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公开(公告)号：US09598477B2
公开(公告)日：2017-03-21
申请号：US14421903
申请日：2013-08-09
发明人： Hitoshi Yamashita , Tatsuya Kusudo
CPC分类号： C07K14/4703 , A23L29/281 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K38/00 , A61K48/00 , A61K48/005 , C07K14/00 , C12N5/0653 , C12N15/113 , C12N2310/14 , C12N2501/998 , C12N2510/00 , G01N33/5023 , G01N33/6872 , G01N2500/04 , G01N2500/10 , G01N2800/04
摘要： The present invention addresses the problem of providing a means which is effective for the induction of the differentiation of a brown adipocyte and therefore enables a brown adipocyte to be used for and applied to, for example, the prevention/treatment of obesity or metabolic syndrome. Provided is a brown adipocyte differentiation-inducing agent containing, as an active ingredient, (1) CREG1 protein or (2) an expression vector carrying CREG1 gene.
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公开(公告)号：US20150232522A1
公开(公告)日：2015-08-20
申请号：US14421903
申请日：2013-08-09
发明人： Hitoshi Yamashita , Tatsuya Kusudo
CPC分类号： C07K14/4703 , A23L29/281 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K38/00 , A61K48/00 , A61K48/005 , C07K14/00 , C12N5/0653 , C12N15/113 , C12N2310/14 , C12N2501/998 , C12N2510/00 , G01N33/5023 , G01N33/6872 , G01N2500/04 , G01N2500/10 , G01N2800/04
摘要： The present invention addresses the problem of providing a means which is effective for the induction of the differentiation of a brown adipocyte and therefore enables a brown adipocyte to be used for and applied to, for example, the prevention/treatment of obesity or metabolic syndrome. Provided is a brown adipocyte differentiation-inducing agent containing, as an active ingredient, (1) CREG1 protein or (2) an expression vector carrying CREG1 gene.
摘要翻译： 本发明解决了提供一种对诱导褐色脂肪细胞分化有效的手段的问题，因此能使棕色脂肪细胞用于例如预防/治疗肥胖或代谢综合征。 提供含有作为活性成分的（1）CREG1蛋白或（2）携带CREG1基因的表达载体的棕色脂肪细胞分化诱导剂。
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