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公开(公告)号：US20100297112A1
公开(公告)日：2010-11-25
申请号：US12064633
申请日：2006-08-25
申请人： Colin Green , Lloyd Kelland , Gail Rowlinson-Bruza
发明人： Colin Green , Lloyd Kelland , Gail Rowlinson-Bruza
IPC分类号： A61K39/395 , A61P35/00 , A61K31/352
CPC分类号： A61K31/337 , A61K31/352 , A61K39/395 , A61K2300/00
摘要： The present invention relates to combinations of compounds such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and vascular endothelial growth factor binders, in particular the monoclonal antibody Avastin™ (bevacizumab). More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical formulations containing such combinations.
摘要翻译： 本发明涉及化合物如呫吨酮乙酸类化合物如5,6-二甲基呫吨酮-4-乙酸（DMXAA）和血管内皮生长因子结合剂，特别是单克隆抗体Avastin TM（贝伐珠单抗））的组合。 更具体地说，本发明涉及这样的组合在治疗癌症中的用途以及含有这种组合的药物制剂。
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公开(公告)号：US20100104565A1
公开(公告)日：2010-04-29
申请号：US12064632
申请日：2006-08-25
IPC分类号： A61K39/395 , A61K31/352 , A61P35/00 , A61K31/517 , A61K31/5377
CPC分类号： A61K31/5377 , A61K31/352 , A61K31/517 , A61K39/395 , A61K39/39541 , A61K2300/00
摘要： The present invention relates to combinations of the xanthenone acetic acids class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and EGFR signalling pathway inhibitors. More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical compositions containing such combinations.
摘要翻译： 本发明涉及呫吨酮类乙酸类，例如5,6-二甲基呫吨酮-4-乙酸（DMXAA）和EGFR信号通路抑制剂的组合。 更具体地，本发明涉及这样的组合在治疗癌症中的用途以及含有这些组合的药物组合物。
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公开(公告)号：US20070072819A1
公开(公告)日：2007-03-29
申请号：US11512730
申请日：2006-08-29
申请人： David Becker , Colin Green
发明人： David Becker , Colin Green
CPC分类号： C07H21/04 , A61K31/711 , A61K38/00 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2320/32
摘要： A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.
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公开(公告)号：US20070078103A1
公开(公告)日：2007-04-05
申请号：US11510496
申请日：2006-08-25
申请人： David Becker , Colin Green
发明人： David Becker , Colin Green
IPC分类号： A61K48/00
CPC分类号： C07H21/04 , A61K31/711 , A61K38/00 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2320/32
摘要： A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.
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公开(公告)号：US20070060538A1
公开(公告)日：2007-03-15
申请号：US11510280
申请日：2006-08-25
申请人： David Becker , Colin Green
发明人： David Becker , Colin Green
IPC分类号： A61K48/00
CPC分类号： C07H21/04 , A61K31/711 , A61K38/00 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2320/32
摘要： A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.
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公开(公告)号：US08167533B2
公开(公告)日：2012-05-01
申请号：US12771898
申请日：2010-04-30
申请人： Dan Lucy , Michael Blevins , Colin Green , Nick Blitterswyk
发明人： Dan Lucy , Michael Blevins , Colin Green , Nick Blitterswyk
CPC分类号： F03D3/0454 , F03D3/02 , F03D3/0409 , F03D3/0445 , F03D9/25 , F03D13/20 , F03D80/00 , F05B2240/13 , F05B2240/133 , F05B2240/40 , F05B2250/23 , Y02E10/74
摘要： Wind energy systems comprise a wind accelerator having a support assembly and an outer structure surrounding the support assembly. The wind accelerator has a front region and a rear region. The rear region is substantially wider than the front region, and the outer structure tapers from the rear region to the front region. One or more turbines are mounted on the support assembly at or near the rear region of the wind accelerator or at or near the widest point of the wind accelerator.
摘要翻译： 风能系统包括具有支撑组件和围绕支撑组件的外部结构的风力加速器。 风速加速器具有前部区域和后部区域。 后部区域比前部区域大得多，并且外部结构从后部区域向前部区域逐渐变细。 一个或多个涡轮机安装在风力加速器的后部区域处或附近的支撑组件上，或者在风力加速器的最宽点处或附近。
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公开(公告)号：US20070066555A1
公开(公告)日：2007-03-22
申请号：US11512728
申请日：2006-08-29
申请人： David Becker , Colin Green
发明人： David Becker , Colin Green
IPC分类号： A61K48/00
CPC分类号： C07H21/04 , A61K31/711 , A61K38/00 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2320/32
摘要： A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.
