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1.NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN AMINE-FUNCTIONALIZED METHACRYLATE COPOLYMER 有权
标题翻译: 包含非离子聚合物和胺官能化甲基丙烯酸酯共聚物的纳米粒子公开(公告)号:US20100297237A1
公开(公告)日:2010-11-25
申请号:US12746752
申请日:2008-12-05
IPC分类号: A61K31/42 , A61K9/14 , A61K9/10 , A61K31/47 , A61K31/4196 , A61K31/5415
CPC分类号: A61K9/5138 , A61K9/0048 , A61K9/10 , A61K9/19 , A61K9/5161 , A61K9/5192
摘要: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an amine-functionalized methacrylate copolymer.
摘要翻译: 药物组合物包含包含难溶于水的药物,不良水溶性不可离子化聚合物和胺官能化甲基丙烯酸酯共聚物的纳米颗粒。
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2.Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer 有权
标题翻译: 包含不可离子化聚合物和胺官能化甲基丙烯酸酯共聚物的纳米颗粒公开(公告)号:US09233078B2
公开(公告)日:2016-01-12
申请号:US12746752
申请日:2008-12-05
IPC分类号: A61K31/47 , A61K31/4196 , A61K31/5415 , A61K9/51 , A61K9/00 , A61K9/10 , A61K9/19
CPC分类号: A61K9/5138 , A61K9/0048 , A61K9/10 , A61K9/19 , A61K9/5161 , A61K9/5192
摘要: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an amine-functionalized methacrylate copolymer.
摘要翻译: 药物组合物包含包含难溶于水的药物,不良水溶性不可离子化聚合物和胺官能化甲基丙烯酸酯共聚物的纳米颗粒。
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3.NANOPARTICLES COMPRISING A NON-IONIZABLE CELLULOSIC POLYMER AND AN AMPHIPHILIC NON-IONIZABLE BLOCK COPOLYMER 有权
标题翻译: 包含非离子型纤维素聚合物的纳米颗粒和非离子型非共轭嵌段共聚物公开(公告)号:US20100323014A1
公开(公告)日:2010-12-23
申请号:US12451810
申请日:2008-05-26
申请人: Corey Jay Bloom , Marshall David Crew , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
发明人: Corey Jay Bloom , Marshall David Crew , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
IPC分类号: A61K31/42 , A61K31/4706 , A61K31/415 , A61K9/14 , A61K9/10
CPC分类号: A61K9/5138 , A61K9/5161 , A61K9/5192 , A61K31/415 , A61K31/42 , A61K31/435 , A61K47/34 , A61K47/38 , Y10S977/773 , Y10S977/906
摘要: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
摘要翻译: 药物组合物包含包含难溶于水的药物,不良水溶性不可离子化纤维素聚合物和不良水溶性聚合物两亲性非可离子化嵌段共聚物的纳米颗粒。
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4.Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer 有权
标题翻译: 包含非离子化纤维素聚合物和两亲性非可离子化嵌段共聚物的纳米颗粒公开(公告)号:US08974827B2
公开(公告)日:2015-03-10
申请号:US12451810
申请日:2008-05-26
申请人: Corey Jay Bloom , Marshall David Crew , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
发明人: Corey Jay Bloom , Marshall David Crew , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
IPC分类号: A61K9/14 , A61K9/00 , A61K31/47 , A61K31/42 , A61K31/415 , A01N43/40 , A01N43/80 , A01N43/56 , A61K9/51 , A61K31/435 , A61K47/34 , A61K47/38
CPC分类号: A61K9/5138 , A61K9/5161 , A61K9/5192 , A61K31/415 , A61K31/42 , A61K31/435 , A61K47/34 , A61K47/38 , Y10S977/773 , Y10S977/906
摘要: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
摘要翻译: 药物组合物包含包含难溶于水的药物,不良水溶性不可离子化纤维素聚合物和不良水溶性聚合物两亲性非可离子化嵌段共聚物的纳米颗粒。
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5.Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer 失效
标题翻译: 包含胆固醇酯转移蛋白抑制剂和可离子化聚合物的纳米颗粒公开(公告)号:US08703204B2
公开(公告)日:2014-04-22
申请号:US12451288
申请日:2008-04-23
申请人: Corey Jay Bloom , Marshall David Crew , Daniel Tod Smithey , Warren Kenyon Miller , Michael Mark Morgen
发明人: Corey Jay Bloom , Marshall David Crew , Daniel Tod Smithey , Warren Kenyon Miller , Michael Mark Morgen
CPC分类号: A61K9/5146 , A61K9/5161 , A61K9/5192 , A61K31/4706
摘要: A pharmaceutical composition comprises nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a poorly aqueous soluble non-ionizable polymer.
摘要翻译: 药物组合物包含包含胆固醇酯转移蛋白抑制剂和不良水溶性不可离子化聚合物的纳米颗粒。
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6.NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN ANIONIC CELLULOSIC POLYMER 审中-公开
标题翻译: 包含非离子聚合物和阴离子型纤维素聚合物的纳米颗粒公开(公告)号:US20100266692A1
公开(公告)日:2010-10-21
申请号:US12451812
申请日:2008-06-30
IPC分类号: A61K9/14 , A61K31/42 , A61K31/47 , A61K31/415
CPC分类号: A61K9/5161 , A61K9/5192 , A61K31/00 , A61K31/415 , A61K31/42 , A61K31/635 , A61K47/38 , A61K2300/00
摘要: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an anionic cellulosic polymer.
