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公开(公告)号：US5990176A
公开(公告)日：1999-11-23
申请号：US789679
申请日：1997-01-27
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： A61J1/00 , A61J3/00 , A61K9/08 , A61K31/08 , A61K47/02 , A61K47/04 , A61K47/10 , A61K47/12 , A61K47/14 , A61P23/00 , C07C63/04 , C09K3/00 , C07C43/12
CPC分类号： A61K47/02 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , A61K9/0019 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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2.发明授权Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid 有权氟醚组合物和在路易斯酸存在下抑制其降解的方法公开(公告)号：US06288127B1
公开(公告)日：2001-09-11
申请号：US09447853
申请日：1999-11-23
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： A61K3108
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
摘要翻译： 本发明涉及含有氟醚化合物和生理上可接受的路易斯酸抑制剂的麻醉组合物。 该组合物表现出改进的稳定性，并且在路易斯酸存在下不容易降解。
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公开(公告)号：US06444859B1
公开(公告)日：2002-09-03
申请号：US09924573
申请日：2001-08-08
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： C07C4312
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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4.发明授权Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid 有权氟醚组合物和在路易斯酸存在下抑制其降解的方法公开(公告)号：US06677492B2
公开(公告)日：2004-01-13
申请号：US10190271
申请日：2002-07-03
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorats A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorats A. Stelmach
IPC分类号： C07C4312
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
摘要翻译： 本发明涉及含有氟醚化合物和生理上可接受的路易斯酸抑制剂的麻醉组合物。 该组合物表现出改进的稳定性，并且在路易斯酸存在下不容易降解。
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5.发明申请公开(公告)号：US20060148906A1
公开(公告)日：2006-07-06
申请号：US11362954
申请日：2006-02-27
申请人： Christopher Bieniarz , Steve Chang , Keith Cromack , Shuyen Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl Speicher , Honorata Stelmach
发明人： Christopher Bieniarz , Steve Chang , Keith Cromack , Shuyen Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl Speicher , Honorata Stelmach
IPC分类号： A61K31/08
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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6.发明授权Method of purifying fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether 失效氟甲基-1,1,1,3,3,3-六氟异丙醚的纯化方法
公开(公告)号：US5763684A
公开(公告)日：1998-06-09
申请号：US913507
申请日：1997-09-16
CPC分类号： C07C41/36
摘要： The present invention relates to a method of removing bisfluoromethyl ether contained in fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether in a simple, effective manner, and is characterized in that fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether containing bisfluoromethyl ether is brought into contact with zeolite.
摘要翻译： PCT No.PCT / JP97 / 00128 Sec。 371日期：1997年9月16日 102（e）1997年9月16日PCT PCT 1997年1月22日PCT公布。 出版物WO97 / 27165 日期1997年7月31日本发明涉及以简单，有效的方式除去氟甲基-1,1,1,3,3,3-六氟异丙醚中所含的双氟甲基醚的方法，其特征在于氟甲基-1， 使含有双氟甲基醚的1,1,3,3,3-六氟异丙基醚与沸石接触。
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