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公开(公告)号：US08888498B2
公开(公告)日：2014-11-18
申请号：US12792073
申请日：2010-06-02
CPC分类号： G01N21/4785 , A61B5/00 , A61B2560/0228 , A61B2560/0233 , G01N21/59 , G01N2201/08 , G01N2201/127 , G09B23/285 , G09B23/286
摘要： A method for producing a multilayer tissue phantom involves successively forming at least two layers, each layer formed by depositing a viscous flowable material over a supporting element or over a previously formed layer of the phantom supported by the supporting element, selectively redistributing the material while material is solidifying to control a thickness distribution of the layer, and allowing the material to solidify sufficiently to apply a next layer. The supporting element supports the material in 2 or 3 directions and effectively molds a lumen of the tissue. The neighboring layers are of different composition and of chosen thickness to provide desired optical properties and mechanical properties of the phantom. The phantom may have selected attenuation and backscattering properties to mimic tissues for optical coherence tomography imaging.
摘要翻译： 用于制造多层组织体模的方法包括连续地形成至少两层，每层通过在支撑元件上沉积粘性可流动材料形成，或者由预先形成的由支撑元件支撑的体模层形成，选择性地重新分配材料，同时材料 正在凝固以控制该层的厚度分布，并允许该材料足够固化以施加下一层。 支撑元件以2或3个方向支撑材料，并有效地模制组织的内腔。 相邻的层具有不同的组成和选定的厚度以提供所需的光学性质和体模的机械性能。 幻影可以选择衰减和后向散射特性来模拟组织用于光学相干断层成像。
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公开(公告)号：US20110062318A1
公开(公告)日：2011-03-17
申请号：US12792073
申请日：2010-06-02
CPC分类号： G01N21/4785 , A61B5/00 , A61B2560/0228 , A61B2560/0233 , G01N21/59 , G01N2201/08 , G01N2201/127 , G09B23/285 , G09B23/286
摘要： A method for producing a multilayer tissue phantom involves successively forming at least two layers, each layer formed by depositing a viscous flowable material over a supporting element or over a previously formed layer of the phantom supported by the supporting element, selectively redistributing the material while material is solidifying to control a thickness distribution of the layer, and allowing the material to solidify sufficiently to apply a next layer. The supporting element supports the material in 2 or 3 directions and effectively molds a lumen of the tissue. The neighbouring layers are of different composition and of chosen thickness to provide desired optical properties and mechanical properties of the phantom. The phantom may have selected attenuation and backscattering properties to mimic tissues for optical coherence tomography imaging.
摘要翻译： 用于制造多层组织体模的方法包括连续地形成至少两层，每层通过在支撑元件上沉积粘性可流动材料形成，或者由预先形成的由支撑元件支撑的体模层形成，选择性地重新分配材料，同时材料 正在凝固以控制该层的厚度分布，并允许该材料足够固化以施加下一层。 支撑元件以2或3个方向支撑材料，并有效地模制组织的内腔。 相邻的层具有不同的组成和选定的厚度以提供所需的光学性质和体模的机械性能。 幻影可以选择衰减和后向散射特性来模拟组织用于光学相干断层成像。
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公开(公告)号：US07428086B2
公开(公告)日：2008-09-23
申请号：US11498875
申请日：2006-08-04
申请人： Marc L. Dufour , Guy Lamouche , Bruno Gauthier
发明人： Marc L. Dufour , Guy Lamouche , Bruno Gauthier
IPC分类号： G02B26/08
CPC分类号： G02B26/06 , G02B17/023 , G02B26/0816
摘要： A scanning optical delay line includes an optical path element that rotates about its central axis, such that a face is intermittently incident a beam of light to be optically delayed. When the beam is not incident the face, it is reflected onto a reinsertion line which provides a second opportunity for the beam to intersect the optical path element. The optical path element may include one or more parallelogram prisms, or parallel reflective surfaces to provide a substantially linear optical path length variation during the scan, which is produced by the rotation of the optical path element. A highly linear part of the rotation can be maximally used providing a high duty cycle, high linearity scanning optical delay line that permits high quality, high data rate applications.
