simultaneous time and frequency information similar to the wavelet transform but uses sinusoidal basis functions to produce true frequency and globally referenced phase measurements. It has been shown to be useful in several medical imaging applications but its use is limited due to high computational requirements of the original, continuous form. The described embodiments include a general framework for describing linear time-frequency transforms, using the Fourier, wavelet and S-transforms as examples. As an illustration of the utility of this formalism, a fast discrete S-transform algorithm is developed that has the same computational complexity as the fast Fourier transform.

    摘要翻译： 检查信号的频率内容的能力在各种领域中是至关重要的，并且已经提出了许多技术来满足这种需要，包括傅里叶变换和小波变换族。 其中之一，S变换是基于傅立叶的变换，其提供类似于小波变换的同时时间和频率信息，但是使用正弦基函数来产生真实的频率和全局参考相位测量。 已经显示在几种医学成像应用中是有用的，但是由于原始连续形式的高计算要求，其使用受到限制。 所描述的实施例包括用于描述线性时间 - 频率变换的一般框架，使用傅立叶，小波和S变换作为示例。 作为这种形式主义效用的一个例证，开发了具有与快速傅立叶变换相同计算复杂度的快速离散S变换算法。

    Gated time-resolved contrast-enhanced 3D MR angiography
    9.
    发明授权
    Gated time-resolved contrast-enhanced 3D MR angiography 失效
    门控时间分辨对比度增强3D MR血管造影

    公开(公告)号：US5830143A

    公开(公告)日：1998-11-03

    申请号：US787181

    申请日：1997-01-21

    申请人： Charles M. Mistretta ,  Frank R. Korosec ,  Thomas M. Grist ,  Richard Frayne

    发明人： Charles M. Mistretta ,  Frank R. Korosec ,  Thomas M. Grist ,  Richard Frayne

    IPC分类号： G01R33/28 ,  A61B5/055 ,  G01R33/48 ,  G01R33/561 ,  G01R33/563 ,  G01R33/567 ,  H61B5/055

    CPC分类号： G01R33/561 ,  G01R33/281 ,  G01R33/563 ,  G01R33/56308 ,  G01R33/567

    摘要： A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence that employs a non-selective RF excitation pulse. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. The acquisition is gated using a cardiac trigger signal and the central region of k-space is acquired during diastole and the peripheral regions of k-space are acquired during systole. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions. Two of the image frames are subtracted to form an MR angiogram.

    摘要翻译： 使用采用非选择性RF激励脉冲的3D快速梯度回波脉冲序列来执行对象的动态MRA研究。 通过以比k空间的外围区域更高的速率对k空间的中心区域进行采样来增加所得到的一系列重构图像的帧速率。 使用心脏触发信号门控获取，并且在舒张期期间获取k空间的中心区域，并且在收缩期间获取k空间的周边区域。 使用来自外围k空间区域的时间上最近的采样，在中心k空间区域的每个采样处重构图像帧。 减去两个图像帧以形成MR血管造影图。