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1.
公开(公告)号:US20160200717A1
公开(公告)日:2016-07-14
申请号:US14823605
申请日:2015-08-11
申请人: Cytokinetics, Inc.
发明人: Luke W. Ashcroft , Gustave Bergnes , Scott Collibee , Chihyuan Chuang , Jeff Gardina , Bradley P. Morgan , Alex R Muci , Xiangping Qian , Antonio Romero , Jeffrey Warrington , Zhe Yang
IPC分类号: C07D417/14 , C07D213/75 , C07D401/14 , C07D253/07 , C07D403/04 , C07D213/74 , C07D401/12
CPC分类号: C07D213/74 , C07D213/75 , C07D213/78 , C07D213/82 , C07D215/38 , C07D215/48 , C07D253/07 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D417/04 , C07D417/14
摘要: Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R2, R4, R5, R6, R7, R8, R9, X, Z1, Z2, Z3, Z4 and m are as defined herein.Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof.Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.
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2.
公开(公告)号:US09994528B2
公开(公告)日:2018-06-12
申请号:US14823605
申请日:2015-08-11
申请人: Cytokinetics, Inc.
发明人: Luke W. Ashcraft , Gustave Bergnes , Scott Collibee , Chihyuan Chuang , Jeff Gardina , Bradley P. Morgan , Alex R Muci , Xiangping Qian , Antonio Romero , Jeffrey Warrington , Zhe Yang
IPC分类号: C07D213/74 , C07D213/75 , C07D401/12 , C07D401/14 , C07D417/14 , C07D417/04 , C07D403/04 , A61K31/44 , A61K31/4427 , A61P21/00 , A61P21/04 , C07D213/78 , C07D213/82 , C07D215/48 , C07D253/07 , C07D215/38 , C07D403/10
CPC分类号: C07D213/74 , C07D213/75 , C07D213/78 , C07D213/82 , C07D215/38 , C07D215/48 , C07D253/07 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D417/04 , C07D417/14
摘要: Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R2, R4, R5, R6, R7, R8, R9, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof.Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.
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