公开(公告)号：US20140314829A1

公开(公告)日：2014-10-23

申请号：US14366436

申请日：2012-12-18

Applicant: Colgate -Palmolive Company ,  E.I. DU PONT DE NEMOURS AND COMPANY

Inventor： Thomas J. Boyd ,  Guofeng Xu ,  Richard Adams ,  Robert Pierce ,  Steven Miller ,  David Viscio ,  Kari A. Fosser ,  Robert Dicosimo ,  Hong Wang

IPC: A61K8/66 ,  A61Q11/00 ,  A61K8/37 ,  A61K8/22

CPC classification number: A61K8/66 ,  A61K8/22 ,  A61K8/37 ,  A61K8/375 ,  A61K2800/87 ,  A61Q11/00

Abstract: Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided.

Abstract translation: 本文描述的是牙齿增白条，其包括具有连接到其上的颗粒漂白成分的可水合粘合剂膜，其中在水合时，颗粒漂白成分释放过氧化氢，其由具有过水解活性的酶催化剂使用以酶促产生有效量的过酸漂白剂 从酰基供体底物。 还提供了制造和使用牙齿美白条的方法。

公开(公告)号：US09884000B2

公开(公告)日：2018-02-06

申请号：US14366436

申请日：2012-12-18

Applicant: Colgate-Palmolive Company ,  E.I. DU PONT DE NEMOURS AND COMPANY

Inventor： Thomas J. Boyd ,  Guofeng Xu ,  Richard Adams ,  Robert Pierce ,  Steven Miller ,  David Viscio ,  Kari A. Fosser ,  Robert Dicosimo ,  Hong Wang

IPC: A61K8/66 ,  A61Q11/00 ,  A61K8/37 ,  A61K8/22

CPC classification number: A61K8/66 ,  A61K8/22 ,  A61K8/37 ,  A61K8/375 ,  A61K2800/87 ,  A61Q11/00

Abstract: Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided.

公开(公告)号：US20150265511A1

公开(公告)日：2015-09-24

申请号：US14364738

申请日：2012-12-18

Applicant: Colgate-Palmolive Company ,  E.I. DU PONT DE NEMOURS AND COMPANY

Inventor： Thomas Boyd ,  Guofeng Xu ,  Richard Adams ,  Robert Pierce ,  Derek Samaroo ,  David Viscio ,  Kari A. Fosser ,  Robert Dicosimo ,  Hong Wang

IPC: A61K8/38 ,  B65D81/32 ,  A61K8/66 ,  B65D35/22 ,  A61K8/04 ,  A61Q11/00

CPC classification number: A61K8/38 ,  A61K8/042 ,  A61K8/22 ,  A61K8/375 ,  A61K8/66 ,  A61K2800/87 ,  A61K2800/882 ,  A61Q11/00 ,  B65D35/22 ,  B65D81/3261

Abstract: Described herein are packages for storing and dispensing multi-part tooth whitening formulations, comprising a deformable material configured to form two or more sealed chambers, e.g., wherein the first chamber contains a low viscosity liquid solution comprising an enzyme having perhydrolytic activity, and the second chamber contains a peroxide source and a at least one acyl donor substrate. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided.

Abstract translation: 本文描述的是用于存储和分配多部分牙齿美白配方的包装，其包括构造成形成两个或更多个密封室的可变形材料，例如，其中第一室含有包含具有过水解活性的酶的低粘度液体溶液， 室含有过氧化物源和至少一个酰基供体底物。 还提供了使用该原理的特定的多部分牙齿美白配方及其使用方法。

公开(公告)号：US11033476B2

公开(公告)日：2021-06-15

申请号：US16566932

申请日：2019-09-11

Applicant: Colgate-Palmolive Company

Inventor： Jennifer Gronlund ,  Guofeng Xu ,  Venda Porter Maloney ,  Junhong Mao ,  Shaotang Yuan ,  Suman Chopra ,  Jodie Parker ,  Rajnish Kohli ,  Robert Dicosimo ,  Kari A. Fosser ,  Sharon L. Haynie ,  Mark S. Payne ,  John T. Gannon

IPC: A61K8/66 ,  A61K8/81 ,  A61K8/37 ,  A61K8/25 ,  A61Q11/00 ,  A61K8/22

Abstract: An oral care composition including an orally acceptable vehicle is disclosed. The orally acceptable vehicle includes a source of hydrogen peroxide, an acyl donor, and an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.

公开(公告)号：US10098824B2

公开(公告)日：2018-10-16

申请号：US14364738

申请日：2012-12-18

Applicant: Colgate-Palmolive Company ,  E.I. DU PONT DE NEMOURS AND COMPANY

Inventor： Thomas Boyd ,  Guofeng Xu ,  Richard Adams ,  Robert Pierce ,  Derek Samaroo ,  David Viscio ,  Kari A. Fosser ,  Robert Dicosimo ,  Hong Wang

IPC: A61K8/66 ,  A61K8/22 ,  A61K8/37 ,  A61C15/04 ,  C07H21/04 ,  A61K8/38 ,  A61Q11/00 ,  A61K8/04 ,  B65D35/22 ,  B65D81/32

Abstract: Described herein are packages for storing and dispensing multi-part tooth whitening formulations, comprising a deformable material configured to form two or more sealed chambers, e.g., wherein the first chamber contains a low viscosity liquid solution comprising an enzyme having perhydrolytic activity, and the second chamber contains a peroxide source and a at least one acyl donor substrate. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided.