专利检索 ap:("Curtis Keith" OR "Alexis Borisy" OR "Grant R. Zimmermann" OR "Edward Roydon Jost-Price" OR "Palaniyandi Manivasakam" OR "Nicole Hurst" OR "Michael A. Foley" OR "Michael S. Slavonic" OR "Brendan Smith" OR "Benjamin A. Auspitz") AND inv:"Edward Roydon Jost-Price" 第 1 页

1.

发明申请
METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS 审中-公开
标题翻译：治疗免疫缺陷性疾病的方法和试剂

公开(公告)号：US20120058979A1

公开(公告)日：2012-03-08

申请号：US13292669

申请日：2011-11-09

申请人： Curtis Keith , Alexis Borisy , Grant R. Zimmermann , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley , Michael S. Slavonic , Brendan Smith , Benjamin A. Auspitz

发明人： Curtis Keith , Alexis Borisy , Grant R. Zimmermann , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley , Michael S. Slavonic , Brendan Smith , Benjamin A. Auspitz

IPC分类号： A61K31/573 , A61P37/06 , A61K31/575 , A61K31/568 , A61K31/58 , A61K31/57

CPC分类号： A61K31/565 , A61K9/0073 , A61K9/209 , A61K31/519 , A61K38/13 , A61K45/06 , A61K2300/00

摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.

摘要翻译： 本发明的特征在于一种通过向患者施用四取代的嘧啶并嘧啶，单独或与一种或多种另外的试剂组合来治疗诊断患有或有发展为免疫炎性疾病风险的患者的方法。本发明还特征在于含有四取代的嘧啶并嘧啶与一种或多种另外的试剂组合的组合物。

2.

发明授权
Methods and reagents for the treatment of immunoinflammatory disorders 失效
标题翻译：用于治疗免疫炎症疾病的方法和试剂

公开(公告)号：US08080553B2

公开(公告)日：2011-12-20

申请号：US11517593

申请日：2006-09-07

申请人： Curtis Keith , Alexis Borisy , Grant R. Zimmermann , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley , Michael S. Slavonic , Brendan Smith , Benjamin A. Auspitz

发明人： Curtis Keith , Alexis Borisy , Grant R. Zimmermann , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley , Michael S. Slavonic , Brendan Smith , Benjamin A. Auspitz

IPC分类号： A01N43/54 , A01N43/90 , A61K31/517 , A61K31/519 , C07D239/42 , C07D401/04

CPC分类号： A61K31/565 , A61K9/0073 , A61K9/209 , A61K31/519 , A61K38/13 , A61K45/06 , A61K2300/00

摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.

摘要翻译： 本发明的特征在于一种通过向患者施用四取代的嘧啶并嘧啶，单独或与一种或多种另外的试剂组合来治疗诊断患有或有风险发展免疫炎性疾病的患者的方法。本发明还特征在于含有四取代的嘧啶并嘧啶与一种或多种另外的试剂组合的组合物。

3.

发明申请
Methods and Reagents for the Treatment of Inflammatory Disorders 审中-公开
标题翻译：用于治疗炎性疾病的方法和试剂

公开(公告)号：US20090075951A1

公开(公告)日：2009-03-19

申请号：US12275134

申请日：2008-11-20

申请人： Benjamin A. Auspitz , Alexis Borisy , Jason Fong , Nicole Hurst , Edward Roydon Jost-Price , Curtis T. Keith , Palaniyandi Manivasakam , Robyn Sackeyfio , Michael S. Slavonic , Brendan Smith , Grant R. Zimmermann

发明人： Benjamin A. Auspitz , Alexis Borisy , Jason Fong , Nicole Hurst , Edward Roydon Jost-Price , Curtis T. Keith , Palaniyandi Manivasakam , Robyn Sackeyfio , Michael S. Slavonic , Brendan Smith , Grant R. Zimmermann

IPC分类号： A61K31/60 , A61K31/573

CPC分类号： A61K45/06 , A61K31/565 , A61K38/13 , A61K2300/00

摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.

摘要翻译： 本发明的特征在于一种通过向患者施用三环化合物和任选的皮质类固醇或其它化合物来治疗被诊断患有免疫炎症疾病或有风险的患者的方法。本发明还特征在于含有三环化合物和皮质类固醇或其它化合物的药物组合物，用于治疗或预防免疫炎性疾病。

4.

