-
公开(公告)号:US10041135B2
公开(公告)日:2018-08-07
申请号:US15119708
申请日:2015-02-20
Applicant: DSM IP ASSETS B.V.
Inventor: Roelof Hendrik Matthijs Kouwen , Pim Van Hee , Douwe Van Sinderen , Brian McDonnell , Jennifer Mahony
Abstract: Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR loci alterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
-
公开(公告)号:US11325986B2
公开(公告)日:2022-05-10
申请号:US15034231
申请日:2014-11-03
Applicant: DSM IP ASSETS B.V.
Inventor: Cornelia Elizabeth Paulina Maljaars , Pim Van Hee
IPC: C08B37/00 , A23C9/123 , C08L5/00 , C12P19/04 , A23C9/137 , A23C19/032 , A23C19/09 , C12N1/20 , A23C9/13 , A23C19/05 , C12R1/46
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
-
公开(公告)号:US11834525B2
公开(公告)日:2023-12-05
申请号:US17197476
申请日:2021-03-10
Applicant: DSM IP ASSETS B.V.
Inventor: Cornelia Elizabeth Paulina Maljaars , Pim Van Hee
IPC: C08B3/00 , A23C9/123 , C08L5/00 , C12P19/04 , A23C9/137 , A23C19/032 , A23C19/09 , C12N1/20 , A23C9/13 , A23C19/05 , C12R1/46 , C08B37/00
CPC classification number: C08B37/006 , A23C9/123 , A23C9/1238 , A23C9/1307 , A23C9/137 , A23C19/0323 , A23C19/054 , A23C19/09 , C08L5/00 , C12N1/20 , C12N1/205 , C12P19/04 , A23C2240/00 , A23Y2240/75 , C12R2001/46
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
-
公开(公告)号:US10519519B2
公开(公告)日:2019-12-31
申请号:US16025700
申请日:2018-07-02
Applicant: DSM IP ASSETS B.V.
Inventor: Roelof Hendrik Matthijs Kouwen , Pim Van Hee , Douwe Van Sinderen , Brian McDonnell , Jennifer Mahony
Abstract: Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR loci alterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
-
公开(公告)号:US20180305777A1
公开(公告)日:2018-10-25
申请号:US16025700
申请日:2018-07-02
Applicant: DSM IP ASSETS B.V.
Inventor: Roelof Hendrik Matthijs KOUWEN , Pim Van Hee , Douwe Van Sinderen , Brian McDonnell , Jennifer Mahony
Abstract: Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR loci alterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
-
-
-
-