公开(公告)号：US20160175457A1

公开(公告)日：2016-06-23

申请号：US14906600

申请日：2014-09-12

Applicant: DSM IP ASSETS B.V.

Inventor： Luppo EDENS ,  Peter Jan Leonard Mario QUAEDFLIEG ,  James P. PARAKKA ,  Petrus Johannes HERMSEN ,  Dennis HEEMSKERK ,  Michiel AKEROYD

IPC: A61K47/48 ,  A61K31/728 ,  A61K9/00

CPC classification number: A61K38/08 ,  A61K9/0051 ,  A61K31/728 ,  A61K47/65 ,  G02B1/043

Abstract: The present invention relates to a composition, such as a coating composition, comprising a peptide linked to a lubricant, wherein the peptide is cleavable by one or more proteinases present in tear fluid. The invention further relates to an ocular device comprising said composition, such as a preformed contact lens.

Abstract translation: 本发明涉及包含与润滑剂连接的肽的组合物，例如涂料组合物，其中所述肽可通过存在于泪液中的一种或多种蛋白酶切割。 本发明还涉及一种包括所述组合物的眼部装置，例如预成型的隐形眼镜。