摘要翻译： 包含至少一种连接蛋白的反义多核苷酸与药学上可接受的载体或载体的治疗和/或化妆品制剂可用于连接蛋白表达的位点特异性下调，特别是在减少神经元细胞死亡，伤口愈合， 减少炎症，减少瘢痕形成和皮肤复原及增厚。
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8.发明申请METHOD AND APPARATUS FOR REMOTE CONTROLLING, MONITORING AND/OR SERVICING HEAT-TREATMENT EQUIPMENT VIA WIRELESS COMMUNICATIONS 有权通过无线通信远程控制，监控和/或维修热处理设备的方法和装置公开(公告)号：US20120025433A1
公开(公告)日：2012-02-02
申请号：US13252388
申请日：2011-10-04
IPC分类号： C21D11/00
CPC分类号： C21D11/00
摘要： A method and apparatus provide for remote control, monitoring and/or servicing of heat-treatment equipment via wireless communications networks. Specifically, the method and apparatus can be used in pre and post-weld heat-treatment applications for steel pipes in a variety of industries, including, but not limited to, power plants, chemical and petrochemical plants and refineries. Importantly, the embodiment generates and manages all the documentation necessary to input and verify the specified heat-treatment process. It will produce and deliver to the customer the reports and certificates required by the applicable quality control standards, requirements and regulatory authorities.
摘要翻译： 一种方法和设备提供经由无线通信网络的热处理设备的远程控制，监测和/或维修。 具体地说，该方法和装置可用于各种工业中的钢管的前后焊接热处理应用，包括但不限于发电厂，化工和石油化工厂和炼油厂。 重要的是，该实施例生成并管理输入和验证指定的热处理过程所需的所有文件。 它将生产和交付客户提供适用的质量控制标准，要求和监管机构所要求的报告和证书。
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公开(公告)号：US08034789B2
公开(公告)日：2011-10-11
申请号：US10581813
申请日：2004-12-03
申请人： Wilda Laux , Colin Green
发明人： Wilda Laux , Colin Green
CPC分类号： C12N15/113 , A61K31/7105 , A61K31/711 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2310/12 , C12N2310/315 , C12N2320/31 , Y02P20/582
摘要： Methods and compositions for modulating the activities of connexins are provided, including, for example, for use in post-surgical, trauma, or tissue engineering applications. These compounds and methods can be used therapeutically, for example, to reduce the severity of adverse effects associated diseases and disorders where localized disruption in direct cell-cell communication is desirable.
摘要翻译： 提供了用于调节连接蛋白活性的方法和组合物，包括例如用于手术后外伤，创伤或组织工程应用。 这些化合物和方法可以在治疗上使用，例如，降低相关疾病和病症的不良反应的严重性，其中期望直接细胞 - 细胞通讯的局部中断。
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公开(公告)号：US20110103942A1
公开(公告)日：2011-05-05
申请号：US12771898
申请日：2010-04-30
申请人： Colin Green , Nick Blitterswyk , Dan Lucy , Michael Blevins
发明人： Colin Green , Nick Blitterswyk , Dan Lucy , Michael Blevins
CPC分类号： F03D3/0454 , F03D3/02 , F03D3/0409 , F03D3/0445 , F03D9/25 , F03D13/20 , F03D80/00 , F05B2240/13 , F05B2240/133 , F05B2240/40 , F05B2250/23 , Y02E10/74
摘要： Wind energy systems comprise a wind accelerator having a support assembly and an outer structure surrounding the support assembly. The wind accelerator has a front region and a rear region. The rear region is substantially wider than the front region, and the outer structure tapers from the rear region to the front region. One or more turbines are mounted on the support assembly at or near the rear region of the wind accelerator or at or near the widest point of the wind accelerator.
摘要翻译： 风能系统包括具有支撑组件和围绕支撑组件的外部结构的风力加速器。 风速加速器具有前部区域和后部区域。 后部区域比前部区域大得多，并且外部结构从后部区域向前部区域逐渐变细。 一个或多个涡轮机安装在风力加速器的后部区域处或附近的支撑组件上，或者在风力加速器的最宽点处或附近。
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