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公开(公告)号：US20090050213A1
公开(公告)日：2009-02-26
申请号：US11918107
申请日：2006-04-28
CPC分类号： A61M39/1011 , A61M39/14 , A61M39/18 , A61M2039/1027 , F16L37/26 , F16L2201/44 , Y10T137/0402
摘要： The invention relates to a connector (10) comprising: a fluid leadthrough (20); a contact device (14); an essentially planar contact surface (16), and; a fluid leadthrough opening (18), which is designed for leading fluid though, the fluid leadthrough opening (18) passing through the contact surface (16); a sterile covering (64) designed for sterilely covering, at least in part, the contact surface (16) and/or an end of the fluid leadthrough opening (20) facing the contact surface, and; a coupling device (22), which is designed for engaging with a complementary coupling device (34) of a complementary connector (12) along a coupling direction, the coupling device (40) being essentially parallel to the contact surface (16). The invention also relates to relates to a connector system, to a use of a connector (10) and to a complementary connector (12) for connecting a fluid supply of the connector (10) to a fluid discharge in a sterile manner.
摘要翻译： 本发明涉及一种连接器（10），包括：流体引线（20）; 接触装置（14）; 基本上平面的接触表面（16），和 流体通过开口（18），其被设计用于引导流体通过所述流体穿通开口（18），所述流体穿通开口穿过所述接触表面（16）; 至少部分地无菌地覆盖面向接触表面的接触表面（16）和/或流体引导开口（20）的端部的无菌覆盖物（64），以及; 联接装置（22），其被设计用于沿着联接方向与互补连接器（12）的互补联接装置（34）接合，所述联接装置（40）基本上平行于所述接触表面（16）。 本发明还涉及连接器系统，使用连接器（10）和用于以无菌方式将连接器（10）的流体供应件连接到流体排放口的互补连接器（12）。
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公开(公告)号：US09295825B2
公开(公告)日：2016-03-29
申请号：US11918107
申请日：2006-04-28
CPC分类号： A61M39/1011 , A61M39/14 , A61M39/18 , A61M2039/1027 , F16L37/26 , F16L2201/44 , Y10T137/0402
摘要： A connector assembly has a connector (10) with a fluid leadthrough (20) and a contact device (14). The contact device has an essentially planar contact surface (16) and a fluid leadthrough opening (18) passing through the contact surface (16). A sterile covering (64) sterilely covers at least part of the contact surface (16) and/or an end of the fluid leadthrough opening (20) adjacent the contact surface (16). A coupling device (22) is provided in proximity to the contact surface (16) outwardly from the fluid leadthrough opening (18). The connector assembly further includes a complementary connector (12) with a complementary coupling device (34) that can engage with the coupling device (22) along a coupling direction (40) that is essentially parallel to the contact surface (16).
摘要翻译： 连接器组件具有带有流体引线（20）和接触装置（14）的连接器（10）。 接触装置具有基本平坦的接触表面（16）和穿过接触表面（16）的流体穿通开口（18）。 无菌覆盖物（64）无菌地覆盖邻近接触表面（16）的接触表面（16）和/或流体引导开口（20）的至少一部分。 联接装置（22）从流体引导开口（18）向外靠近接触表面（16）设置。 连接器组件还包括具有互补联接装置（34）的互补连接器（12），所述互补连接装置可沿着基本上平行于接触表面（16）的联接方向（40）与联接装置（22）接合。
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公开(公告)号：US09174181B2
公开(公告)日：2015-11-03
申请号：US12086318
申请日：2006-12-20
CPC分类号： B01F13/0022 , B01F11/0094 , B01F13/002 , B01F15/00902 , B01L3/5082 , B01L2300/0858 , C12M23/08 , C12M23/28 , C12M27/20
摘要： Disposable bioreactor for culturing cells in a nutrient medium, consisting of a reagent container which is sealable with a lid and which is capable of being subjected to a shaking process in a shaking device, where the reagent container is equipped with at least one web adjacent to the internal wall of the container, the web being arranged running vertically from the bottom upward, preferably in the shape of a helix.
摘要翻译： 用于在营养培养基中培养细胞的一次性生物反应器，其由可与盖子密封并且能够在摇动装置中进行摇动处理的试剂容器组成，其中试剂容器配备有至少一个与邻近 容器的内壁，腹板从底部向上垂直地布置，优选为螺旋形。
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公开(公告)号：US20090311775A1
公开(公告)日：2009-12-17
申请号：US12086318
申请日：2006-12-20
IPC分类号： C12M3/00
CPC分类号： B01F13/0022 , B01F11/0094 , B01F13/002 , B01F15/00902 , B01L3/5082 , B01L2300/0858 , C12M23/08 , C12M23/28 , C12M27/20
摘要： Disposable bioreactor for culturing cells in a nutrient medium, consisting of a reagent container which is sealable with a lid and which is capable of being subjected to a shaking process in a shaking device, where the reagent container is equipped with at least one web adjacent to the internal wall of the container, the web being arranged running vertically from the bottom upward, preferably in the shape of a helix.
