公开(公告)号：US20240423907A1

公开(公告)日：2024-12-26

申请号：US18760127

申请日：2024-07-01

Applicant: Cyrano Therapeutics, Inc.

Inventor： Richard GEOFFRION ,  Ronald KUPPERSMITH

IPC: A61K9/00 ,  A61P11/02

Abstract: Disclosed herein are methods of treating an allergic rhinitis, a nasal polyp, and/or a sinusitis in a subject, comprising intranasally administering to the subject a corticosteroid, an ester thereof, or a salt thereof by a nasal spray device. Also disclosed herein are devices and kits for administering corticosteroids, esters thereof, or salts thereof to a subject in need thereof. The nasal spray devices herein deliver a dosage unit that can be used to treat the diseases disclosed herein.

公开(公告)号：US20240423908A1

公开(公告)日：2024-12-26

申请号：US18760128

申请日：2024-07-01

Applicant: Cyrano Therapeutics, Inc.

Inventor： Richard GEOFFRION ,  Ronald KUPPERSMITH

IPC: A61K9/00 ,  A61K31/198 ,  A61K31/4015 ,  A61K31/445 ,  A61K31/522 ,  A61K45/06 ,  A61K47/10 ,  A61K47/20 ,  A61K47/38 ,  A61P25/16 ,  A61P25/28

Abstract: Disclosed herein are methods of treating Parkinson's disease in a subject, comprising intranasally administering to the subject phosphodiesterase inhibitors and treatments for Parkinson's disease by a nasal spray device. Also disclosed herein are devices and kits for administering the compositions described herein to a subject in need thereof. The nasal spray devices herein deliver a dosage unit that can be used to treat chemosensory dysfunction resulting from Parkinson's disease. Also described herein are treatments of other neurological diseases by a nasal spray device.

公开(公告)号：US20240423990A1

公开(公告)日：2024-12-26

申请号：US18760124

申请日：2024-07-01

Applicant: Cyrano Therapeutics, Inc.

Inventor： Richard GEOFFRION ,  Ronald KUPPERSMITH

IPC: A61K31/522 ,  A61K9/00 ,  A61K31/44 ,  A61K31/4515 ,  A61K31/4706 ,  A61K31/5415 ,  A61K31/5513 ,  A61P27/00

Abstract: Disclosed herein are methods of treating a chemosensory dysfunction in a subject, comprising intranasally administering to the subject a phosphodiesterase inhibitor or a salt thereof by a nasal spray device. Also disclosed herein are devices and kits for administering phosphodiesterase inhibitors or salts thereof to a subject in need thereof. The nasal spray devices herein deliver a dosage unit that can be used to treat chemosensory dysfunction from a viral infection or another underlying cause of chemosensory dysfunction.

公开(公告)号：US20240398816A1

公开(公告)日：2024-12-05

申请号：US18742344

申请日：2024-06-13

Applicant: Cyrano Therapeutics, Inc.

Inventor： Richard GEOFFRION ,  Ronald KUPPERSMITH

IPC: A61K31/522 ,  A61K9/00 ,  A61K9/06 ,  A61K47/32 ,  A61K47/38 ,  A61P27/00

Abstract: Disclosed herein are methods of treating chemosensory dysfunction in a subject, comprising administering to the subject a gel comprising a phosphodiesterase inhibitor. Also disclosed herein are methods of treating chemosensory dysfunction by administering a phosphodiesterase inhibitor to a subject in need thereof. Also disclosed herein are kits comprising gels.

公开(公告)号：US20250009649A1

公开(公告)日：2025-01-09

申请号：US18741915

申请日：2024-06-13

Applicant: Cyrano Therapeutics, Inc.

Inventor： Richard GEOFFRION ,  Ronald KUPPERSMITH

IPC: A61K9/00 ,  A61P27/00

Abstract: Disclosed herein are methods of treating chemosensory dysfunction in a subject, comprising administering to the subject a device such as a stent comprising a phosphodiesterase inhibitor. Also disclosed herein are devices comprising phosphodiesterase inhibitors, and kits comprising devices comprising phosphodiesterase inhibitors.