公开(公告)号：US20070238774A1

公开(公告)日：2007-10-11

申请号：US11767573

申请日：2007-06-25

申请人： Christopher BROOK ,  Wei Chen ,  Philip Dell'orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

发明人： Christopher BROOK ,  Wei Chen ,  Philip Dell'orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

IPC分类号： A61K31/403 ,  A61P9/04 ,  A61P9/10 ,  A61P9/12 ,  C07D209/82

CPC分类号： C07D209/88

摘要： The present invention relates to carvedilol phosphate salts, which include novel crystalline forms of carvedilol dihydrogen phosphate (i.e., dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy) ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.), and/or solvates thereof, compositions containing the aforementioned salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.

公开(公告)号：US20050240027A1

公开(公告)日：2005-10-27

申请号：US10518654

申请日：2003-06-27

申请人： Christopher Brook ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

发明人： Christopher Brook ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

IPC分类号： A61K31/403 ,  A61P9/00 ,  A61P9/04 ,  A61P9/12 ,  C07D209/82 ,  C07D209/88

CPC分类号： C07D209/88

摘要： The present invention relates to carvedilol phosphate salts, which include novel crystalline forms of carvedilol dihydrogen phosphate (i.e., dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.), and/or solvates thereof, compositions containing the aforementioned salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.

摘要翻译： 本发明涉及卡维地洛磷酸盐，其包括新颖的卡维地洛磷酸二氢盐的结晶形式（即，1-（咔唑-4-基氧基-3 - [[2-（邻甲氧基苯氧基）乙基]氨基] - 2-丙醇）和/或卡维地洛磷酸氢盐等）和/或其溶剂合物，含有上述盐和/或溶剂合物的组合物，以及使用上述盐和/或溶剂合物治疗高血压，充血性心力衰竭和 心绞痛等

公开(公告)号：US20070259940A1

公开(公告)日：2007-11-08

申请号：US11767566

申请日：2007-06-25

申请人： Christopher BROOK ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

发明人： Christopher BROOK ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

IPC分类号： A61K31/403 ,  A61P9/04 ,  C07D209/82

CPC分类号： C07D209/88

摘要： The present invention relates to carvedilol phosphate salts, which include novel crystalline forms of carvedilol dihydrogen phosphate (i.e., dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy) ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate,etc.), and/or solvates thereof, compositions containing the aforementioned salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.

摘要翻译： 本发明涉及卡维地洛磷酸盐，其包括新颖的卡维地洛磷酸二氢盐的结晶形式（即，1-（咔唑-4-基氧基-3 - [[2-（邻甲氧基苯氧基）乙基]氨基] - 2-丙醇）和/或卡维地洛磷酸氢盐等）和/或其溶剂合物，含有上述盐和/或溶剂合物的组合物，以及使用上述盐和/或溶剂化物治疗高血压，充血性心力衰竭和 心绞痛等

公开(公告)号：US20070244182A1

公开(公告)日：2007-10-18

申请号：US11767586

申请日：2007-06-25

申请人： Christopher BROOK ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

发明人： Christopher BROOK ,  Wei Chen ,  Philip Dell'Orco ,  Lee Katrincic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

IPC分类号： A61K31/403 ,  C07D209/82

CPC分类号： C07D209/88

摘要： The present invention relates to carvedilol phosphate salts, which include novel crystalline forms of carvedilol dihydrogen phosphate (i.e., dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy) ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.), and/or solvates thereof, compositions containing the aforementioned salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.

公开(公告)号：US20070244181A1

公开(公告)日：2007-10-18

申请号：US11767581

申请日：2007-06-25

申请人： Christopher BROOK ,  Wei Chen ,  Philip Dell'orco ,  Lee Katrinic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

发明人： Christopher BROOK ,  Wei Chen ,  Philip Dell'orco ,  Lee Katrinic ,  Ann Louvet ,  Choon Oh ,  Paul Spoors ,  Christopher Werner

IPC分类号： A61K31/403 ,  A61P9/04 ,  A61P9/10 ,  A61P9/12 ,  C07D209/82

CPC分类号： C07D209/88

摘要： The present invention relates to carvedilol phosphate salts, which include novel crystalline forms of carvedilol dihydrogen phosphate (i.e., dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy) ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.), and/or solvates thereof, compositions containing the aforementioned salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.

摘要翻译： 本发明涉及卡维地洛磷酸盐，其包括新颖的卡维地洛磷酸二氢盐的结晶形式（即，1-（咔唑-4-基氧基-3 - [[2-（邻甲氧基苯氧基）乙基]氨基] - 2-丙醇）和/或卡维地洛磷酸氢盐等）和/或其溶剂合物，含有上述盐和/或溶剂合物的组合物，以及使用上述盐和/或溶剂合物治疗高血压，充血性心力衰竭和 心绞痛等