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1.发明授权Nucleic acids encoding dog gastric lipase and their use for the production of polypeptides 失效编码狗胃脂肪酶的核酸及其用于产生多肽的用途
公开(公告)号：US5807726A
公开(公告)日：1998-09-15
申请号：US227108
申请日：1994-04-13
IPC分类号： C12N15/09 , A61K38/00 , A61K38/46 , A61P3/06 , C07H21/04 , C12N1/21 , C12N9/20 , C12N15/55 , C12N15/63
摘要： The present invention relates to dog gastric lipase as obtained by genetic engineering as well as to the nucleotide sequence encoding this recombinant DGL. It also relates to the use of this recombinant DGL for the production of pharmaceutical compositions intended especially for the treatment of pathologies linked to the insufficiency, or even the absence, of secretion of lipases in the body of an individual.
摘要翻译： 本发明涉及通过遗传工程获得的狗胃脂肪酶以及编码该重组DGL的核苷酸序列。 它还涉及这种重组DGL用于制备药物组合物的用途，该药物组合物特别用于治疗与个体身体中脂肪酶分泌不足或甚至不存在相关的病理学。
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2.发明授权Polypeptide derivatives of dog gastric lipase and pharmaceutical compositions containing same 失效狗胃脂肪酶的多肽衍生物和含有其的药物组合物
公开(公告)号：US05998189A
公开(公告)日：1999-12-07
申请号：US73674
申请日：1998-05-06
摘要： The present invention relates to polypeptide derivatives of dog gastric lipase as obtained by genetic engineering as well as to the nucleotide sequence encoding this recombinant DGL. It also relates to the use of this recombinant DGL for the production of pharmaceutical compositions intended especially for the treatment of pathologies linked to the insufficiency, or even the absence, of secretion of lipases in the body of an individual.
摘要翻译： 本发明涉及通过遗传工程获得的狗胃脂肪酶的多肽衍生物以及编码该重组DGL的核苷酸序列。 它还涉及这种重组DGL用于制备药物组合物的用途，该药物组合物特别用于治疗与个体身体中脂肪酶分泌不足或甚至不存在相关的病理学。
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