公开(公告)号：US20200246643A1

公开(公告)日：2020-08-06

申请号：US16746148

申请日：2020-01-17

Applicant: Colgate-Palmolive Company

Inventor： Sandra PEREIRA RAMOS ,  Luiz Alberto GONCALVES FILHO ,  Fernanda CORREA ,  Tatiana CINQUETTI ,  Paulo FOCASSIO

IPC: A61Q11/00 ,  A61K8/44 ,  A61K8/34 ,  A61K8/81 ,  A61K8/368

Abstract: Disclosed herein are oral care compositions comprising: an orally acceptable vehicle comprising greater than about 50 wt. % water; and a preservative system comprising: benzyl alcohol, benzoic acid or a salt of benzoic acid; and an alkylene glycol. Methods of making and using these compositions are also described herein.

公开(公告)号：US20230355492A1

公开(公告)日：2023-11-09

申请号：US17632176

申请日：2021-11-09

Applicant: Colgate-Palmolive Company

Inventor： Sandra PEREIRA RAMOS ,  Fernanda CORREA ,  Tatiana CINQUETTI ,  Ariel HASKEL ,  Natalia CASTRO DE SOUZA ,  Jeffrey Merl MILLER

IPC: A61K8/41 ,  A61K8/34 ,  A61K8/21 ,  A61Q11/00

CPC classification number: A61K8/416 ,  A61K8/34 ,  A61K8/21 ,  A61Q11/00 ,  A61K2800/524

Abstract: This invention provides, amongst other things, a preservative system for aqueous oral care compositions that comprises the addition of one or more quaternary ammonium antimicrobial agents (e.g., cetylpyridinium chloride (CPC)) in combination with comprising benzyl alcohol in a preservative system, can surprisingly allow for the use of relatively less benzyl alcohol while still maintaining antimicrobial efficacy and not adversely affecting the flavor of the composition. The added benefit in using relatively less benzyl alcohol, in addition to lower cost and expense, is also that the flavor or the overall composition is less impacted.

公开(公告)号：US20200009030A1

公开(公告)日：2020-01-09

申请号：US16487224

申请日：2018-02-21

Applicant: Colgate-Palmolive Company

Inventor： Enzo UTIMA ,  Tatiana CINQUETTI ,  Fernanda CORREA ,  Paulo FOCASSIO ,  Debora PEDROSO

IPC: A61K8/19 ,  A61K8/34 ,  A61K8/365 ,  A61Q11/00

Abstract: Disclosed herein are improved oral care formulations comprising precipitated calcium carbonate (PCC) and preservative combinations selected from the group consisting of i) phenethyl alcohol and caprylyl glycol, and ii) benzyl alcohol and caprylyl glycol. Methods of making and using the compositions are also provided.