摘要翻译： 扫描光学延迟线包括围绕其中心轴线旋转的光路元件，使得面部间歇地入射到光学延迟的光束。 当光束没有入射到面部时，它被反射到重新插入线上，这为光束与光路元件相交提供了第二次机会。 光路元件可以包括一个或多个平行四边形棱镜或平行的反射表面，以在扫描期间提供通过光路元件的旋转产生的基本线性的光程长度变化。 可以最大程度地利用旋转的高度线性部分，提供允许高质量，高数据速率应用的高占空比，高线性扫描光学延迟线。
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公开(公告)号：US20070091401A1
公开(公告)日：2007-04-26
申请号：US11498875
申请日：2006-08-04
申请人： Marc Dufour , Guy Lamouche , Bruno Gauthler
发明人： Marc Dufour , Guy Lamouche , Bruno Gauthler
IPC分类号： G02B26/08
CPC分类号： G02B26/06 , G02B17/023 , G02B26/0816
摘要： A scanning optical delay line includes an optical path element that rotates about its central axis, such that a face is intermittently incident a beam of light to be optically delayed. When the beam is not incident the face, it is reflected onto a reinsertion line which provides a second opportunity for the beam to intersect the optical path element. The optical path element may include one or more parallelogram prisms, or parallel reflective surfaces to provide a substantially linear optical path length variation during the scan, which is produced by the rotation of the optical path element. A highly linear part of the rotation can be maximally used providing a high duty cycle, high linearity scanning optical delay line that permits high quality, high data rate applications.
摘要翻译： 扫描光学延迟线包括围绕其中心轴线旋转的光路元件，使得面部间歇地入射到光学延迟的光束。 当光束没有入射到面部时，它被反射到重新插入线上，这为光束与光路元件相交提供了第二次机会。 光路元件可以包括一个或多个平行四边形棱镜或平行的反射表面，以在扫描期间提供通过光路元件的旋转产生的基本线性的光程长度变化。 可以最大程度地利用旋转的高度线性部分，提供允许高质量，高数据速率应用的高占空比，高线性扫描光学延迟线。
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公开(公告)号：US20070091400A1
公开(公告)日：2007-04-26
申请号：US11254748
申请日：2005-10-21
申请人： Marc Dufour , Guy Lamouche , Bruno Gauthier
发明人： Marc Dufour , Guy Lamouche , Bruno Gauthier
IPC分类号： G02B26/08
CPC分类号： G02B17/023 , G02B26/06
摘要： A scanning optical delay line includes an optical path element that rotates about its central axis, such that a face is intermittently incident a beam of light to be optically delayed. When the beam is not incident the face, it is reflected onto a reinsertion line which provides a second opportunity for the beam to intersect the optical path element. The optical path element may include one or more parallelogram prisms, or parallel reflective surfaces to provide a substantially linear optical path length variation during the scan, which is produced by the rotation of the optical path element. A highly linear part of the rotation can be maximally used providing a high duty cycle, high linearity scanning optical delay line that permits high quality, high data rate applications.
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6.发明授权Method and system for determining material properties using ultrasonic attenuation 有权使用超声波衰减确定材料性质的方法和系统公开(公告)号：US07353709B2
公开(公告)日：2008-04-08
申请号：US11174496
申请日：2005-07-06
IPC分类号： G01N29/11
CPC分类号： G01N29/11 , G01N29/2412 , G01N29/2418 , G01N29/30 , G01N29/348 , G01N29/4418 , G01N29/4436 , G01N29/46 , G01N29/48 , G01N2291/0421 , G01N2291/0422 , G01N2291/0423 , G01N2291/102
摘要： A method and system is disclosed for determining a property of an object by measuring ultrasonic attenuation. With the proposed method, a measured ultrasonic interaction signal of the object is compared with a reference signal produced using the same generation and detection setup, but using a reference part. The reference ultrasonic signal has low attenuation, and exhibits equivalent diffraction properties as the object, with respect to a broadband ultrasonic pulse. The difference is attributable to the attenuation of the object. The attenuation as a function of frequency, the attenuation spectrum, is fitted to a model to obtain a parameter useful for identifying one of the many properties of an object that varies with ultrasonic attenuation.
