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1.发明授权Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid 有权氟醚组合物和在路易斯酸存在下抑制其降解的方法公开(公告)号：US06677492B2
公开(公告)日：2004-01-13
申请号：US10190271
申请日：2002-07-03
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorats A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorats A. Stelmach
IPC分类号： C07C4312
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
摘要翻译： 本发明涉及含有氟醚化合物和生理上可接受的路易斯酸抑制剂的麻醉组合物。 该组合物表现出改进的稳定性，并且在路易斯酸存在下不容易降解。
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公开(公告)号：US5990176A
公开(公告)日：1999-11-23
申请号：US789679
申请日：1997-01-27
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： A61J1/00 , A61J3/00 , A61K9/08 , A61K31/08 , A61K47/02 , A61K47/04 , A61K47/10 , A61K47/12 , A61K47/14 , A61P23/00 , C07C63/04 , C09K3/00 , C07C43/12
CPC分类号： A61K47/02 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , A61K9/0019 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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3.发明授权Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid 有权氟醚组合物和在路易斯酸存在下抑制其降解的方法公开(公告)号：US06288127B1
公开(公告)日：2001-09-11
申请号：US09447853
申请日：1999-11-23
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： A61K3108
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
摘要翻译： 本发明涉及含有氟醚化合物和生理上可接受的路易斯酸抑制剂的麻醉组合物。 该组合物表现出改进的稳定性，并且在路易斯酸存在下不容易降解。
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公开(公告)号：US06444859B1
公开(公告)日：2002-09-03
申请号：US09924573
申请日：2001-08-08
申请人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
发明人： Christopher Bieniarz , Steve H. Chang , Keith R. Cromack , Shuyen L. Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl R. Speicher , Honorate A. Stelmach
IPC分类号： C07C4312
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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5.发明申请公开(公告)号：US20060148906A1
公开(公告)日：2006-07-06
申请号：US11362954
申请日：2006-02-27
申请人： Christopher Bieniarz , Steve Chang , Keith Cromack , Shuyen Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl Speicher , Honorata Stelmach
发明人： Christopher Bieniarz , Steve Chang , Keith Cromack , Shuyen Huang , Toshikazu Kawai , Manami Kobayashi , David Loffredo , Rajagopalan Raghavan , Earl Speicher , Honorata Stelmach
IPC分类号： A61K31/08
CPC分类号： A61K47/02 , A61K9/0019 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/14 , Y10S514/816
摘要： The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
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公开(公告)号：US6162443A
公开(公告)日：2000-12-19
申请号：US205460
申请日：1998-12-04
申请人： Mary Jane Flament-Garcia , Keith R. Cromack , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Earl R. Speicher
发明人： Mary Jane Flament-Garcia , Keith R. Cromack , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Earl R. Speicher
CPC分类号： B65D1/0207 , A61J1/00
摘要： A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
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公开(公告)号：US06558679B2
公开(公告)日：2003-05-06
申请号：US09740463
申请日：2000-12-19
申请人： Mary Jane Flament-Garcia , Keith R. Cromack , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Earl R. Speicher
发明人： Mary Jane Flament-Garcia , Keith R. Cromack , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Earl R. Speicher
IPC分类号： A61K700
CPC分类号： B65D1/0207 , A61J1/00
摘要： A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
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公开(公告)号：US6074668A
公开(公告)日：2000-06-13
申请号：US4876
申请日：1998-01-09
申请人： Mary Jane Flament-Garcia , Steve H. Chang , Keith R. Cromack , Joan Garapolo , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Patrick Rice , Jeffrey Setesak
发明人： Mary Jane Flament-Garcia , Steve H. Chang , Keith R. Cromack , Joan Garapolo , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Patrick Rice , Jeffrey Setesak
CPC分类号： A61J1/00 , B65D1/0207
摘要： A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polyethylene napthalate. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
摘要翻译： 药品。 药品包括由含有聚萘二甲酸乙二醇酯的材料构成的容器。 容器定义了一个内部空间。 含氟醚吸入麻醉剂的体积被容纳在由容器限定的内部空间中。
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公开(公告)号：US6083514A
公开(公告)日：2000-07-04
申请号：US4792
申请日：1998-01-09
申请人： Steve H. Chang , Keith R. Cromack , Mary Jane Flament-Garcia , Joan Garapolo , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Patrick Rice , Jeffrey Setesak
发明人： Steve H. Chang , Keith R. Cromack , Mary Jane Flament-Garcia , Joan Garapolo , David Loffredo , Rajagopalan Raghavan , George M. Ramsay , Patrick Rice , Jeffrey Setesak
CPC分类号： A61J1/00 , B65D1/0207
摘要： A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polymethylpentene. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
摘要翻译： 药品。 该药品包括由含有聚甲基戊烯的材料构成的容器。 容器定义了一个内部空间。 含氟醚吸入麻醉剂的体积被容纳在由容器限定的内部空间中。
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公开(公告)号：US5922754A
公开(公告)日：1999-07-13
申请号：US165930
申请日：1998-10-02
IPC分类号： C07D305/14 , A61K9/00 , A61K9/08 , A61K31/337 , A61K47/00 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61P35/00 , A61K31/335
CPC分类号： A61K9/0019 , A61K31/337 , A61K47/14 , A61K47/10 , A61K47/12
摘要： The present invention provides novel paclitaxel formulations which may be terminally sterilized and show long term stability in water containing admixtures.
摘要翻译： 本发明提供了新型紫杉醇制剂，其可以终末灭菌并在含水混合物中表现出长期的稳定性。
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