Abstract:
A method for the preparation of a compound of formula (1) or a pharmaceutically acceptable salt or solvate thereof; from a compound of the formula: (IV); wherein L represents a leaving group.
Abstract:
There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
Abstract:
The present invention relates to a method of processing seismic data and other geophysical data such as acoustic or electromagnetic data. In particular the method is applicable to seismic data extrapolation and migration techniques such as, for example, one-way and two-way wave-equation migration. The method comprises determining, in the space-time domain, an integral of the product of a kernel and a function of the geophysical data over an integration domain from the values of the function at a plurality of discrete data points within the integration domain by defining a plurality of cells in the integration domain, each vertex of a cell being at a respective one of the data points; obtaining an interpolant of the function over a selected cell using local interpolation; and integrating, in the space-time domain, the product of the kernel and the interpolant for the selected cell.
Abstract:
Forward modeling is performed to compute a response of a target structure, the forward modeling accounting for distortion of a reflected signal from a reflector in the target structure. Waveform inversion is performed using the response of the forward modeling.
Abstract:
There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
Abstract:
There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
Abstract:
There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
Abstract:
There is provided a method of direct waveform inversion of turning waves (311, 312, 313) to determine parameters characterizing properties of the earth or sub-sections of the earth, particularly of parts of the earth which are capable of trapping hydrocarbons with the inversion yielding from the wavefield of turning waves information representing or being equivalent to velocities or slownesses and/or the gradient of velocities or slownesses, particularly by evaluating wavefield data in the vicinity of turning points (33). The method can be applied sequentially as a survey sinking method.
Abstract:
A method for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof; from a compound of the formula: (IV); wherein L represents a leaving group.