摘要翻译: 药物组合物包含包含难溶于水的药物,不良水溶性非可离子化聚合物和阴离子纤维素聚合物的纳米颗粒。
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7.NANOPARTICLES COMPRISING IONIZABLE, POORLY WATER SOLUBLE CELLULOSIC POLYMERS 审中-公开
标题翻译: 包含可离子化,不溶于水的可溶性纤维素聚合物的纳米颗粒公开(公告)号:US20100215747A1
公开(公告)日:2010-08-26
申请号:US12451813
申请日:2008-06-30
申请人: Corey Jay Bloom , Marshall David Crew , Dwayne T. Friesen , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
发明人: Corey Jay Bloom , Marshall David Crew , Dwayne T. Friesen , Warren Kenyon Miller , Michael Mark Morgen , Daniel Tod Smithey
CPC分类号: A61K9/5161 , A61K9/5192 , A61K47/38
摘要: A pharmaceutical composition comprises nanoparticles comprising ionizable, poorly water soluble cellulosic polymers.
摘要翻译: 药物组合物包含包含可离子化的,难溶于水的纤维素聚合物的纳米颗粒。
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8.NANOPARTICLES COMPRISING A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR AND ANON-IONIZABLE POLYMER 失效
标题翻译: 包含乙醇转移蛋白抑制剂和非离子聚合物的纳米颗粒公开(公告)号:US20100129447A1
公开(公告)日:2010-05-27
申请号:US12451288
申请日:2008-04-23
申请人: Corey Jay Bloom , Marshall David Crew , Daniel Tod Smithey , Warren Kenyon Miller , Michael Mark Morgen
发明人: Corey Jay Bloom , Marshall David Crew , Daniel Tod Smithey , Warren Kenyon Miller , Michael Mark Morgen
CPC分类号: A61K9/5146 , A61K9/5161 , A61K9/5192 , A61K31/4706
摘要: A pharmaceutical composition comprises nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a poorly aqueous soluble non-ionizable polymer.
摘要翻译: 药物组合物包含包含胆固醇酯转移蛋白抑制剂和不良水溶性不可离子化聚合物的纳米颗粒。
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公开(公告)号:US06984403B2
公开(公告)日:2006-01-10
申请号:US10763340
申请日:2004-01-23
申请人: Timothy A. Hagen , Julian B. Lo , Avinash G. Thombre , Scott M. Herbig , Leah Elizabeth Appel , Marshall David Crew , Dwayne Thomas Friesen , David Keith Lyon , Scott Baldwin McCray , James Blair West
发明人: Timothy A. Hagen , Julian B. Lo , Avinash G. Thombre , Scott M. Herbig , Leah Elizabeth Appel , Marshall David Crew , Dwayne Thomas Friesen , David Keith Lyon , Scott Baldwin McCray , James Blair West
IPC分类号: A61K9/14
CPC分类号: A61K9/1611 , A61K9/143 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1641 , A61K9/1694 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K31/7052
摘要: The present invention is related to an oral dosage form comprising an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a glyceride which comprises glyceryl monobehenate, glyceryl dibehenate, glyceryl tribehenate, or a mixture thereof and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule.
摘要翻译: 本发明涉及包含有效量的碱化剂和阿奇霉素多颗粒的口服剂型,其中所述多颗粒包含阿奇霉素,其包含甘油单硬脂酸甘油酯,二苯乙酸甘油酯,枸橼酸甘油酯或其混合物和泊洛沙姆的甘油酯。 通常,口服剂型包括任何合适的口服给药方式,例如用于口服悬浮液的粉末,单位剂量包或小药囊,片剂或胶囊。
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公开(公告)号:US20080138428A1
公开(公告)日:2008-06-12
申请号:US11814501
申请日:2006-01-17
申请人: Roderick Jack Ray , Dwayne Thomas Friesen , Marshall David Crew , Richard Frank Falk , Sanjay Konagurthu
发明人: Roderick Jack Ray , Dwayne Thomas Friesen , Marshall David Crew , Richard Frank Falk , Sanjay Konagurthu
CPC分类号: A61K9/1617 , A61K9/0056 , A61K9/1652 , A61K9/2054
摘要: A highly porous, fast-disintegrating binder suitable for pharmaceutical applications and methods of making the same are disclosed, the binder comprising microporous particles of an aqueous-soluble cellulosic polymer and a wicking agent. Pharmaceutical compositions and fast-disintegrating dosage forms containing the binder are also disclosed.
摘要翻译: 公开了一种适用于药物应用的高度多孔,快速崩解的粘合剂及其制备方法,所述粘合剂包含水溶性纤维素聚合物的微孔颗粒和芯吸剂。 还公开了含有粘合剂的药物组合物和快速崩解剂型。
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