公开(公告)号：US20250032674A1

公开(公告)日：2025-01-30

申请号：US18718647

申请日：2022-12-12

Applicant: DSM IP ASSETS B.V.

Inventor： Mark Kenneth HAZZARD ,  Noel L. DAVISON ,  Mandy Maria Jozefina WIERMANS ,  Nicolaes Hubertus Maria DE BONT ,  Loes Heleen PLUYMEN

IPC: A61L27/48 ,  B32B5/02 ,  B32B27/12 ,  B32B27/40

Abstract: Disclosed herein are composite sheets and prosthetic medical devices formed therefrom. In an embodiment, a composite sheet has a thickness of 25-250 μm and comprises 10-70 mass %, based on the total mass of the composite sheet, of a knit fabric having thickness of 15-225 μm and comprising strands of 2-50 dtex, the strands comprising biocompatible polymer fibers, the strands comprising biocompatible polymer fibers, wherein the fabric comprises a thickness in a plurality of first locations, and pores in a plurality of second locations; and 30-90 mass %, based on the total mass of the composite sheet, of a polyurethane coating, wherein the polyurethane coating coats the fabric and fills the pores of the fabric such that the composite sheet is substantially impermeable to water.

公开(公告)号：US20230310718A1

公开(公告)日：2023-10-05

申请号：US18023801

申请日：2021-08-30

Applicant: DSM IP Assets B.V.

Inventor： Noel L. DAVISON ,  Mandy Maria Jozefina WIERMANS ,  Nicolaes Hubertus Maria DE BONT ,  Mark Kenneth HAZZARD

IPC: A61L31/06 ,  C08L75/04 ,  A61L31/14

CPC classification number: A61L31/06 ,  C08L75/04 ,  A61L31/14 ,  C08L2201/06 ,  C08L2203/02 ,  C08L2203/16 ,  A61L2400/18

Abstract: Disclosed herein is a polyurethane composite sheet comprising o a biocompatible and biostable polyurethane elastomer comprising polysiloxane segments, the polyurethane forming a continuous matrix of the sheet; and o a woven or braided fabric having a thickness of 15-150 μm and comprising biocompatible, high-strength polymer fibers; wherein the composite sheet comprises 10-90 mass % of polyurethane, has a thickness of 25-250 μm and an areal density of 5-300 g/m2; and wherein the composite sheet has, in at least one direction, non-linear uniaxial tensile behavior characterized by a 1%-secant modulus of 20-200 MPa, a hardening transition point at 10-45%, and a tensile strength of at least 25 MPa (measured in water at 37° C.).