摘要翻译： 用于在营养培养基中培养细胞的一次性生物反应器，其由可与盖子密封并且能够在摇动装置中进行摇动处理的试剂容器组成，其中试剂容器配备有至少一个与邻近 容器的内壁，腹板从底部向上垂直地布置，优选为螺旋形。
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5.发明授权Filtration cell for tangential flow filtration and filtration system making use of such cell 有权用于切向流过滤和过滤系统的过滤池利用这种电池公开(公告)号：US06312591B1
公开(公告)日：2001-11-06
申请号：US09150790
申请日：1998-09-10
IPC分类号： B01D6120
CPC分类号： B01D65/08 , B01D61/18 , B01D61/20 , B01D61/22 , B01D63/08 , B01D63/082 , B01D63/087 , B01D2313/086 , B01D2321/2016 , B01D2321/2083 , G01N2001/4016
摘要： A filtration cell for carrying out a tangential flow filtration of a sample liquid contains at least two blocks and at least two filtration elements arranged between each pair of two adjacent blocks. The filtration elements each include an outlet for filtrate, a sheet of support material and two generally flat ultrafiltration or microfiltration membranes, arranged on either side of the support material in a sandwich construction. Each of the blocks, at a side adjacent the membranes, is provided with a respective channel for feeding a flow of sample liquid tangentially over the membranes such that each channel is connected in parallel with the inlet for the flow of sample liquid to be filtered and with an outlet for a concentrated solution. Each channel includes in its longitudinal direction a number of subsequent channel sections separated by transitional zones and is constructed and arranged such that the main flow direction in subsequent sections changes abruptly in the transitional zones.
摘要翻译： 用于进行样品液体的切向流过滤的过滤池包含至少两个块和至少两个布置在每对相邻块之间的过滤元件。 过滤元件各自包括用于滤液的出口，一片支撑材料和两个大致平坦的超滤或微滤膜，其布置在夹层结构中的支撑材料的两侧。 每个块在邻近膜的一侧上设置有相应的通道，用于在膜上切向地供给样品液体流，使得每个通道与待进行过滤的样品液体流的入口平行地连接， 配有浓缩溶液出口。 每个通道在其纵向方向上包括多个由过渡区隔开的后续通道部分，并且构造和布置成使得后续部分中的主流动方向在过渡区域中突然变化。
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公开(公告)号：US20130313184A1
公开(公告)日：2013-11-28
申请号：US13979971
申请日：2011-12-27
申请人： Christopher Biddell
发明人： Christopher Biddell
IPC分类号： B01D35/30
CPC分类号： B01D35/30 , B01L3/5021 , B01L2300/0681 , G01N2001/4088
摘要： A filtration container for concentration of macromolecules is insertable into a filtrate recovery tube (5) and has an upper portion (2), a central portion (3) axially adjoining the upper portion (2), and a lower portion (4) axially adjoining the central portion (3). The upper portion (3) forms a hollow-cylindrical sample container (7) with an inlet opening (9) on its upper end face (8). The downwardly tapering central portion (3) has a filtration chamber (11) with two mutually opposed main walls (12, 13) running down toward one another. At least one of the main walls (12, 13) has a filter window (16) for receiving a planar membrane filter (17). The lower portion (4) forms a retentate chamber (21) adjoining the lower edge (18) of the filter window (16) A base (26) of the retentate chamber (21) slopes down on one side laterally.
摘要翻译： 用于浓缩大分子的过滤容器可插入滤液回收管（5）中，并且具有上部（2），轴向邻接上部（2）的中心部分（3）和与轴向相邻的下部分（4） 中心部分（3）。 上部（3）在其上端面（8）上形成具有入口（9）的中空圆柱形样品容器（7）。 向下渐缩的中心部分（3）具有过滤室（11），其中两个彼此相对的主壁（12,13）朝向彼此向下延伸。 至少一个主壁（12,13）具有用于接纳平面膜过滤器（17）的过滤窗（16）。 下部（4）形成邻接过滤窗（16）的下边缘（18）的滞留室（21）。滞留室（21）的基部（26）在一侧侧向倾斜。
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公开(公告)号：US09409109B2
公开(公告)日：2016-08-09
申请号：US13979971
申请日：2011-12-27
申请人： Christopher Biddell
发明人： Christopher Biddell
CPC分类号： B01D35/30 , B01L3/5021 , B01L2300/0681 , G01N2001/4088
摘要： A filtration container for concentration of macromolecules is insertable into a filtrate recovery tube (5) and has an upper portion (2), a central portion (3) axially adjoining the upper portion (2), and a lower portion (4) axially adjoining the central portion (3). The upper portion (3) forms a hollow-cylindrical sample container (7) with an inlet opening (9) on its upper end face (8). The downwardly tapering central portion (3) has a filtration chamber (11) with two mutually opposed main walls (12, 13) running down toward one another. At least one of the main walls (12, 13) has a filter window (16) for receiving a planar membrane filter (17). The lower portion (4) forms a retentate chamber (21) adjoining the lower edge (18) of the filter window (16) A base (26) of the retentate chamber (21) slopes down on one side laterally.
摘要翻译： 用于浓缩大分子的过滤容器可插入滤液回收管（5）中并具有上部（2），与上部（2）轴向相邻的中心部分（3）和与轴向相邻的下部分（4） 中心部分（3）。 上部（3）在其上端面（8）上形成具有入口（9）的中空圆柱形样品容器（7）。 向下渐缩的中心部分（3）具有过滤室（11），其中两个彼此相对的主壁（12,13）朝向彼此向下延伸。 至少一个主壁（12,13）具有用于接纳平面膜过滤器（17）的过滤窗（16）。 下部（4）形成邻接过滤窗（16）的下边缘（18）的滞留室（21）。滞留室（21）的基部（26）在一侧侧向倾斜。
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