公开(公告)号：US08952063B2

公开(公告)日：2015-02-10

申请号：US13890808

申请日：2013-05-09

Applicant: DSM IP Assets B.V.

Inventor： Arjen Sein ,  Damiet Josephina Petronella Cunera Koenders ,  Annika Viberg ,  Gerardus Johannes Franciscus Smolders ,  Anthonius Cornelis Van Den Vurg

IPC: A61K31/20 ,  A61K31/19 ,  A23C9/13 ,  A23L1/29 ,  A23L1/30 ,  A23L1/307 ,  A61K31/23

CPC classification number: A61K31/20 ,  A23C9/1315 ,  A23L33/115 ,  A23L33/12 ,  A23L33/20 ,  A23L33/30 ,  A61K31/23 ,  A61K2300/00

Abstract: The present invention relates to the field of weight management. The invention particularly relates to a method for inducing satiety. In one of its embodiments, the present invention provides a method for inducing satiety in a human or an animal comprising administering to said human or animal an effective amount of a composition comprising a lipid of which at least part is in a crystal form in the small intestine.

Abstract translation: 本发明涉及体重管理领域。 本发明特别涉及一种诱导饱腹感的方法。 在其一个实施方案中，本发明提供了一种在人或动物中诱导饱腹感的方法，包括向所述人或动物施用有效量的组合物，所述组合物包含至少部分为小颗粒中的晶体形式的脂质 肠。

公开(公告)号：US12290083B2

公开(公告)日：2025-05-06

申请号：US17620010

申请日：2020-06-18

Applicant: DSM IP ASSETS B.V.

Inventor： Ya-Hui Chien ,  Arjen Sein ,  Johanna Corline Margriet Vink

IPC: A23B7/157 ,  A23J3/14 ,  A23L2/38 ,  A23L2/66 ,  A23L25/00 ,  A23L29/262 ,  A23L29/269

Abstract: The present invention is directed to a composition comprising rapeseed protein, a hydrocolloid, and a vegetable oil, and to the use of such composition in food products such as a beverage.

公开(公告)号：US10457890B2

公开(公告)日：2019-10-29

申请号：US15564275

申请日：2016-04-08

Applicant: DSM IP ASSETS B.V.

Inventor： Arjen Sein ,  Rene Marcel De Jong ,  Evert Tjeerd Van Rij ,  Willem Bijleveld ,  Maarten Hotse Wilbrink

IPC: C11B3/00 ,  C12N9/16 ,  C12P7/64 ,  C12P7/20

Abstract: The present invention relates to a polypeptide having phospholipase C activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1. A process for degumming a vegetable oil comprising contacting a vegetable oil comprising phospholipids with a polypeptide having phospholipase C activity of the invention or a composition of the invention, wherein phospholipids are hydrolyzed into diacylglycerol and phosphate ester and/or phosphate, separating the phosphate ester and/or phosphate from the vegetable oil wherein a degummed vegetable oil is obtained.

公开(公告)号：US11999923B2

公开(公告)日：2024-06-04

申请号：US17052907

申请日：2019-05-06

Applicant: DSM IP ASSETS B.V.

Inventor： Ying Zha ,  Arjen Sein ,  Willem Bijleveld

IPC: C11B3/00

CPC classification number: C11B3/003 ,  C12Y301/01032

Abstract: The present invention relates to a process for reducing an amount of intact phospholipids in a triacylglyceride oil comprising incubating the oil with a polypeptide having phospholipase A1 activity, wherein the polypeptide comprises a polypeptide having at least 80% identity to the mature amino acid sequence of SEQ ID NO: 1.