Implant of low radial strength
    3.
    发明申请
    Implant of low radial strength 有权
    植入物径向强度低

    公开(公告)号:US20060064160A1

    公开(公告)日:2006-03-23

    申请号:US11222595

    申请日:2005-09-09

    IPC分类号: A61F2/06

    摘要: The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.

    摘要翻译: 本发明涉及一种包括可生物降解材料的血管内植入物,并且具有管状主体,该管状主体在端部处是开口的,并且可从未膨胀状态扩张到膨胀状态。 植入物的设计使得当处于膨胀状态的植入物经受5至30kPa(0.05-0.3巴)范围内的径向作用压缩压力时,植入物的横截面面积减小至70%或 较小的原始横截面积或植入物的内部体积减少到原始内部体积的70%或更小。

    Endoprosthesis comprising a magnesium alloy
    6.
    发明申请
    Endoprosthesis comprising a magnesium alloy 审中-公开
    包含镁合金的内假体

    公开(公告)号:US20060052864A1

    公开(公告)日:2006-03-09

    申请号:US11221344

    申请日:2005-09-07

    IPC分类号: A61F2/06

    CPC分类号: A61L31/148 A61L31/022

    摘要: An endoprosthesis, in particular an intraluminal endoprosthesis such as a stent, comprises a carrier structure, which includes at least one component comprising a magnesium alloy of the following composition: Rare earth metals: between about 2.0 and about 5.0% by weight, with neodymium between about 1.5 and about 3.0% by weight Yttrium: between about 3.5% and about 4.5% by weight Zirconium: between about 0.3% and about 1.0% by weight Balance: between 0 and about 0.5% by weight wherein magnesium occupies the proportion by weight that remains to 100% by weight in the alloy.

    摘要翻译: 内置假体,特别是管腔内假体,例如支架,包括载体结构,其包括至少一种包含以下组成的镁合金的组分:稀土金属:约2.0至约5.0重量%之间,钕在 约1.5重量%至约3.0重量%钇:约3.5重量%至约4.5重量%锆:约0.3重量%至约1.0重量%平均:0至约0.5重量%其中镁占重量的比例, 在合金中保持为100重量%。

    Stent comprising a coating system
    10.
    发明申请
    Stent comprising a coating system 审中-公开
    支架包括涂层系统

    公开(公告)号:US20060241742A1

    公开(公告)日:2006-10-26

    申请号:US10562376

    申请日:2004-06-14

    IPC分类号: A61F2/82

    摘要: A stent comprises a tubular base body which is open on the front sides thereof and has a peripheral wall that is at least partially covered with a coating system consisting of at least one polymer carrier and at least one pharmacologically active substance, which is released into the surrounding tissue once the stent has been implanted in the human or animal body. The invention creates a coating system which enables an optimum local application of the active ingredient. A concentration of the substance, a morphological structure of the carrier(s), a material modification of the carrier(s), and/or a layer thickness of the carrier(s), are predetermined in the longitudinal direction of the stent, in such a way that the elution varies locally in the longitudinal direction of the stent and is determined according to the pathophysiological and/or rheological conditions to be expected during the application.

    摘要翻译: 支架包括在其前侧开口的管状基体,并且具有至少部分地覆盖有由至少一种聚合物载体和至少一种药理活性物质组成的涂层系统的周壁,其被释放到 一旦将支架植入人体或动物体内,就会围绕组织。 本发明产生一种涂覆系统,其能够最佳地局部施用活性成分。 物质的浓度,载体的形态结构,载体的材料改性和/或载体的层厚度在支架的纵向上是预定的,在 这样一种方式使得洗脱在支架的纵向上局部变化,并且根据在施用期间预期的病理生理学和/或流变学条件来确定。