摘要翻译： 公开了一种通过测量超声波衰减来确定物体的性质的方法和系统。 利用所提出的方法，将物体的测量超声波相互作用信号与使用相同的生成和检测设置产生的参考信号进行比较，但使用参考部分。 相对于宽带超声脉冲，参考超声信号具有低衰减，并且表现出与物体相当的衍射特性。 差异归因于物体的衰减。 作为频率的函数的衰减衰减谱被拟合到模型中以获得用于识别通过超声衰减而变化的对象的许多属性之一的参数。
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7.发明申请Method and system for determining material properties using ultrasonic attenuation 有权使用超声波衰减确定材料性质的方法和系统公开(公告)号：US20070006651A1
公开(公告)日：2007-01-11
申请号：US11174496
申请日：2005-07-06
IPC分类号： G01N29/04
CPC分类号： G01N29/11 , G01N29/2412 , G01N29/2418 , G01N29/30 , G01N29/348 , G01N29/4418 , G01N29/4436 , G01N29/46 , G01N29/48 , G01N2291/0421 , G01N2291/0422 , G01N2291/0423 , G01N2291/102
摘要： A method and system is disclosed for determining a property of an object by measuring ultrasonic attenuation. With the proposed method, a measured ultrasonic interaction signal of the object is compared with a reference signal produced using the same generation and detection setup, but using a reference part. The reference ultrasonic signal has low attenuation, and exhibits equivalent diffraction properties as the object, with respect to a broadband ultrasonic pulse. The difference is attributable to the attenuation of the object. The attenuation as a function of frequency, the attenuation spectrum, is fitted to a model to obtain a parameter useful for identifying one of the many properties of an object that varies with ultrasonic attenuation.
摘要翻译： 公开了一种通过测量超声波衰减来确定物体的性质的方法和系统。 利用所提出的方法，将物体的测量超声波相互作用信号与使用相同的生成和检测设置产生的参考信号进行比较，但使用参考部分。 相对于宽带超声脉冲，参考超声信号具有低衰减，并且表现出与物体相当的衍射特性。 差异归因于物体的衰减。 作为频率的函数的衰减衰减谱被拟合到模型中以获得用于识别通过超声衰减而变化的对象的许多属性之一的参数。
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8.发明授权Apparatus and method for evaluating the physical properties of a sample using ultrasonics 失效使用超声波评估样品的物理性质的装置和方法公开(公告)号：US06532821B2
公开(公告)日：2003-03-18
申请号：US09901659
申请日：2001-07-11
申请人： Guy Lamouche , Andre Moreau , Martin Lord , Daniel Levesque
发明人： Guy Lamouche , Andre Moreau , Martin Lord , Daniel Levesque
IPC分类号： G01N2916
CPC分类号： G01N29/2418 , G01N29/38 , G01N29/42 , G01N29/4418 , G01N29/4472 , G01N2291/015 , G01N2291/0289
摘要： A method is disclosed for evaluating the physical properties of a sample, for example, the grain size in a polycrystalline material. An ultrasound field is generated in a local region of the sample with a non-contact source, such as a pulsed laser, such that the generated ultrasound diffuses away from said local region. After waiting until the generated ultrasound field has reached a diffusion regime, the resulting ultrasound field is measured with a non-contact detector. Parameters are adjusted in a mathematical model describing the predicted behaviour of the ultrasound field in the diffusion regime to fit the detected ultrasound field to the mathematical model. In this way, parameters dependent on the physical properties of the sample, such as the diffusion coefficient and absorption coefficient, can be derived. The grain size, for example, can be estimated from these parameters preferably by calibrating the diffusion coefficient to grain size.
摘要翻译： 公开了用于评估样品的物理性质的方法，例如多晶材料中的晶粒尺寸。 在具有非接触源（例如脉冲激光）的样品的局部区域中产生超声波场，使得所产生的超声波从所述局部区域扩散。 在等待直到产生的超声波场达到扩散方式后，用非接触检测器测量所得的超声波场。 在描述超声场在扩散状态中的预测行为的数学模型中调整参数以将检测到的超声场拟合到数学模型。 以这种方式，可以得出取决于样品的物理性质的参数，如扩散系数和吸收系数。 例如，可以从这些参数估计晶粒尺寸，优选通过将扩散系数校准为晶粒尺寸。
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