公开(公告)号：US6150538A

公开(公告)日：2000-11-21

申请号：US250645

申请日：1999-02-16

Applicant: Claude Delphis

Inventor： Claude Delphis

IPC: C07D317/34 ,  A61K8/49 ,  A61K8/96 ,  A61Q5/02 ,  A61Q13/00 ,  C07D303/40 ,  C07D313/00 ,  C07D315/00 ,  C11B9/00 ,  C11D3/50

CPC classification number: C07D315/00

Abstract: Manufacture of a molecule which is of important olfactory interest for perfumers. This molecule belongs to the group of macrocyclic lactones with a musk odor. The manufacturing process consists in preparing cis-16-hydroxy-9-hexadecenoic acid or an ester of this acid, which is a precursor of cis-isoambrettolide, the latter being obtained by macrolactonization in a very high degree of purity. Use as a fragrance material.

Abstract translation: 制造对香料有重要嗅觉兴趣的分子。 该分子属于具有麝香气味的大环内酯类。 制备方法包括制备顺式-16-羟基-9-十六碳烯酸或该酸的酯，该酸是顺式 - 异戊内酯的前体，后者是以非常高的纯度通过大环内酯化获得的。 用作香料。

公开(公告)号：US06225281B1

公开(公告)日：2001-05-01

申请号：US09572242

申请日：2000-05-17

Applicant: Claude Delphis

Inventor： Claude Delphis

IPC: A61K746

CPC classification number: C07D315/00

Abstract: Manufacture of a molecule which is of important olfactory interest for perfumers. This molecule belongs to the group of macrocyclic lactones with a musk odor. The manufacturing process consists in preparing cis-16-hydroxy-9-hexadecenoic acid or an ester of this acid, which is a precursor of cis-isoambrettolide, the latter being obtained by macrolactonization in a very high degree of purity. Use as a fragrance material.

Abstract translation: 制造对香料有重要嗅觉兴趣的分子。 该分子属于具有麝香气味的大环内酯类。 制备方法包括制备顺式-16-羟基-9-十六碳烯酸或该酸的酯，该酸是顺式 - 异戊内酯的前体，后者是以非常高的纯度通过大环内酯化获得的。 用作香料。

公开(公告)号：US06284900B1

公开(公告)日：2001-09-04

申请号：US09636405

申请日：2000-08-10

Applicant: Claude Delphis

Inventor： Claude Delphis

IPC: C07D31300

CPC classification number: C07D313/00

Abstract: The invention relates to a molecule which is of important olfactory interest for perfumers. This molecule, i.e. the cis-isoambrettoide, which has a high degree of isomer purity belongs to the group of macrocyclic lactones with a musk odor. The invention also relates to its use as a fragrance.

Abstract translation: 本发明涉及一种对香料具有重要的嗅觉兴趣的分子。具有高度异构体纯度的该分子即顺式 - 异丁酰苯胺属于具有麝香气味的大环内酯类。本发明还涉及其 用作香水。