公开(公告)号：US09946834B2

公开(公告)日：2018-04-17

申请号：US13395857

申请日：2010-09-21

申请人： Christopher Johnson ,  Marina Tarunina ,  Yen Choo ,  Simon Lister ,  Robert Merrifield

发明人： Christopher Johnson ,  Marina Tarunina ,  Yen Choo ,  Simon Lister ,  Robert Merrifield

IPC分类号： G01N33/48 ,  G06F19/24

CPC分类号： G06F19/24

摘要： One embodiment of the invention provides a method of processing cell culture data. The data comprises results from a large number of samples, the results being obtained by performing multiple stages of cell culture in succession on each sample. Each stage represents a cell culture treatment having a particular set of conditions, such that each sample follows a protocol specified by the identity and order of the treatments applied to the cell culture. The method includes specifying a subset of the samples that yielded a desired cell culture outcome. The method further includes performing a computer-implemented analysis of the results from the samples in the subset to produce an ordering or grouping for the results. The ordering or grouping helps to identify one or more protocols that are effective for obtaining the desired cell culture outcome. The analysis for producing the ordering or grouping utilizes information on similarities between different protocols.

公开(公告)号：US20120208227A1

公开(公告)日：2012-08-16

申请号：US13395857

申请日：2010-09-21

申请人： Christopher Johnson ,  Marina Tarunina ,  Yen Choo ,  Simon Lister ,  Robert Merrifield

发明人： Christopher Johnson ,  Marina Tarunina ,  Yen Choo ,  Simon Lister ,  Robert Merrifield

IPC分类号： G06F19/00 ,  C12M1/34 ,  G01N21/17

CPC分类号： G06F19/24

摘要： One embodiment of the invention provides a method of processing cell culture data. The data comprises results from a large number of samples, the results being obtained by performing multiple stages of cell culture in succession on each sample. Each stage represents a cell culture treatment having a particular set of conditions, such that each sample follows a protocol specified by the identity and order of the treatments applied to the cell culture. The method includes specifying a subset of the samples that yielded a desired cell culture outcome. The method further includes performing a computer-implemented analysis of the results from the samples in the subset to produce an ordering or grouping for the results. The ordering or grouping helps to identify one or more protocols that are effective for obtaining the desired cell culture outcome. The analysis for producing the ordering or grouping utilises information on similarities between different protocols.

摘要翻译： 本发明的一个实施方案提供了处理细胞培养数据的方法。 数据包括大量样品的结果，结果是通过在每个样品上连续进行多个细胞培养阶段获得的。 每个阶段表示具有特定条件集合的细胞培养处理，使得每个样品遵循由应用于细胞培养物的处理的身份和顺序指定的方案。 该方法包括指定产生所需细胞培养结果的样品的子集。 该方法还包括对来自子集中的样本的结果进行计算机实现的分析，以产生用于结果的排序或分组。 排序或分组有助于识别对于获得所需细胞培养结果有效的一种或多种方案。 生产排序或分组的分析利用不同协议之间相似性的信息。