公开(公告)号：US20190015429A1

公开(公告)日：2019-01-17

申请号：US15541793

申请日：2016-01-15

Applicant: DSM IP ASSETS B.V.

Inventor： Shuen Ei CHEN ,  Thau Kiong CHUNG ,  Daniel RAEDERSTORFF ,  Wolfgang SCHALCH

IPC: A61K31/593 ,  A23L33/155 ,  A23K20/174 ,  A23K50/75 ,  A23K20/179 ,  A61K31/375 ,  A61K31/355 ,  A61K31/015 ,  A61K31/047 ,  A61K31/01 ,  A61K31/122 ,  A61P15/08 ,  A61P3/04 ,  A61P9/00 ,  A61P3/06 ,  A61P3/10 ,  A61K31/525 ,  A61K31/675 ,  A61K31/455 ,  A61K31/197 ,  A61K31/519 ,  A61K31/4188 ,  A61K33/30 ,  A61K33/34 ,  A61K33/32 ,  A61K33/04

Abstract: This invention relates to the use of the combination of 25-hydroxyvitamin D3 (“25-OH D3”) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian 5 syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.

公开(公告)号：US20140194531A1

公开(公告)日：2014-07-10

申请号：US14148158

申请日：2014-01-06

Applicant: DSM IP Assets B.V.

Inventor： Jiankang LIU ,  Daniel RAEDERSTORFF ,  Ying WANG-SCHMIDT ,  Karin WERTZ

IPC: A61K31/05

CPC classification number: A61K31/05 ,  A61K36/63

Abstract: Hydroxytyrosol or olive juice containing hydroxytyrosol ca in can he used to maintain or increase mitochondria(biogenesis in cardiac muscle, skeletal muscles, and liver tissue.

Abstract translation: 含羟基酪醇的羟基酪醇或橄榄油可用于维持或增加线粒体（心肌，骨骼肌和肝组织中的生物发生）。

公开(公告)号：US20140162976A1

公开(公告)日：2014-06-12

申请号：US14182786

申请日：2014-02-18

Applicant: DSM IP ASSETS B.V.

Inventor： Daniel RAEDERSTORFF ,  Nathalie RICHARD ,  Joseph SCHWAGER ,  Karin WERTZ

IPC: A61K31/726 ,  A61K36/63 ,  A61K31/05

CPC classification number: A61K31/726 ,  A61K31/05 ,  A61K31/737 ,  A61K36/63 ,  A61K2300/00

Abstract: The present invention relates to novel compositions comprising hydroxytyrosol and chondroitin as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders.

Abstract translation: 本发明涉及包含羟基酪醇和软骨素的新型组合物以及这些组合物作为药物，特别是作为治疗，共同治疗或预防炎症性疾病的药物的用途。

公开(公告)号：US20200268773A1

公开(公告)日：2020-08-27

申请号：US15929310

申请日：2020-04-24

Applicant: DSM IP ASSETS B.V.

Inventor： Shuen Ei CHEN ,  Thau Kiong CHUNG ,  Daniel RAEDERSTORFF ,  Wolfgang SCHALCH

IPC: A61K31/593 ,  A23K20/174 ,  A23L33/155 ,  A61K31/047 ,  A61K31/122 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/519 ,  A61K33/04 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A23K50/75 ,  A23D7/005 ,  A23K20/158 ,  A61K31/592 ,  A23L33/15 ,  A23L33/105 ,  A61K31/05 ,  A23K20/20 ,  A23L33/16 ,  A61K31/065 ,  A61K31/045 ,  A61K45/06 ,  A23K20/179 ,  A61P9/00 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P15/08 ,  A61K31/01 ,  A61K31/015 ,  A61K31/197 ,  A61K31/525 ,  A61K31/675

Abstract: This invention relates to the use of the combination of 25-hydroxyvitamin D3 (“25-OH D3”) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.

公开(公告)号：US20160136108A1

公开(公告)日：2016-05-19

申请号：US15003777

申请日：2016-01-21

Applicant: DSM IP ASSETS B.V.

Inventor： Daniel RAEDERSTORFF ,  Joseph SCHWAGER ,  Karin WERTZ

IPC: A61K31/05

CPC classification number: A61K31/05 ,  A61K31/202 ,  A61K31/7004 ,  A61K31/737 ,  A61K2300/00

Abstract: The invention relates to the use of hydroxytyrosol for inducing or enhancing cartilage repair or cartilage regeneration. Furthermore, the invention relates to nutraceutical and pharmaceutical compositions comprising hydroxytyrosol for regeneration and repair of cartilage injuries in joints, in particular of traumatic cartilage injuries.