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公开(公告)号:US11415493B2
公开(公告)日:2022-08-16
申请号:US16085194
申请日:2017-03-17
IPC分类号: G01N1/30 , C12Q1/04 , A01B5/02 , C12M1/34 , B01L3/00 , C09B11/28 , C09B23/04 , C12Q1/68 , G01N21/64
摘要: The invention relates to a method for counting cells, such as bacteria and/or somatic cells in liquid samples, such as in dairy products, preferably raw milk. Disclosed is a method comprising a combination of steps that apply dimeric nucleic acid dyes that normally do not penetrate cells (=cell-impermeant dyes), which are rendered cell-permeant by using the right combination of pH, buffer and temperature.