公开(公告)号：US10328011B2

公开(公告)日：2019-06-25

申请号：US16060571

申请日：2016-12-09

Applicant: DSM IP ASSETS B.V.

Inventor： Remo Campiche ,  Dominik Imfeld ,  Alexandre Rio

IPC: A61K8/06 ,  A61K8/55 ,  A61K8/64 ,  A61Q19/00 ,  A61Q19/08

Abstract: Proline containing dipeptides are disclosed for up-regulating of genes involved in collagen fiber maturation and thus for revitalizing, strengthening and increasing the integrity of collagen fibers. These proline containing dipeptides are furthermore particularly suitable for improving the skin firmness, texture and elasticity as well as reducing the pore size and increasing skin moisturization.