利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

103 条记录 (耗时 0.02 秒)

    Endoprosthesis comprising a magnesium alloy
    1.
    发明申请
    Endoprosthesis comprising a magnesium alloy 审中-公开
    包含镁合金的内假体

    公开(公告)号：US20060052864A1

    公开(公告)日：2006-03-09

    申请号：US11221344

    申请日：2005-09-07

    申请人： Claus Harder ,  Marc Kuttler ,  Bodo Gerold ,  Heinz Mueller

    发明人： Claus Harder ,  Marc Kuttler ,  Bodo Gerold ,  Heinz Mueller

    IPC分类号： A61F2/06

    CPC分类号： A61L31/148 ,  A61L31/022

    摘要： An endoprosthesis, in particular an intraluminal endoprosthesis such as a stent, comprises a carrier structure, which includes at least one component comprising a magnesium alloy of the following composition: Rare earth metals: between about 2.0 and about 5.0% by weight, with neodymium between about 1.5 and about 3.0% by weight Yttrium: between about 3.5% and about 4.5% by weight Zirconium: between about 0.3% and about 1.0% by weight Balance: between 0 and about 0.5% by weight wherein magnesium occupies the proportion by weight that remains to 100% by weight in the alloy.

    摘要翻译： 内置假体，特别是管腔内假体，例如支架，包括载体结构，其包括至少一种包含以下组成的镁合金的组分：稀土金属：约2.0至约5.0重量％之间，钕在 约1.5重量％至约3.0重量％钇：约3.5重量％至约4.5重量％锆：约0.3重量％至约1.0重量％平均：0至约0.5重量％其中镁占重量的比例， 在合金中保持为100重量％。

    Implant of low radial strength
    5.
    发明申请
    Implant of low radial strength 有权
    植入物径向强度低

    公开(公告)号：US20060064160A1

    公开(公告)日：2006-03-23

    申请号：US11222595

    申请日：2005-09-09

    申请人： Bodo Gerold ,  Claus Harder ,  Bernd Heublein ,  Heinz Mueller ,  Eva Heublein ,  Nora Heublein ,  Christoph Heublein

    发明人： Bodo Gerold ,  Claus Harder ,  Bernd Heublein ,  Heinz Mueller ,  Eva Heublein ,  Nora Heublein ,  Christoph Heublein

    IPC分类号： A61F2/06

    CPC分类号： A61F2/86 ,  A61F2/90 ,  A61F2/91 ,  A61L31/022

    摘要： The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.

    摘要翻译： 本发明涉及一种包括可生物降解材料的血管内植入物，并且具有管状主体，该管状主体在端部处是开口的，并且可从未膨胀状态扩张到膨胀状态。 植入物的设计使得当处于膨胀状态的植入物经受5至30kPa（0.05-0.3巴）范围内的径向作用压缩压力时，植入物的横截面面积减小至70％或 较小的原始横截面积或植入物的内部体积减少到原始内部体积的70％或更小。

    CONTROL OF THE DEGRADATION OF BIODEGRADABLE IMPLANTS USING A COATING
    7.
    发明申请
    CONTROL OF THE DEGRADATION OF BIODEGRADABLE IMPLANTS USING A COATING 审中-公开
    使用涂层控制生物可降解植入物的降解

    公开(公告)号：US20090208555A1

    公开(公告)日：2009-08-20

    申请号：US10596791

    申请日：2004-09-07

    申请人： Marc Kuttler ,  Claus Harder ,  Carsten Momma ,  Heinz Mueller ,  Daniel Lootz

    发明人： Marc Kuttler ,  Claus Harder ,  Carsten Momma ,  Heinz Mueller ,  Daniel Lootz

    IPC分类号： A61K9/00 ,  A61P9/10

    CPC分类号： A61F2/82 ,  A61F2210/0004 ,  A61L31/10 ,  A61L31/148

    摘要： The invention relates to an endovascular implant, which is at least largely biodegradable and whose in vivo degradation can be controlled. To achieve this, the implant comprises a tubular base body, open on its end faces and consisting of at least one biodegradable material, said base body having an in vivo, location-dependent first degradation characteristic D1(x), in addition to a coating that covers the base body completely or in sections and consists of a biodegradable material, said coating having an in vivo, location-dependent second degradation characteristic D2(x). According to the invention, a location-dependent cumulative degradation characteristic D(x) in one location (x) is made up of the sum of the respective degradation characteristics D1(x) and D2(x) in said location (x) and the location-dependent cumulative degradation characteristic D(x) is predetermined by a variation of the second degradation characteristic D2(x) in such a way that the degradation in the given location (x) of the implant takes place over a predeterminable time period at a predeterminable degradation rate.

    摘要翻译： 本发明涉及一种血管内植入物，其至少在很大程度上是可生物降解的并且其体内降解可被控制。 为了实现这一点，植入物包括管状基体，其在其端面上开口并由至少一种生物可降解材料组成，所述基体除了涂层之外还具有体内位置依赖性的第一降解特性D1（x） 其完全或部分地覆盖基体，并且由可生物降解的材料组成，所述涂层具有体内位置相关的第二降解特征D2（x）。 根据本发明，一个位置（x）中的位置相关的累积退化特性D（x）由所述位置（x）中的各自的劣化特性D1（x）和D2（x）之和构成， 位置相关的累积退化特性D（x）是通过第二劣化特性D2（x）的变化来预定的，使得植入物的给定位置（x）的劣化发生在预定时间段 可预测的降解率。

    MAGNESIUM ALLOY AND THE RESPECTIVE MANUFACTURING METHOD
    10.
    发明申请
    MAGNESIUM ALLOY AND THE RESPECTIVE MANUFACTURING METHOD 有权
    镁合金及相关制造方法

    公开(公告)号：US20080031765A1

    公开(公告)日：2008-02-07

    申请号：US11829665

    申请日：2007-07-27

    申请人： Bodo Gerold ,  Heinz Mueller ,  Joerg Loeffler ,  Anja Haenzi ,  Peter Uggowitzer

    发明人： Bodo Gerold ,  Heinz Mueller ,  Joerg Loeffler ,  Anja Haenzi ,  Peter Uggowitzer

    IPC分类号： C22C23/00 ,  B22D27/09 ,  C22C23/04 ,  C22C23/06

    CPC分类号： C22C23/00 ,  A61L31/022 ,  A61L31/148 ,  C22C23/04

    摘要： A magnesium alloy, comprising: Y:0.5-10  Zn:0.5-6   Ca:0.05-1   Mn:  0-0.5 Ag:0-1 Ce:0-1 Zr:0-1 or Si: 0-0.4, wherein the amounts are based on weight-percent of the alloy and Mg, and manufacturing-related impurities constitute the remainder of the alloy to a total of 100 weight-percent. Also disclosed is a method for manufacturing such an alloy and a biodegradable implant formed therefrom.

    摘要翻译： 一种镁合金，包括：

    Y： ENTRY> 0.5-10 Zn： 0.5-6 ENTRY /> Ca： 0.05-1 Mn： 0-0.5 < ENTRY> Ag： 0-1 ENTRY> 0-1 Zr： 0-1或Si：0-0.4， / ROW> 其中的量基于合金和Mg的重量百分比，制造相关杂质构成 该合金总共达到100重量％。 还公开了一种用于制造这种合金和由其形成的可生物降解的植入物的方法。