公开(公告)号：US20070065826A1

公开(公告)日：2007-03-22

申请号：US10570594

申请日：2004-09-06

申请人： Chikako Takatoh ,  Kazuyoshi Takeda ,  Hirokazu Sato ,  Takayuki Saito ,  Takuya Matsumoto ,  Tomoji Kawai

发明人： Chikako Takatoh ,  Kazuyoshi Takeda ,  Hirokazu Sato ,  Takayuki Saito ,  Takuya Matsumoto ,  Tomoji Kawai

IPC分类号： C12Q1/68 ,  C09B47/04 ,  C07D487/22 ,  C07H21/04

CPC分类号： C12Q1/6825 ,  C12Q2563/173

摘要： A cationic dye compound having novel uses, the cationic dye compound being capable of conveniently and rapidly detecting a nucleic acid double strand, and a detection method using the cationic dye compound are provided. This invention relates to a cationic dye compound for detecting a nucleic acid double strand, comprising: a cation group and a chromophore coupled to said cation group, wherein said chromophore has a heteropolycyclic structure containing a nitrogen atom and said cationic dye compound is capable of helically binding onto said nucleic acid double strand.

摘要翻译： 提供了具有新用途的阳离子染料化合物，能够方便快速地检测核酸双链的阳离子染料化合物和使用阳离子染料化合物的检测方法。 本发明涉及一种用于检测核酸双链的阳离子染料化合物，包括：阳离子基团和与所述阳离子基团偶联的发色团，其中所述发色团具有含有氮原子的杂多环结构，所述阳离子染料化合物能够螺旋 结合到所述核酸双链上。