发明授权
Combinations for the treatment of immunoinflammatory disorders 失效
标题翻译：用于治疗免疫炎症障碍的组合

公开(公告)号：US07253155B2

公开(公告)日：2007-08-07

申请号：US10264991

申请日：2002-10-04

申请人： Curtis Keith , Alexis Borisy , Grant Zimmerman , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley

发明人： Curtis Keith , Alexis Borisy , Grant Zimmerman , Edward Roydon Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael A. Foley

IPC分类号： A61K31/56 , A61K31/517

CPC分类号： A61K45/06 , A61K31/519 , A61K31/56 , A61K31/573 , A61K31/675 , A61K2300/00

摘要： The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.

摘要翻译： 本发明的特征在于一种治疗具有免疫炎症病症的患者的方法，其通过给予患者（i）四取代的嘧啶并嘧啶，和（ii）皮质类固醇同时或彼此之间的14天内，其量足以减少或抑制免疫炎症。

5.

发明申请
METHODS AND REAGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS 审中-公开
标题翻译：用于治疗炎症性疾病的方法和试剂

公开(公告)号：US20100210606A1

公开(公告)日：2010-08-19

申请号：US12772693

申请日：2010-05-03

申请人： Edward Roydon Jost-Price , Palaniyandi Manivasakam , Brendan Smith , Michael S. Slavonic , Benjamin A. Auspitz

发明人： Edward Roydon Jost-Price , Palaniyandi Manivasakam , Brendan Smith , Michael S. Slavonic , Benjamin A. Auspitz

IPC分类号： A61K31/57 , A61K31/59 , A61K31/606 , A61P29/00 , A61P37/00 , A61P27/02 , A61P17/00

CPC分类号： A61K45/06 , A61K31/415 , A61K31/56 , A61K2300/00

摘要： The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.

摘要翻译： 本发明的特征在于一种方法，用于单独或与皮质类固醇，四取代嘧啶并嘧啶或其它化合物组合施用式（I）化合物，例如异丁司特或KC-764的免疫炎症的方法。本发明还包括药物组合物，包括上述用于治疗或预防免疫炎性疾病的组合。

6.

发明授权
Methods and reagents for the treatment of inflammatory disorders 失效
标题翻译：用于治疗炎性疾病的方法和试剂

公开(公告)号：US07709495B2

公开(公告)日：2010-05-04

申请号：US10992878

申请日：2004-11-19

申请人： Edward Roydon Jost-Price , Palaniyandi Manivasakam , Brendan Smith , Michael S. Slavonic , Benjamin A. Auspitz

发明人： Edward Roydon Jost-Price , Palaniyandi Manivasakam , Brendan Smith , Michael S. Slavonic , Benjamin A. Auspitz

IPC分类号： A01N43/42 , A61K31/44 , A61K31/56

CPC分类号： A61K45/06 , A61K31/415 , A61K31/56 , A61K2300/00

摘要： The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.

摘要翻译： 本发明的特征在于一种方法，用于单独或与皮质类固醇，四取代嘧啶并嘧啶或其它化合物组合施用式（I）化合物，例如异丁司特或KC-764的免疫炎症的方法。本发明还包括药物组合物，包括上述用于治疗或预防免疫炎性疾病的组合。

7.

发明授权
Combinations for the treatment of inflammatory disorders 失效
标题翻译：用于治疗炎症性疾病的组合

公开(公告)号：US06897206B2

公开(公告)日：2005-05-24

申请号：US10191149

申请日：2002-07-09

申请人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy

发明人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy

IPC分类号： A61K31/56 , A01N45/00 , A61K9/00 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/554 , A61K31/573 , A61K45/06 , A61P1/04 , A61P1/10 , A61P11/06 , A61P17/00 , A61P17/06 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/00 , A61P43/00 , G01N33/68

CPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/573 , A61K45/06 , G01N33/6863 , G01N2500/10 , Y10S514/825 , Y10S514/826 , Y10S514/863 , Y10S514/866 , Y10S514/958 , A61K2300/00

摘要： The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.

摘要翻译： 本发明的特征在于通过给予患者（i）三环类抗抑郁药（例如阿莫沙平）治疗患有炎性病症的患者的方法; 和（ii）皮质类固醇（例如强的松龙），其量以足以减少或抑制炎症的量彼此同时或者在14天内。