公开(公告)号：US20230227507A1

公开(公告)日：2023-07-20

申请号：US18008797

申请日：2021-06-10

Applicant: Chr. Hansen A/S

Inventor： Thomas Janzen ,  Ditte Ellegaard Christiansen ,  Mia Vissing Mikkelsen ,  Thomas Eckhardt

IPC: C07K14/315 ,  A23C19/032 ,  C12N1/20

CPC classification number: C07K14/315 ,  A23C19/0323 ,  C12N1/205 ,  A23Y2240/41 ,  C12R2001/46

Abstract: The present invention provides a method of increasing nisin production in nisin-producing Lactococcus lactis by inactivating the phage infection protein Pip. The invention also provides nisin-producing Lactococcus lactis in which the phage infection protein is inactivated. The nisin-producing Lactococcus lactis can be used in starter culture for manufacturing food products or other industrial applications.